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Protein

Cystatin

Gene

Cst6

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionProtease inhibitor, Thiol protease inhibitorUniRule annotation

Protein family/group databases

MEROPSiI25.006.

Names & Taxonomyi

Protein namesi
Recommended name:
CystatinUniRule annotation
Gene namesi
Name:Cst6Imported
ORF Names:rCG_47933Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi628799. Cst6.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28UniRule annotationAdd BLAST28
ChainiPRO_501112705129 – 149CystatinUniRule annotationAdd BLAST121

Expressioni

Gene expression databases

BgeeiENSRNOG00000020455.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027727.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 147CystatinInterPro annotationAdd BLAST115

Sequence similaritiesi

Belongs to the cystatin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J4P1. Eukaryota.
ENOG410Y20I. LUCA.
GeneTreeiENSGT00900000140934.
HOGENOMiHOG000231754.
HOVERGENiHBG009556.
KOiK13902.
OMAiSLYYFRD.
OrthoDBiEOG091G0TP1.

Family and domain databases

CDDicd00042. CY. 1 hit.
InterProiView protein in InterPro
IPR027214. Cystatin.
IPR000010. Cystatin_dom.
PANTHERiPTHR11413. PTHR11413. 1 hit.
PfamiView protein in Pfam
PF00031. Cystatin. 1 hit.
SMARTiView protein in SMART
SM00043. CY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8VHC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERPHFPLAM GLGLLAFCLL TLSPDARAEL RSRRTGERQN LSPDDPRVLK
60 70 80 90 100
AAQAAVASYN MDSNSLYYFR DTKVIDAKCQ LVAGIKYYMT VDIESTECRK
110 120 130 140
TRVSGDHVDL TTCPLAAGVQ QEKLRCNFEL LEVPWKNTTQ LLKHDCVQV
Length:149
Mass (Da):16,792
Last modified:March 1, 2002 - v1
Checksum:i190DD8A89EC133C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07006112 Genomic DNA. No translation available.
AY046415 mRNA. Translation: AAL02328.1.
CH473953 Genomic DNA. Translation: EDM12473.1.
RefSeqiNP_598250.1. NM_133566.1.
UniGeneiRn.9609.

Genome annotation databases

EnsembliENSRNOT00000027727; ENSRNOP00000027727; ENSRNOG00000020455.
GeneIDi171096.
KEGGirno:171096.
UCSCiRGD:628799. rat.

Similar proteinsi

Entry informationi

Entry nameiQ8VHC1_RAT
AccessioniPrimary (citable) accession number: Q8VHC1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: November 22, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported