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Protein

Olfactory receptor

Gene

Olfr448

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr448Imported
ORF Names:mCG_60445Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:3030282. Olfr448.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei23 – 50HelicalUniRule annotationAdd BLAST28
Transmembranei97 – 119HelicalUniRule annotationAdd BLAST23
Transmembranei139 – 163HelicalUniRule annotationAdd BLAST25
Transmembranei196 – 215HelicalUniRule annotationAdd BLAST20
Transmembranei236 – 260HelicalUniRule annotationAdd BLAST25
Transmembranei272 – 291HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000043119.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059195.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 289G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IHHV. Eukaryota.
ENOG410Z9E8. LUCA.
GeneTreeiENSGT00820000127003.
HOGENOMiHOG000041365.
HOVERGENiHBG017625.
KOiK04257.
OMAiRVLWKER.
OrthoDBiEOG091G0CU6.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
PfamiView protein in Pfam
PF13853. 7tm_4. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8VES9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTENQTWIPE FTLQGFLLSP RMQMLLCGLF SLLYTFTLLG NGVILGLIWL
60 70 80 90 100
DCRLHTPMYF FLSHLAIVDI SYATNNVPKM LANLLAKKKS ISFAPCIMQT
110 120 130 140 150
FLYMAFAHTE CLILVMMSYD RYAAICQPLQ YSVIMSWKVC TIMAVASWAC
160 170 180 190 200
GSLLALVHVV LILRLPFCGL HEINHFFCEI LSVLKLVCAD TTLNQIVIFA
210 220 230 240 250
GSVFILVGPL CFVLVSYTRI LIAILKIQSG EGRRKAFSTC SSHLCVVGLF
260 270 280 290 300
FGSAIVMYMA PKSQHPETQQ KVLSLFYSLF NPMLNPLIYS LRNAEVKGAV
310
KRVLWKQRSR
Length:310
Mass (Da):34,995
Last modified:March 1, 2002 - v1
Checksum:i356C2BE6FE667393
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC164628 Genomic DNA. No translation available.
BC107337 mRNA. Translation: AAI07338.1.
AY073820 Genomic DNA. Translation: AAL61483.1.
AY317555 Genomic DNA. Translation: AAP70958.1.
CH466533 Genomic DNA. Translation: EDL13461.1.
RefSeqiNP_666385.1. NM_146273.1.
UniGeneiMm.377404.

Genome annotation databases

EnsembliENSMUST00000058668; ENSMUSP00000059195; ENSMUSG00000043119.
ENSMUST00000213952; ENSMUSP00000150419; ENSMUSG00000043119.
ENSMUST00000214529; ENSMUSP00000148884; ENSMUSG00000043119.
GeneIDi258270.
KEGGimmu:258270.
UCSCiuc009bsa.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ8VES9_MOUSE
AccessioniPrimary (citable) accession number: Q8VES9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: November 22, 2017
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported