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Q8VHC1

- Q8VHC1_RAT

UniProt

Q8VHC1 - Q8VHC1_RAT

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Protein
Submitted name:

Cystatin E/M

Gene
Cst6, rCG_47933
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. cysteine-type endopeptidase inhibitor activity Source: UniProtKB-KW

GO - Biological processi

  1. epidermis development Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Thiol protease inhibitorSAAS annotations

Protein family/group databases

MEROPSiI25.006.

Names & Taxonomyi

Protein namesi
Submitted name:
Cystatin E/MImported
Submitted name:
Cystatin NImported
Submitted name:
Cystatin-BImported
Gene namesi
Name:Cst6Imported
ORF Names:rCG_47933Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 1

Organism-specific databases

RGDi628799. Cst6.

Subcellular locationi

GO - Cellular componenti

  1. cornified envelope Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ8VHC1.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000027727.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG43465.
GeneTreeiENSGT00730000110979.
HOGENOMiHOG000231754.
HOVERGENiHBG009556.
InParanoidiQ8VHC1.
KOiK13902.
OMAiSLYYFRD.
OrthoDBiEOG7M98J9.

Family and domain databases

InterProiIPR027214. Cystatin.
IPR000010. Prot_inh_cystat.
IPR020381. Prot_inh_cystat_cons-reg.
[Graphical view]
PANTHERiPTHR11413. PTHR11413. 1 hit.
PfamiPF00031. Cystatin. 1 hit.
[Graphical view]
ProDomiPD001231. Prot_inh_cystat_cons-reg. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00043. CY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VHC1-1 [UniParc]FASTAAdd to Basket

« Hide

MERPHFPLAM GLGLLAFCLL TLSPDARAEL RSRRTGERQN LSPDDPRVLK    50
AAQAAVASYN MDSNSLYYFR DTKVIDAKCQ LVAGIKYYMT VDIESTECRK 100
TRVSGDHVDL TTCPLAAGVQ QEKLRCNFEL LEVPWKNTTQ LLKHDCVQV 149
Length:149
Mass (Da):16,792
Last modified:March 1, 2002 - v1
Checksum:i190DD8A89EC133C0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06009535 Genomic DNA. No translation available.
AY046415 mRNA. Translation: AAL02328.1.
CH473953 Genomic DNA. Translation: EDM12473.1.
RefSeqiNP_598250.1. NM_133566.1.
UniGeneiRn.9609.

Genome annotation databases

EnsembliENSRNOT00000027727; ENSRNOP00000027727; ENSRNOG00000020455.
GeneIDi171096.
KEGGirno:171096.
UCSCiRGD:628799. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06009535 Genomic DNA. No translation available.
AY046415 mRNA. Translation: AAL02328.1 .
CH473953 Genomic DNA. Translation: EDM12473.1 .
RefSeqi NP_598250.1. NM_133566.1.
UniGenei Rn.9609.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000027727.

Protein family/group databases

MEROPSi I25.006.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000027727 ; ENSRNOP00000027727 ; ENSRNOG00000020455 .
GeneIDi 171096.
KEGGi rno:171096.
UCSCi RGD:628799. rat.

Organism-specific databases

CTDi 1474.
RGDi 628799. Cst6.

Phylogenomic databases

eggNOGi NOG43465.
GeneTreei ENSGT00730000110979.
HOGENOMi HOG000231754.
HOVERGENi HBG009556.
InParanoidi Q8VHC1.
KOi K13902.
OMAi SLYYFRD.
OrthoDBi EOG7M98J9.

Miscellaneous databases

NextBioi 621762.
PROi Q8VHC1.

Gene expression databases

Genevestigatori Q8VHC1.

Family and domain databases

InterProi IPR027214. Cystatin.
IPR000010. Prot_inh_cystat.
IPR020381. Prot_inh_cystat_cons-reg.
[Graphical view ]
PANTHERi PTHR11413. PTHR11413. 1 hit.
Pfami PF00031. Cystatin. 1 hit.
[Graphical view ]
ProDomi PD001231. Prot_inh_cystat_cons-reg. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00043. CY. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization of a noval cysteine proteinase inhibitor, cystatin N."
    Hong J., Rosner M.R.
    Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiQ8VHC1_RAT
AccessioniPrimary (citable) accession number: Q8VHC1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: September 3, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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