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Protein
Submitted name:

LATS2C

Gene

Lats2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: MGI
  2. protein serine/threonine kinase activity Source: MGI

GO - Biological processi

  1. cellular protein localization Source: MGI
  2. G1/S transition of mitotic cell cycle Source: MGI
  3. hippo signaling Source: MGI
  4. hormone-mediated signaling pathway Source: MGI
  5. intracellular signal transduction Source: MGI
  6. keratinocyte differentiation Source: MGI
  7. mitotic nuclear division Source: InterPro
  8. negative regulation of canonical Wnt signaling pathway Source: MGI
  9. negative regulation of cyclin-dependent protein serine/threonine kinase activity Source: MGI
  10. protein phosphorylation Source: MGI
  11. regulation of organ growth Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
LATS2CImported
Submitted name:
Serine/threonine-protein kinase LATS2Imported
Gene namesi
Name:Lats2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1354386. Lats2.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. microtubule organizing center Source: MGI
  3. nucleus Source: MGI
  4. spindle pole Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ8VHE1.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118994.
HOGENOMiHOG000150627.
HOVERGENiHBG073574.

Family and domain databases

InterProiIPR028742. LATS2.
[Graphical view]
PANTHERiPTHR24356:SF149. PTHR24356:SF149. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8VHE1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KASTQGLLVG PNSDTSLDAK
60 70 80 90 100
VLGSKDASRQ QQMRATPKFG PYQKALREIR YSLLPFANES GTSAAAEVNR
110 120 130 140 150
QMLQELVNAG CDQVALNSQR YVCLSLSSAG VKGLCQKCVF IRKVSVADRL
160 170 180 190 200
CSRLWKILNR STMHIPGACL FLEMLLSVPP ISQTAAPGLQ AHRLLQLCSV
210 220
CEFKLGPSHL YLKHGASRLL SPLCP
Length:225
Mass (Da):24,657
Last modified:March 1, 2002 - v1
Checksum:i567CB8E0606690C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154504 Genomic DNA. No translation available.
AY015062 mRNA. Translation: AAK07726.1.
UniGeneiMm.347899.

Genome annotation databases

EnsembliENSMUST00000038381; ENSMUSP00000038982; ENSMUSG00000021959.
UCSCiuc007udn.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154504 Genomic DNA. No translation available.
AY015062 mRNA. Translation: AAK07726.1.
UniGeneiMm.347899.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000038381; ENSMUSP00000038982; ENSMUSG00000021959.
UCSCiuc007udn.1. mouse.

Organism-specific databases

MGIiMGI:1354386. Lats2.

Phylogenomic databases

GeneTreeiENSGT00760000118994.
HOGENOMiHOG000150627.
HOVERGENiHBG073574.

Miscellaneous databases

ChiTaRSiLats2. mouse.
SOURCEiSearch...

Gene expression databases

GenevestigatoriQ8VHE1.

Family and domain databases

InterProiIPR028742. LATS2.
[Graphical view]
PANTHERiPTHR24356:SF149. PTHR24356:SF149. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and Tissue Distribution of Two Novel Spliced Variants of the Mouse Lats2 Gene."
    Chen Y.-G., Mantalaris A., Wu J.H.D.
    Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
    Tissue: Bone marrowImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8VHE1_MOUSE
AccessioniPrimary (citable) accession number: Q8VHE1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: April 29, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.