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Protein

Cystatin

Gene

Cst6

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionProtease inhibitor, Thiol protease inhibitorUniRule annotation

Protein family/group databases

MEROPSiI25.006

Names & Taxonomyi

Protein namesi
Recommended name:
CystatinUniRule annotation
Gene namesi
Name:Cst6Imported
ORF Names:rCG_47933Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi628799 Cst6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28UniRule annotationAdd BLAST28
ChainiPRO_501398385529 – 149CystatinUniRule annotationAdd BLAST121

Expressioni

Gene expression databases

BgeeiENSRNOG00000020455

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027727

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 147CystatinInterPro annotationAdd BLAST115

Sequence similaritiesi

Belongs to the cystatin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J4P1 Eukaryota
ENOG410Y20I LUCA
GeneTreeiENSGT00900000140934
HOGENOMiHOG000231754
HOVERGENiHBG009556
KOiK13902
OMAiSLYYFRD
OrthoDBiEOG091G0TP1

Family and domain databases

CDDicd00042 CY, 1 hit
InterProiView protein in InterPro
IPR027214 Cystatin
IPR000010 Cystatin_dom
PANTHERiPTHR11413 PTHR11413, 1 hit
PfamiView protein in Pfam
PF00031 Cystatin, 1 hit
SMARTiView protein in SMART
SM00043 CY, 1 hit

Sequencei

Sequence statusi: Complete.

Q8VHC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERPHFPLAM GLGLLAFCLL TLSPDARAEL RSRRTGERQN LSPDDPRVLK
60 70 80 90 100
AAQAAVASYN MDSNSLYYFR DTKVIDAKCQ LVAGIKYYMT VDIESTECRK
110 120 130 140
TRVSGDHVDL TTCPLAAGVQ QEKLRCNFEL LEVPWKNTTQ LLKHDCVQV
Length:149
Mass (Da):16,792
Last modified:March 1, 2002 - v1
Checksum:i190DD8A89EC133C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07006112 Genomic DNA No translation available.
AY046415 mRNA Translation: AAL02328.1
CH473953 Genomic DNA Translation: EDM12473.1
RefSeqiNP_598250.1, NM_133566.1
UniGeneiRn.9609

Genome annotation databases

EnsembliENSRNOT00000027727; ENSRNOP00000027727; ENSRNOG00000020455
GeneIDi171096
KEGGirno:171096
UCSCiRGD:628799 rat

Similar proteinsi

Entry informationi

Entry nameiQ8VHC1_RAT
AccessioniPrimary (citable) accession number: Q8VHC1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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