Q8VF31 (Q8VF31_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Olfactory receptor 460 EMBL AAI19049.1

Submitted name:
Olfactory receptor MOR120-2 EMBL AAL61372.1
Submitted name:
Olfactory receptor Olfr460 EMBL AAP70968.1
Submitted name:
Protein Olfr460 Ensembl ENSMUSP00000054887

Gene names

Name:	Olfr460 Ensembl ENSMUSP00000054887 EMBL AAI19049.1 MGI 3030294
ORF Names:	mCG_52845 EMBL EDL13573.1

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	314 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein By similarity SAAS SAAS000725.
Sequence similarities	Belongs to the G-protein coupled receptor 1 family. RuleBase RU000688

Ontologies

Keywords
Biological process	Olfaction SAAS SAAS000725 Sensory transduction
Cellular component	Cell membrane SAAS SAAS000725 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS000725
Molecular function	G-protein coupled receptor SAAS SAAS000725 RuleBase RU000688 Receptor Transducer
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	G-protein coupled receptor signaling pathway Inferred from sequence alignment Ref.5. Source: MGI
Cellular_component	integral to membrane Inferred from sequence alignment Ref.5. Source: MGI plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW olfactory receptor activity Inferred from sequence alignment Ref.5. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8VF31 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 6BADEA6906D2E65D	FASTA	314	35,347
	10 20 30 40 50 60 MLGNHTSATE FYLVGFPGSV NLRHILFATF CFFYLVTLVG NTVIIVIVCV DKRLQSPMYF 70 80 90 100 110 120 FLVHLSILEI LVTTVIVPVM LWGLLLPGMQ SISLAGCVAQ LFLQLALGTT EFSLLGAMAV 130 140 150 160 170 180 DRYVAVCNPL RYSVIMNSRT CNSVVIVSWV FGFLFQIWPV YATFHLNYCK SNVVDNFFCD 190 200 210 220 230 240 RGQLLKLSCN NTIFIEFILF LMAVFVLFGS LIPTIVSYTY IIATILKIPS ASGRRKAFST 250 260 270 280 290 300 CASHFTCVVI GYGCCLFLYV KPKQTQAADY NRVVSLMISI VTPFLNPFIF TLRNDKVIEA 310 LRDGVKRCYH FFKS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Different evolutionary processes shaped the mouse and human olfactory receptor gene families." Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L., Trask B.J. Hum. Mol. Genet. 11:535-546(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The olfactory receptor gene superfamily of the mouse." Zhang X., Firestein S. Nat. Neurosci. 5:124-133(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D. Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL13573.1.
[4]	Adams M. Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[5]	"Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels." Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., Trask B.J. Genome Biol. 4:R71.1-R71.13(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[6]	Sanders K. Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[7]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain EMBL AAI19049.1.
[8]	Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL13573.1.
[9]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000054887.
[10]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000054887.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC153378 Genomic DNA. No translation available. BC119048 mRNA. Translation: AAI19049.1. BC120738 mRNA. Translation: AAI20739.1. AY073709 Genomic DNA. Translation: AAL61372.1. AY317568 Genomic DNA. Translation: AAP70968.1. CH466533 Genomic DNA. Translation: EDL13573.1.
IPI	IPI00125039.
RefSeq	NP_666495.1. NM_146383.1.
UniGene	Mm.377469.
3D structure databases
SMR	Q8VF31. Positions 35-306.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000054887.
Protein family/group databases
GPCRDB	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000051540; ENSMUSP00000054887; ENSMUSG00000045514.
GeneID	258381.
KEGG	mmu:258381.
UCSC	uc009bmz.1. mouse.
Organism-specific databases
CTD	258381.
MGI	MGI:3030294. Olfr460.
Phylogenomic databases
eggNOG	NOG119442.
GeneTree	ENSGT00550000074458.
HOGENOM	HOG000041364.
HOVERGEN	HBG017625.
InParanoid	Q8VF31.
KO	K04257.
OMA	MNYSSAT.
OrthoDB	EOG44J2JF.
Gene expression databases
Genevestigator	Q8VF31.
Family and domain databases
InterPro	IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR000725. Olfact_rcpt. [Graphical view]
PRINTS	PR00237. GPCRRHODOPSN. PR00245. OLFACTORYR.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	389189.
SOURCE	Search...

Entry information

Entry name

Q8VF31_MOUSE

Accession

Primary (citable) accession number: Q8VF31

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 88 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)