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Protein

Olfactory receptor

Gene

Olfr460

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Keywords - Biological processi

OlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr460Imported
ORF Names:mCG_52845Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:3030294. Olfr460.

Subcellular locationi

  • Cell membrane UniRule annotationSAAS annotation; Multi-pass membrane protein UniRule annotationSAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 50HelicalUniRule annotationAdd BLAST26
Transmembranei62 – 86HelicalUniRule annotationAdd BLAST25
Transmembranei92 – 120HelicalUniRule annotationAdd BLAST29
Transmembranei141 – 161HelicalUniRule annotationAdd BLAST21
Transmembranei193 – 226HelicalUniRule annotationAdd BLAST34
Transmembranei238 – 260HelicalUniRule annotationAdd BLAST23
Transmembranei272 – 292HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000054887.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 290G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST251

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410JB8S. Eukaryota.
ENOG41114F3. LUCA.
GeneTreeiENSGT00760000119169.
HOGENOMiHOG000041364.
HOVERGENiHBG017625.
KOiK04257.
OMAiMNSRTCN.
OrthoDBiEOG091G0FC8.
TreeFamiTF336833.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VF31-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGNHTSATE FYLVGFPGSV NLRHILFATF CFFYLVTLVG NTVIIVIVCV
60 70 80 90 100
DKRLQSPMYF FLVHLSILEI LVTTVIVPVM LWGLLLPGMQ SISLAGCVAQ
110 120 130 140 150
LFLQLALGTT EFSLLGAMAV DRYVAVCNPL RYSVIMNSRT CNSVVIVSWV
160 170 180 190 200
FGFLFQIWPV YATFHLNYCK SNVVDNFFCD RGQLLKLSCN NTIFIEFILF
210 220 230 240 250
LMAVFVLFGS LIPTIVSYTY IIATILKIPS ASGRRKAFST CASHFTCVVI
260 270 280 290 300
GYGCCLFLYV KPKQTQAADY NRVVSLMISI VTPFLNPFIF TLRNDKVIEA
310
LRDGVKRCYH FFKS
Length:314
Mass (Da):35,347
Last modified:March 1, 2002 - v1
Checksum:i6BADEA6906D2E65D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC153378 Genomic DNA. No translation available.
BC119048 mRNA. Translation: AAI19049.1.
BC120738 mRNA. Translation: AAI20739.1.
AY073709 Genomic DNA. Translation: AAL61372.1.
AY317568 Genomic DNA. Translation: AAP70968.1.
CH466533 Genomic DNA. Translation: EDL13573.1.
RefSeqiNP_666495.1. NM_146383.1.
XP_006506205.1. XM_006506142.2.
UniGeneiMm.377469.

Genome annotation databases

EnsembliENSMUST00000051540; ENSMUSP00000054887; ENSMUSG00000045514.
GeneIDi258381.
KEGGimmu:258381.
UCSCiuc009bmz.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC153378 Genomic DNA. No translation available.
BC119048 mRNA. Translation: AAI19049.1.
BC120738 mRNA. Translation: AAI20739.1.
AY073709 Genomic DNA. Translation: AAL61372.1.
AY317568 Genomic DNA. Translation: AAP70968.1.
CH466533 Genomic DNA. Translation: EDL13573.1.
RefSeqiNP_666495.1. NM_146383.1.
XP_006506205.1. XM_006506142.2.
UniGeneiMm.377469.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000054887.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000051540; ENSMUSP00000054887; ENSMUSG00000045514.
GeneIDi258381.
KEGGimmu:258381.
UCSCiuc009bmz.1. mouse.

Organism-specific databases

CTDi258381.
MGIiMGI:3030294. Olfr460.

Phylogenomic databases

eggNOGiENOG410JB8S. Eukaryota.
ENOG41114F3. LUCA.
GeneTreeiENSGT00760000119169.
HOGENOMiHOG000041364.
HOVERGENiHBG017625.
KOiK04257.
OMAiMNSRTCN.
OrthoDBiEOG091G0FC8.
TreeFamiTF336833.

Enzyme and pathway databases

ReactomeiR-MMU-381753. Olfactory Signaling Pathway.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8VF31_MOUSE
AccessioniPrimary (citable) accession number: Q8VF31
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: October 5, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.