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Protein

Olfactory receptor

Gene

Olfr558

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Keywords - Biological processi

OlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr558Imported
ORF Names:mCG_52015Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:3030392. Olfr558.

Subcellular locationi

  • Cell membrane UniRule annotationSAAS annotation; Multi-pass membrane protein UniRule annotationSAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei27 – 50HelicalUniRule annotationAdd BLAST24
Transmembranei62 – 80HelicalUniRule annotationAdd BLAST19
Transmembranei100 – 122HelicalUniRule annotationAdd BLAST23
Transmembranei143 – 165HelicalUniRule annotationAdd BLAST23
Transmembranei198 – 224HelicalUniRule annotationAdd BLAST27
Transmembranei236 – 256HelicalUniRule annotationAdd BLAST21
Transmembranei276 – 295HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000070423.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000091674.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 293G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST251

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IGD6. Eukaryota.
ENOG41120HT. LUCA.
GeneTreeiENSGT00840000129672.
HOGENOMiHOG000041363.
HOVERGENiHBG017625.
KOiK04257.
OMAiSSMPKML.
OrthoDBiEOG091G0AZH.
TreeFamiTF342735.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VGZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGFNSNESS ATYFILIGLP GLEEVQFWLA FPLCSLYLIA VLGNLTIIYI
60 70 80 90 100
VRTEHSLHEP MYIFLCMLSG LDILISTSSM PKMMAIFWFN STTIQFDACL
110 120 130 140 150
VQMFAIHSLS GMESTVLLAM AFDRYVAICH PLRHATVLTL PRVAKIGMAA
160 170 180 190 200
VVRGAVLMAP LPVFIKRLPF CRSNILSHSY CLHQDVMKLA CADIRVNIIY
210 220 230 240 250
GLIVIISAIG LDSLLISFSY LLILKTVLGL TREAQAKAFG TCVSHVCAVF
260 270 280 290 300
IFYVPFIGLS MVHRFSKRRD SLLPVIMANI YLLVPPVLNP IVYGVKTKEI
310
RQRILRLFLV TTHTSDH
Length:317
Mass (Da):35,464
Last modified:March 1, 2002 - v1
Checksum:i5A0E59E229852534
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC161431 Genomic DNA. No translation available.
BC130658 mRNA. Translation: AAI30659.1.
AY072993 Genomic DNA. Translation: AAL60656.1.
AY317671 Genomic DNA. Translation: AAP71050.1.
AY834217 mRNA. Translation: AAV97880.1.
AK141545 mRNA. Translation: BAE24729.1.
CH466531 Genomic DNA. Translation: EDL16621.1.
CH466531 Genomic DNA. Translation: EDL16622.1.
RefSeqiNP_667304.1. NM_147093.3.
XP_006507940.1. XM_006507877.2.
UniGeneiMm.121813.

Genome annotation databases

EnsembliENSMUST00000094124; ENSMUSP00000091674; ENSMUSG00000070423.
GeneIDi259097.
KEGGimmu:259097.
UCSCiuc009isi.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC161431 Genomic DNA. No translation available.
BC130658 mRNA. Translation: AAI30659.1.
AY072993 Genomic DNA. Translation: AAL60656.1.
AY317671 Genomic DNA. Translation: AAP71050.1.
AY834217 mRNA. Translation: AAV97880.1.
AK141545 mRNA. Translation: BAE24729.1.
CH466531 Genomic DNA. Translation: EDL16621.1.
CH466531 Genomic DNA. Translation: EDL16622.1.
RefSeqiNP_667304.1. NM_147093.3.
XP_006507940.1. XM_006507877.2.
UniGeneiMm.121813.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000091674.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000094124; ENSMUSP00000091674; ENSMUSG00000070423.
GeneIDi259097.
KEGGimmu:259097.
UCSCiuc009isi.1. mouse.

Organism-specific databases

CTDi259097.
MGIiMGI:3030392. Olfr558.

Phylogenomic databases

eggNOGiENOG410IGD6. Eukaryota.
ENOG41120HT. LUCA.
GeneTreeiENSGT00840000129672.
HOGENOMiHOG000041363.
HOVERGENiHBG017625.
KOiK04257.
OMAiSSMPKML.
OrthoDBiEOG091G0AZH.
TreeFamiTF342735.

Enzyme and pathway databases

ReactomeiR-MMU-381753. Olfactory Signaling Pathway.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000070423.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8VGZ7_MOUSE
AccessioniPrimary (citable) accession number: Q8VGZ7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: September 7, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.