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Q8VH00

- Q8VH00_MOUSE

UniProt

Q8VH00 - Q8VH00_MOUSE

Protein

Olfactory receptor

Gene

Olfr666

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. G-protein coupled receptor activity Source: UniProtKB-KW
    2. olfactory receptor activity Source: MGI

    GO - Biological processi

    1. detection of chemical stimulus involved in sensory perception of smell Source: GOC
    2. G-protein coupled receptor signaling pathway Source: MGI
    3. sensory perception of smell Source: MGI

    Keywords - Molecular functioni

    G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

    Keywords - Biological processi

    OlfactionSAAS annotation, Sensory transduction

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Olfactory receptorUniRule annotation
    Gene namesi
    Name:Olfr666Imported
    ORF Names:mCG_53563Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:3030500. Olfr666.

    Subcellular locationi

    Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

    GO - Cellular componenti

    1. integral component of membrane Source: MGI
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membraneSAAS annotation, Membrane

    Expressioni

    Gene expression databases

    GenevestigatoriQ8VH00.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000079893.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    eggNOGiNOG48028.
    GeneTreeiENSGT00740000115129.
    HOGENOMiHOG000041363.
    HOVERGENiHBG017625.
    InParanoidiQ8VH00.
    KOiK04257.
    OMAiGHNIPHH.
    OrthoDBiEOG7327P6.
    TreeFamiTF343679.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000725. Olfact_rcpt.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR00245. OLFACTORYR.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8VH00-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSGANSSSLT PEFFILNGVP GLEDAHVWIS LPFCFMYMIA VVGNCGLIYL    50
    IGHEEALHRP MYYFLALLSF TDVTLCTTTV PNMLCIFWFN FKKIGFNSCL 100
    VQMFFVHMLT GMESGVLMLM ALDRYVAICY PLRYTTILTN PVIAKAGLAT 150
    FLRSVMLIFP FTLLTKRLPY CRGSLIPHTY CDHMSVAKVS CGNAKVNAIY 200
    GLMVALLIGV FDICCISVSY TMILRAVVSL SSADARHKAF STCTSHICAI 250
    VITYVPAFFT FFTHRFGGHT IPHHVHIIVA NLYLLLPPTM NPIVYGVKTK 300
    QIRESVIKFL LGDKMGIT 318
    Length:318
    Mass (Da):35,466
    Last modified:March 1, 2002 - v1
    Checksum:iD5A89404A109C226
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC125170 Genomic DNA. No translation available.
    AY072990 Genomic DNA. Translation: AAL60653.1.
    AY317787 Genomic DNA. Translation: AAP71137.1.
    CH466531 Genomic DNA. Translation: EDL16743.1.
    RefSeqiNP_667307.1. NM_147096.1.
    UniGeneiMm.377842.

    Genome annotation databases

    EnsembliENSMUST00000081116; ENSMUSP00000079893; ENSMUSG00000063582.
    GeneIDi259100.
    KEGGimmu:259100.
    UCSCiuc009ixb.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC125170 Genomic DNA. No translation available.
    AY072990 Genomic DNA. Translation: AAL60653.1 .
    AY317787 Genomic DNA. Translation: AAP71137.1 .
    CH466531 Genomic DNA. Translation: EDL16743.1 .
    RefSeqi NP_667307.1. NM_147096.1.
    UniGenei Mm.377842.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000079893.

    Protein family/group databases

    GPCRDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000081116 ; ENSMUSP00000079893 ; ENSMUSG00000063582 .
    GeneIDi 259100.
    KEGGi mmu:259100.
    UCSCi uc009ixb.1. mouse.

    Organism-specific databases

    CTDi 259100.
    MGIi MGI:3030500. Olfr666.

    Phylogenomic databases

    eggNOGi NOG48028.
    GeneTreei ENSGT00740000115129.
    HOGENOMi HOG000041363.
    HOVERGENi HBG017625.
    InParanoidi Q8VH00.
    KOi K04257.
    OMAi GHNIPHH.
    OrthoDBi EOG7327P6.
    TreeFami TF343679.

    Miscellaneous databases

    NextBioi 391821.
    PROi Q8VH00.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8VH00.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000725. Olfact_rcpt.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR00245. OLFACTORYR.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Different evolutionary processes shaped the mouse and human olfactory receptor gene families."
      Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L., Trask B.J.
      Hum. Mol. Genet. 11:535-546(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "The olfactory receptor gene superfamily of the mouse."
      Zhang X., Firestein S.
      Nat. Neurosci. 5:124-133(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    3. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    4. Adams M.
      Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    5. "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels."
      Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., Trask B.J.
      Genome Biol. 4:R71.1-R71.13(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    6. Sanders K.
      Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    7. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    9. Ensembl
      Submitted (DEC-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ8VH00_MOUSE
    AccessioniPrimary (citable) accession number: Q8VH00
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3