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Protein

Solute carrier family 2, facilitated glucose transporter member 10

Gene

Slc2a10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Facilitative glucose transporter.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Enzyme and pathway databases

ReactomeiR-MMU-428790. Facilitative Na+-independent glucose transporters.

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 2, facilitated glucose transporter member 10
Alternative name(s):
Glucose transporter type 10
Short name:
GLUT-10
Gene namesi
Name:Slc2a10
Synonyms:Glut10
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:2156687. Slc2a10.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 15CytoplasmicSequence analysisAdd BLAST15
Transmembranei16 – 36Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini37 – 48ExtracellularSequence analysisAdd BLAST12
Transmembranei49 – 69Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini70 – 82CytoplasmicSequence analysisAdd BLAST13
Transmembranei83 – 103Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini104 – 107ExtracellularSequence analysis4
Transmembranei108 – 128Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini129 – 132CytoplasmicSequence analysis4
Transmembranei133 – 153Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini154 – 166ExtracellularSequence analysisAdd BLAST13
Transmembranei167 – 187Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini188 – 232CytoplasmicSequence analysisAdd BLAST45
Transmembranei233 – 253Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini254 – 269ExtracellularSequence analysisAdd BLAST16
Transmembranei270 – 290Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini291 – 298CytoplasmicSequence analysis8
Transmembranei299 – 319Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini320 – 402ExtracellularSequence analysisAdd BLAST83
Transmembranei403 – 423Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini424 – 442CytoplasmicSequence analysisAdd BLAST19
Transmembranei443 – 463Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini464 – 468ExtracellularSequence analysis5
Transmembranei469 – 489Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini490 – 536CytoplasmicSequence analysisAdd BLAST47

GO - Cellular componenti

  • cytoplasm Source: MGI
  • endomembrane system Source: UniProtKB-SubCell
  • integral component of plasma membrane Source: MGI
  • perinuclear region of cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002701921 – 536Solute carrier family 2, facilitated glucose transporter member 10Add BLAST536

Proteomic databases

PaxDbiQ8VHD6.
PRIDEiQ8VHD6.

PTM databases

PhosphoSitePlusiQ8VHD6.

Expressioni

Gene expression databases

BgeeiENSMUSG00000027661.
ExpressionAtlasiQ8VHD6. baseline and differential.
GenevisibleiQ8VHD6. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000029196.

Structurei

3D structure databases

ProteinModelPortaliQ8VHD6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0254. Eukaryota.
ENOG410XNQK. LUCA.
GeneTreeiENSGT00850000132274.
HOGENOMiHOG000202868.
HOVERGENiHBG051858.
InParanoidiQ8VHD6.
KOiK08147.
OMAiVTERPIH.
OrthoDBiEOG091G085H.
PhylomeDBiQ8VHD6.
TreeFamiTF332408.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 2 hits.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VHD6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLRPAVLLL CASVSLLGGL TFGYELAVIS GALLPLQLNF GLSCLEQELL
60 70 80 90 100
VGSLLLGALL ASLVGGFLID CYGRRRAILG SNAVLLAGSL ILGLASSLPW
110 120 130 140 150
LLLGRLSVGF AISLSSMACC IYVSELVGPR QRGVLVSLYE VGITVGILFS
160 170 180 190 200
YGLNYVLAGS PWGWRHMFGW AAAPALLQSL SLFLLPAGAE GTAAPKDLIP
210 220 230 240 250
LQGRETSKPG LVKPQYSFLD LFRAQDGMWS RTVVGLGLVL FQQLTGQPNV
260 270 280 290 300
LYYASTIFRS VGFHGGSSAV LASVGLGTVK VAATLVATGL VDRAGRRVLL
310 320 330 340 350
LFGCALMALS VSGIGLVSFA VSLDSGPSCL ATSNASQQVD LPGSSGLLVR
360 370 380 390 400
SSLPPVLHTN GDQGQLVLSV TERPIHPVIT ASLGPVLNTA SPVPTSPILE
410 420 430 440 450
HTLLCWSALV CMMVYVSAFS VGFGPVTWLV LSEIYPAEIR GRAFAFCSSF
460 470 480 490 500
NWAANLFISL SFLDLIGAIG LAWTFLLYGL TAVLGLAFIY LLVPETKGQS
510 520 530
LAEIEQQFQT SRFPLNFGHR QRIGIQYHRL DVSSAS
Length:536
Mass (Da):56,579
Last modified:March 1, 2002 - v1
Checksum:i789D14FE3C2477A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY029579 mRNA. Translation: AAK38739.1.
AK052156 mRNA. Translation: BAC34861.1.
CCDSiCCDS17083.1.
RefSeqiNP_569718.1. NM_130451.3.
UniGeneiMm.34147.

Genome annotation databases

EnsembliENSMUST00000029196; ENSMUSP00000029196; ENSMUSG00000027661.
GeneIDi170441.
KEGGimmu:170441.
UCSCiuc008nxv.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY029579 mRNA. Translation: AAK38739.1.
AK052156 mRNA. Translation: BAC34861.1.
CCDSiCCDS17083.1.
RefSeqiNP_569718.1. NM_130451.3.
UniGeneiMm.34147.

3D structure databases

ProteinModelPortaliQ8VHD6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000029196.

PTM databases

PhosphoSitePlusiQ8VHD6.

Proteomic databases

PaxDbiQ8VHD6.
PRIDEiQ8VHD6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000029196; ENSMUSP00000029196; ENSMUSG00000027661.
GeneIDi170441.
KEGGimmu:170441.
UCSCiuc008nxv.2. mouse.

Organism-specific databases

CTDi81031.
MGIiMGI:2156687. Slc2a10.

Phylogenomic databases

eggNOGiKOG0254. Eukaryota.
ENOG410XNQK. LUCA.
GeneTreeiENSGT00850000132274.
HOGENOMiHOG000202868.
HOVERGENiHBG051858.
InParanoidiQ8VHD6.
KOiK08147.
OMAiVTERPIH.
OrthoDBiEOG091G085H.
PhylomeDBiQ8VHD6.
TreeFamiTF332408.

Enzyme and pathway databases

ReactomeiR-MMU-428790. Facilitative Na+-independent glucose transporters.

Miscellaneous databases

PROiQ8VHD6.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000027661.
ExpressionAtlasiQ8VHD6. baseline and differential.
GenevisibleiQ8VHD6. MM.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 2 hits.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGTR10_MOUSE
AccessioniPrimary (citable) accession number: Q8VHD6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: March 1, 2002
Last modified: November 30, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.