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Q8VGZ7

- Q8VGZ7_MOUSE

UniProt

Q8VGZ7 - Q8VGZ7_MOUSE

Protein

Olfactory receptor

Gene

Olfr558

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 104 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. G-protein coupled receptor activity Source: UniProtKB-KW
    2. olfactory receptor activity Source: MGI

    GO - Biological processi

    1. detection of chemical stimulus involved in sensory perception of smell Source: GOC
    2. G-protein coupled receptor signaling pathway Source: MGI
    3. sensory perception of smell Source: MGI

    Keywords - Molecular functioni

    G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

    Keywords - Biological processi

    OlfactionSAAS annotation, Sensory transduction

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Olfactory receptorUniRule annotation
    Gene namesi
    Name:Olfr558Imported
    ORF Names:mCG_52015Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:3030392. Olfr558.

    Subcellular locationi

    Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

    GO - Cellular componenti

    1. integral component of membrane Source: MGI
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membraneSAAS annotation, Membrane

    Expressioni

    Gene expression databases

    GenevestigatoriQ8VGZ7.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117456.
    HOGENOMiHOG000041363.
    HOVERGENiHBG017625.
    InParanoidiQ8VGZ7.
    KOiK04257.
    OMAiSSMPKML.
    OrthoDBiEOG754HPV.
    TreeFamiTF342735.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000725. Olfact_rcpt.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR00245. OLFACTORYR.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8VGZ7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVGFNSNESS ATYFILIGLP GLEEVQFWLA FPLCSLYLIA VLGNLTIIYI    50
    VRTEHSLHEP MYIFLCMLSG LDILISTSSM PKMMAIFWFN STTIQFDACL 100
    VQMFAIHSLS GMESTVLLAM AFDRYVAICH PLRHATVLTL PRVAKIGMAA 150
    VVRGAVLMAP LPVFIKRLPF CRSNILSHSY CLHQDVMKLA CADIRVNIIY 200
    GLIVIISAIG LDSLLISFSY LLILKTVLGL TREAQAKAFG TCVSHVCAVF 250
    IFYVPFIGLS MVHRFSKRRD SLLPVIMANI YLLVPPVLNP IVYGVKTKEI 300
    RQRILRLFLV TTHTSDH 317
    Length:317
    Mass (Da):35,464
    Last modified:March 1, 2002 - v1
    Checksum:i5A0E59E229852534
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161431 Genomic DNA. No translation available.
    BC130658 mRNA. Translation: AAI30659.1.
    AY072993 Genomic DNA. Translation: AAL60656.1.
    AY317671 Genomic DNA. Translation: AAP71050.1.
    AY834217 mRNA. Translation: AAV97880.1.
    AK141545 mRNA. Translation: BAE24729.1.
    CH466531 Genomic DNA. Translation: EDL16621.1.
    CH466531 Genomic DNA. Translation: EDL16622.1.
    RefSeqiNP_667304.1. NM_147093.3.
    XP_006507940.1. XM_006507877.1.
    UniGeneiMm.121813.

    Genome annotation databases

    EnsembliENSMUST00000094124; ENSMUSP00000091674; ENSMUSG00000070423.
    GeneIDi259097.
    KEGGimmu:259097.
    UCSCiuc009isi.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161431 Genomic DNA. No translation available.
    BC130658 mRNA. Translation: AAI30659.1 .
    AY072993 Genomic DNA. Translation: AAL60656.1 .
    AY317671 Genomic DNA. Translation: AAP71050.1 .
    AY834217 mRNA. Translation: AAV97880.1 .
    AK141545 mRNA. Translation: BAE24729.1 .
    CH466531 Genomic DNA. Translation: EDL16621.1 .
    CH466531 Genomic DNA. Translation: EDL16622.1 .
    RefSeqi NP_667304.1. NM_147093.3.
    XP_006507940.1. XM_006507877.1.
    UniGenei Mm.121813.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    GPCRDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000094124 ; ENSMUSP00000091674 ; ENSMUSG00000070423 .
    GeneIDi 259097.
    KEGGi mmu:259097.
    UCSCi uc009isi.1. mouse.

    Organism-specific databases

    CTDi 259097.
    MGIi MGI:3030392. Olfr558.

    Phylogenomic databases

    GeneTreei ENSGT00750000117456.
    HOGENOMi HOG000041363.
    HOVERGENi HBG017625.
    InParanoidi Q8VGZ7.
    KOi K04257.
    OMAi SSMPKML.
    OrthoDBi EOG754HPV.
    TreeFami TF342735.

    Miscellaneous databases

    NextBioi 391809.
    PROi Q8VGZ7.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8VGZ7.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000725. Olfact_rcpt.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR00245. OLFACTORYR.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported.
    5. "Different evolutionary processes shaped the mouse and human olfactory receptor gene families."
      Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L., Trask B.J.
      Hum. Mol. Genet. 11:535-546(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    6. "The olfactory receptor gene superfamily of the mouse."
      Zhang X., Firestein S.
      Nat. Neurosci. 5:124-133(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    7. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported.
    8. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    9. Adams M.
      Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    10. "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels."
      Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., Trask B.J.
      Genome Biol. 4:R71.1-R71.13(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    11. Sanders K.
      Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    12. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: PCR rescued clonesImported.
    13. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported.
    14. "POGR, an olfactory G-protein coupled receptor, is overexpressed in human prostate and prostate cancers."
      Weng J., Wang J., Ittmann M., Liu M.
      Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    15. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported.
    16. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: HippocampusImported.
    17. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    18. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    19. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ8VGZ7_MOUSE
    AccessioniPrimary (citable) accession number: Q8VGZ7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 104 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3