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Q8VGV5

- Q8VGV5_MOUSE

UniProt

Q8VGV5 - Q8VGV5_MOUSE

Protein

Olfactory receptor

Gene

Olfr658

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 103 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. G-protein coupled receptor activity Source: UniProtKB-KW
    2. olfactory receptor activity Source: MGI

    GO - Biological processi

    1. detection of chemical stimulus involved in sensory perception of smell Source: GOC
    2. G-protein coupled receptor signaling pathway Source: MGI
    3. sensory perception of smell Source: MGI

    Keywords - Molecular functioni

    G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

    Keywords - Biological processi

    OlfactionSAAS annotation, Sensory transduction

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Olfactory receptorUniRule annotation
    Gene namesi
    Name:Olfr658Imported
    ORF Names:mCG_53102Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:3030492. Olfr658.

    Subcellular locationi

    Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

    GO - Cellular componenti

    1. integral component of membrane Source: MGI
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membraneSAAS annotation, Membrane

    Expressioni

    Gene expression databases

    GenevestigatoriQ8VGV5.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000115129.
    HOVERGENiHBG017625.
    InParanoidiQ8VGV5.
    KOiK04257.
    OMAiFSHRFGE.
    OrthoDBiEOG7327P6.
    TreeFamiTF343679.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000725. Olfact_rcpt.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR00245. OLFACTORYR.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8VGV5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVMSVQNSTD LTPASFVLNG IPGLEDMHIW ISFPFCSMYA VAMMGNCGLL    50
    YLIFFEDSLH RPMYYFLAML SLTDLVMCSS TIPKTLCIFW FHLKEIGFDD 100
    CLVQMFFIHT FTGMESGVLM LMALDRYVAI CYPLRYSTIL TNPIIAKIGL 150
    ATFLRGVLLI IPFTFLTKRL PYCRGNIINH TYCDHMSVAK LSCGNVKVNA 200
    IYGLMVALLI GGFDILCITI SYTMILRAVV SLSSADARQK AFSTCTAHIC 250
    AIVFSYSPAF FSFFSHRFGG HTIPPSCHII VANIYLLLPP TMNPVVYGVK 300
    TKQIRDCVIR ILSGSKDSKA HGI 323
    Length:323
    Mass (Da):36,060
    Last modified:March 1, 2002 - v1
    Checksum:i84FE6A4B4978C936
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC135109 Genomic DNA. No translation available.
    AY073039 Genomic DNA. Translation: AAL60702.1.
    AY317779 Genomic DNA. Translation: AAP71131.1.
    AK033992 mRNA. Translation: BAE20489.1.
    CH466531 Genomic DNA. Translation: EDL16736.1.
    RefSeqiNP_667260.1. NM_147049.4.
    UniGeneiMm.223432.

    Genome annotation databases

    EnsembliENSMUST00000089296; ENSMUSP00000086711; ENSMUSG00000070421.
    GeneIDi259051.
    KEGGimmu:259051.
    UCSCiuc009iwt.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC135109 Genomic DNA. No translation available.
    AY073039 Genomic DNA. Translation: AAL60702.1 .
    AY317779 Genomic DNA. Translation: AAP71131.1 .
    AK033992 mRNA. Translation: BAE20489.1 .
    CH466531 Genomic DNA. Translation: EDL16736.1 .
    RefSeqi NP_667260.1. NM_147049.4.
    UniGenei Mm.223432.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    GPCRDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000089296 ; ENSMUSP00000086711 ; ENSMUSG00000070421 .
    GeneIDi 259051.
    KEGGi mmu:259051.
    UCSCi uc009iwt.1. mouse.

    Organism-specific databases

    CTDi 259051.
    MGIi MGI:3030492. Olfr658.

    Phylogenomic databases

    GeneTreei ENSGT00740000115129.
    HOVERGENi HBG017625.
    InParanoidi Q8VGV5.
    KOi K04257.
    OMAi FSHRFGE.
    OrthoDBi EOG7327P6.
    TreeFami TF343679.

    Miscellaneous databases

    NextBioi 391653.
    PROi Q8VGV5.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q8VGV5.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000725. Olfact_rcpt.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR00245. OLFACTORYR.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    5. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    6. "Different evolutionary processes shaped the mouse and human olfactory receptor gene families."
      Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L., Trask B.J.
      Hum. Mol. Genet. 11:535-546(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    7. "The olfactory receptor gene superfamily of the mouse."
      Zhang X., Firestein S.
      Nat. Neurosci. 5:124-133(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    8. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    9. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    10. Adams M.
      Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    11. "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels."
      Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., Trask B.J.
      Genome Biol. 4:R71.1-R71.13(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    12. Sanders K.
      Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    13. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    14. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    15. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    16. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    17. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ8VGV5_MOUSE
    AccessioniPrimary (citable) accession number: Q8VGV5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 103 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3