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Protein
Submitted name:

MCG1050463

Gene

Olfr1512

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. olfactory receptor activity Source: MGI

GO - Biological processi

  1. detection of chemical stimulus involved in sensory perception of smell Source: GOC
  2. G-protein coupled receptor signaling pathway Source: MGI
  3. sensory perception of smell Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Keywords - Biological processi

OlfactionSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiREACT_252270. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
MCG1050463Imported
Submitted name:
Olfactory receptor 1512Imported
Submitted name:
Olfactory receptor MOR223-5Imported
Submitted name:
Olfactory receptor Olfr1512Imported
Submitted name:
Protein Olfr1512Imported
Gene namesi
Name:Olfr1512Imported
ORF Names:mCG_1050463Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 14

Organism-specific databases

MGIiMGI:3031346. Olfr1512.

Subcellular locationi

Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

GO - Cellular componenti

  1. integral component of membrane Source: MGI
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

GenevestigatoriQ8VF72.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000071208.

Structurei

3D structure databases

ProteinModelPortaliQ8VF72.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000119161.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
KOiK04257.
OMAiITVWADP.
OrthoDBiEOG7Z95MR.
TreeFamiTF337251.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VF72-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MERINYTVLT EFILTGVPHP PRLRTFLFVF FLLIYILTQL GNALILITVC
60 70 80 90 100
ADTQLHARPM YIFLGALSVI DMGISTIIVP RLMMNFTPGI KPIPFGGCVA
110 120 130 140 150
QLYFYHFLGS SQCFLYTTMA YDRYLAICQP LRYPVLMSAK LSILLVAGAW
160 170 180 190 200
VAGSIHGAIQ AILTFRLPYC GPNQVDYFFC DIPAVLKLAC ADTTVNELVT
210 220 230 240 250
FVDIGVVVAS CFSLILLSYI YIIRAILRIR TADGRRRAFS TCGAHVTIVT
260 270 280 290 300
VYYVPCAFIY LRPDSHSILD GAAALFPTAI TPFLNPLIYT LRNQEVKLAL
310
RRMVGSQSTK SEV
Length:313
Mass (Da):34,895
Last modified:March 1, 2002 - v1
Checksum:iCE4CE95BD2B35B8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126025 Genomic DNA. No translation available.
BC133656 mRNA. Translation: AAI33657.1.
AY073666 Genomic DNA. Translation: AAL61329.1.
AY318731 Genomic DNA. Translation: AAP71860.1.
CH466659 Genomic DNA. Translation: EDL42239.1.
RefSeqiNP_666643.1. NM_146432.2.
UniGeneiMm.377493.

Genome annotation databases

EnsembliENSMUST00000071221; ENSMUSP00000071208; ENSMUSG00000094140.
GeneIDi258424.
KEGGimmu:258424.
UCSCiuc007tph.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126025 Genomic DNA. No translation available.
BC133656 mRNA. Translation: AAI33657.1.
AY073666 Genomic DNA. Translation: AAL61329.1.
AY318731 Genomic DNA. Translation: AAP71860.1.
CH466659 Genomic DNA. Translation: EDL42239.1.
RefSeqiNP_666643.1. NM_146432.2.
UniGeneiMm.377493.

3D structure databases

ProteinModelPortaliQ8VF72.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000071208.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000071221; ENSMUSP00000071208; ENSMUSG00000094140.
GeneIDi258424.
KEGGimmu:258424.
UCSCiuc007tph.1. mouse.

Organism-specific databases

CTDi258424.
MGIiMGI:3031346. Olfr1512.

Phylogenomic databases

GeneTreeiENSGT00760000119161.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
KOiK04257.
OMAiITVWADP.
OrthoDBiEOG7Z95MR.
TreeFamiTF337251.

Enzyme and pathway databases

ReactomeiREACT_252270. Olfactory Signaling Pathway.

Miscellaneous databases

NextBioi389359.
PROiQ8VF72.
SOURCEiSearch...

Gene expression databases

GenevestigatoriQ8VF72.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Different evolutionary processes shaped the mouse and human olfactory receptor gene families."
    Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L., Trask B.J.
    Hum. Mol. Genet. 11:535-546(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The olfactory receptor gene superfamily of the mouse."
    Zhang X., Firestein S.
    Nat. Neurosci. 5:124-133(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  4. Adams M.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  5. "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels."
    Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., Trask B.J.
    Genome Biol. 4:R71.1-R71.13(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  6. Sanders K.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.
  8. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Ensembl
    Submitted (NOV-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8VF72_MOUSE
AccessioniPrimary (citable) accession number: Q8VF72
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: February 4, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.