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Q8VGZ7

- Q8VGZ7_MOUSE

UniProt

Q8VGZ7 - Q8VGZ7_MOUSE

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Protein

Olfactory receptor

Gene

Olfr558

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. olfactory receptor activity Source: MGI

GO - Biological processi

  1. detection of chemical stimulus involved in sensory perception of smell Source: GOC
  2. G-protein coupled receptor signaling pathway Source: MGI
  3. sensory perception of smell Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Keywords - Biological processi

OlfactionSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiREACT_252270. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr558Imported
ORF Names:mCG_52015Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:3030392. Olfr558.

Subcellular locationi

Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

GO - Cellular componenti

  1. integral component of membrane Source: MGI
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

GenevestigatoriQ8VGZ7.

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00770000120456.
HOGENOMiHOG000041363.
HOVERGENiHBG017625.
KOiK04257.
OMAiSSMPKML.
OrthoDBiEOG754HPV.
TreeFamiTF342735.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VGZ7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVGFNSNESS ATYFILIGLP GLEEVQFWLA FPLCSLYLIA VLGNLTIIYI
60 70 80 90 100
VRTEHSLHEP MYIFLCMLSG LDILISTSSM PKMMAIFWFN STTIQFDACL
110 120 130 140 150
VQMFAIHSLS GMESTVLLAM AFDRYVAICH PLRHATVLTL PRVAKIGMAA
160 170 180 190 200
VVRGAVLMAP LPVFIKRLPF CRSNILSHSY CLHQDVMKLA CADIRVNIIY
210 220 230 240 250
GLIVIISAIG LDSLLISFSY LLILKTVLGL TREAQAKAFG TCVSHVCAVF
260 270 280 290 300
IFYVPFIGLS MVHRFSKRRD SLLPVIMANI YLLVPPVLNP IVYGVKTKEI
310
RQRILRLFLV TTHTSDH
Length:317
Mass (Da):35,464
Last modified:March 1, 2002 - v1
Checksum:i5A0E59E229852534
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC161431 Genomic DNA. No translation available.
BC130658 mRNA. Translation: AAI30659.1.
AY072993 Genomic DNA. Translation: AAL60656.1.
AY317671 Genomic DNA. Translation: AAP71050.1.
AY834217 mRNA. Translation: AAV97880.1.
AK141545 mRNA. Translation: BAE24729.1.
CH466531 Genomic DNA. Translation: EDL16621.1.
CH466531 Genomic DNA. Translation: EDL16622.1.
RefSeqiNP_667304.1. NM_147093.3.
XP_006507940.1. XM_006507877.1.
UniGeneiMm.121813.

Genome annotation databases

EnsembliENSMUST00000094124; ENSMUSP00000091674; ENSMUSG00000070423.
GeneIDi259097.
KEGGimmu:259097.
UCSCiuc009isi.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC161431 Genomic DNA. No translation available.
BC130658 mRNA. Translation: AAI30659.1 .
AY072993 Genomic DNA. Translation: AAL60656.1 .
AY317671 Genomic DNA. Translation: AAP71050.1 .
AY834217 mRNA. Translation: AAV97880.1 .
AK141545 mRNA. Translation: BAE24729.1 .
CH466531 Genomic DNA. Translation: EDL16621.1 .
CH466531 Genomic DNA. Translation: EDL16622.1 .
RefSeqi NP_667304.1. NM_147093.3.
XP_006507940.1. XM_006507877.1.
UniGenei Mm.121813.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

GPCRDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000094124 ; ENSMUSP00000091674 ; ENSMUSG00000070423 .
GeneIDi 259097.
KEGGi mmu:259097.
UCSCi uc009isi.1. mouse.

Organism-specific databases

CTDi 259097.
MGIi MGI:3030392. Olfr558.

Phylogenomic databases

GeneTreei ENSGT00770000120456.
HOGENOMi HOG000041363.
HOVERGENi HBG017625.
KOi K04257.
OMAi SSMPKML.
OrthoDBi EOG754HPV.
TreeFami TF342735.

Enzyme and pathway databases

Reactomei REACT_252270. Olfactory Signaling Pathway.

Miscellaneous databases

NextBioi 391809.
PROi Q8VGZ7.
SOURCEi Search...

Gene expression databases

Genevestigatori Q8VGZ7.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view ]
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  5. "Different evolutionary processes shaped the mouse and human olfactory receptor gene families."
    Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L., Trask B.J.
    Hum. Mol. Genet. 11:535-546(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  6. "The olfactory receptor gene superfamily of the mouse."
    Zhang X., Firestein S.
    Nat. Neurosci. 5:124-133(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  7. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  8. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  9. Adams M.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  10. "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels."
    Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., Trask B.J.
    Genome Biol. 4:R71.1-R71.13(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  11. Sanders K.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  12. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.
  13. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  14. "POGR, an olfactory G-protein coupled receptor, is overexpressed in human prostate and prostate cancers."
    Weng J., Wang J., Ittmann M., Liu M.
    Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  15. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  16. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  17. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  18. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  19. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8VGZ7_MOUSE
AccessioniPrimary (citable) accession number: Q8VGZ7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: November 26, 2014
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3