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Q8VF31

- Q8VF31_MOUSE

UniProt

Q8VF31 - Q8VF31_MOUSE

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Protein

Olfactory receptor

Gene
Olfr460, mCG_52845
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. olfactory receptor activity Source: MGI

GO - Biological processi

  1. detection of chemical stimulus involved in sensory perception of smell Source: GOC
  2. G-protein coupled receptor signaling pathway Source: MGI
  3. sensory perception of smell Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotations, Receptor, Transducer

Keywords - Biological processi

OlfactionSAAS annotations, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr460Imported
ORF Names:mCG_52845Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 6

Organism-specific databases

MGIiMGI:3030294. Olfr460.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: MGI
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotations, Membrane

Expressioni

Gene expression databases

GenevestigatoriQ8VF31.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000054887.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

eggNOGiNOG119442.
GeneTreeiENSGT00730000110765.
HOGENOMiHOG000041364.
HOVERGENiHBG017625.
InParanoidiQ8VF31.
KOiK04257.
OMAiCNNTLFT.
OrthoDBiEOG7KM5TB.
TreeFamiTF336833.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VF31-1 [UniParc]FASTAAdd to Basket

« Hide

MLGNHTSATE FYLVGFPGSV NLRHILFATF CFFYLVTLVG NTVIIVIVCV    50
DKRLQSPMYF FLVHLSILEI LVTTVIVPVM LWGLLLPGMQ SISLAGCVAQ 100
LFLQLALGTT EFSLLGAMAV DRYVAVCNPL RYSVIMNSRT CNSVVIVSWV 150
FGFLFQIWPV YATFHLNYCK SNVVDNFFCD RGQLLKLSCN NTIFIEFILF 200
LMAVFVLFGS LIPTIVSYTY IIATILKIPS ASGRRKAFST CASHFTCVVI 250
GYGCCLFLYV KPKQTQAADY NRVVSLMISI VTPFLNPFIF TLRNDKVIEA 300
LRDGVKRCYH FFKS 314
Length:314
Mass (Da):35,347
Last modified:March 1, 2002 - v1
Checksum:i6BADEA6906D2E65D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC153378 Genomic DNA. No translation available.
BC119048 mRNA. Translation: AAI19049.1.
BC120738 mRNA. Translation: AAI20739.1.
AY073709 Genomic DNA. Translation: AAL61372.1.
AY317568 Genomic DNA. Translation: AAP70968.1.
CH466533 Genomic DNA. Translation: EDL13573.1.
RefSeqiNP_666495.1. NM_146383.1.
XP_006506205.1. XM_006506142.1.
UniGeneiMm.377469.

Genome annotation databases

EnsembliENSMUST00000051540; ENSMUSP00000054887; ENSMUSG00000045514.
GeneIDi258381.
KEGGimmu:258381.
UCSCiuc009bmz.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC153378 Genomic DNA. No translation available.
BC119048 mRNA. Translation: AAI19049.1 .
BC120738 mRNA. Translation: AAI20739.1 .
AY073709 Genomic DNA. Translation: AAL61372.1 .
AY317568 Genomic DNA. Translation: AAP70968.1 .
CH466533 Genomic DNA. Translation: EDL13573.1 .
RefSeqi NP_666495.1. NM_146383.1.
XP_006506205.1. XM_006506142.1.
UniGenei Mm.377469.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000054887.

Protein family/group databases

GPCRDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000051540 ; ENSMUSP00000054887 ; ENSMUSG00000045514 .
GeneIDi 258381.
KEGGi mmu:258381.
UCSCi uc009bmz.1. mouse.

Organism-specific databases

CTDi 258381.
MGIi MGI:3030294. Olfr460.

Phylogenomic databases

eggNOGi NOG119442.
GeneTreei ENSGT00730000110765.
HOGENOMi HOG000041364.
HOVERGENi HBG017625.
InParanoidi Q8VF31.
KOi K04257.
OMAi CNNTLFT.
OrthoDBi EOG7KM5TB.
TreeFami TF336833.

Miscellaneous databases

NextBioi 389189.
PROi Q8VF31.
SOURCEi Search...

Gene expression databases

Genevestigatori Q8VF31.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Different evolutionary processes shaped the mouse and human olfactory receptor gene families."
    Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L., Trask B.J.
    Hum. Mol. Genet. 11:535-546(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The olfactory receptor gene superfamily of the mouse."
    Zhang X., Firestein S.
    Nat. Neurosci. 5:124-133(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  4. Adams M.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  5. "Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels."
    Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A., Walker M., Williams E.M., Trask B.J.
    Genome Biol. 4:R71.1-R71.13(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  6. Sanders K.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  8. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8VF31_MOUSE
AccessioniPrimary (citable) accession number: Q8VF31
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: June 11, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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