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Q8VE73

- CUL7_MOUSE

UniProt

Q8VE73 - CUL7_MOUSE

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Protein

Cullin-7

Gene
Cul7, Kiaa0076
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Core component of the 3M and Cul7-RING(FBXW8) complexes, which mediates the ubiquitination of target proteins. Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Interaction with CUL9 is required to inhibit CUL9 activity and ubiquitination of BIRC5. Core component of a Cul7-RING ubiquitin-protein ligase with FBXW8, which mediates ubiquitination and consequent degradation of target proteins such as GORASP1, IRS1 and MAP4K1/HPK1. Ubiquitination of GORASP1 regulates Golgi morphogenesis and dendrite patterning in brain. Mediates ubiquitination and degradation of IRS1 in a mTOR-dependent manner: the Cul7-RING(FBXW8) complex recognizes and binds IRS1 previously phosphorylated by S6 kinase (RPS6KB1 or RPS6KB2). The Cul7-RING(FBXW8) complex also mediates ubiquitination of MAP4K1/HPK1: recognizes and binds autophosphorylated MAP4K1/HPK1, leading to its degradatation, thereby affecting cell proliferation and differentiation. Acts as a regulator in trophoblast cell epithelial-mesenchymal transition and placental development. Does not promote polyubiquitination and proteasomal degradation of p53/TP53. While the Cul7-RING(FBXW8) and the 3M complexes are associated and involved in common processes, CUL7 and the Cul7-RING(FBXW8) complex may be have additional functions By similarity. Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation.

Pathwayi

GO - Molecular functioni

  1. protein binding Source: UniProtKB

GO - Biological processi

  1. Golgi organization Source: UniProtKB
  2. positive regulation of dendrite morphogenesis Source: UniProtKB
  3. protein ubiquitination Source: UniProtKB-UniPathway
  4. regulation of endothelial cell differentiation Source: UniProtKB
  5. ubiquitin-dependent protein catabolic process Source: InterPro
  6. vasculogenesis Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Ubl conjugation pathway

Enzyme and pathway databases

UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
Cullin-7
Short name:
CUL-7
Alternative name(s):
p185
p193
Gene namesi
Name:Cul7
Synonyms:Kiaa0076
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 17

Organism-specific databases

MGIiMGI:1913765. Cul7.

Subcellular locationi

Cytoplasm By similarity. Cytoplasmcytoskeletonmicrotubule organizing centercentrosome By similarity. Cytoplasmperinuclear region By similarity. Golgi apparatus By similarity
Note: Colocalizes with FBXW8 at the Golgi apparatus in neurons; localization to Golgi is mediated by OBSL1. During mitosis, localizes to the mitotic apparatus. CCDC8 is required for centrosomal location By similarity.

GO - Cellular componenti

  1. Cul7-RING ubiquitin ligase complex Source: UniProtKB
  2. Golgi apparatus Source: UniProtKB
  3. intracellular Source: UniProtKB
  4. nucleus Source: Ensembl
  5. perinuclear region of cytoplasm Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Golgi apparatus

Pathology & Biotechi

Disruption phenotypei

Mice are neonatal lethal and show vascular defects in both the embryo and the placenta.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 16891689Cullin-7PRO_0000119803Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Cross-linki1567 – 1567Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in NEDD8) Reviewed prediction

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

MaxQBiQ8VE73.
PaxDbiQ8VE73.
PRIDEiQ8VE73.

PTM databases

PhosphoSiteiQ8VE73.

Expressioni

Gene expression databases

ArrayExpressiQ8VE73.
BgeeiQ8VE73.
CleanExiMM_CUL7.
GenevestigatoriQ8VE73.

Interactioni

Subunit structurei

Component of the 3M complex, composed of core components CUL7, CCDC8 and OBSL1. Part of a Cul7-RING complex consisting of CUL7, RBX1, SKP1 and FBXW8. Interacts with a complex of SKP1 and FBXW8, but not with SKP1 alone. Interacts with CUL9; leading to inhibit CUL9 activity. Interacts with FBXW8; interaction is mutually exclusive of binding to CUL9 or p53/TP53. Interacts with p53/TP53; the interaction preferentially involves tetrameric and dimeric p53/TP53. The CUL7-CUL9 heterodimer seems to interact specifically with p53/TP53. Interacts with OBSL1 By similarity. Interacts with CUL1; the interactions seems to be mediated by FBXW8.

Protein-protein interaction databases

BioGridi211530. 6 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ8VE73.
SMRiQ8VE73. Positions 349-424.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini793 – 972180DOCAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni349 – 449101Interaction with TP53 By similarityAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi1308 – 137063Glu-richAdd
BLAST

Sequence similaritiesi

Belongs to the cullin family.
Contains 1 DOC domain.

Phylogenomic databases

eggNOGiNOG48148.
GeneTreeiENSGT00700000104406.
HOVERGENiHBG103792.
InParanoidiQ8VE73.
KOiK10613.
OMAiTFEHYYQ.
OrthoDBiEOG70S74H.
PhylomeDBiQ8VE73.
TreeFamiTF101154.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.25.10.10. 3 hits.
2.30.30.30. 1 hit.
2.60.120.260. 1 hit.
InterProiIPR004939. APC_su10/DOC_dom.
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR021097. CPH_domain.
IPR016157. Cullin_CS.
IPR016158. Cullin_homology.
IPR001373. Cullin_N.
IPR008979. Galactose-bd-like.
IPR014722. Rib_L2_dom2.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF03256. APC10. 1 hit.
PF11515. Cul7. 1 hit.
PF00888. Cullin. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF75632. SSF75632. 2 hits.
PROSITEiPS01256. CULLIN_1. 1 hit.
PS50069. CULLIN_2. 1 hit.
PS51284. DOC. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q8VE73-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MVGELRYREF RVPLGPGLHA YPDELIRQRV GHNGHPEYQI RWLILRRGDD     50
GDRDSTVDCK AEHILLWMSD DEIYANCHKM LGENGQVIAP SRESTEAGAL 100
DKSVLGEMET DVKSLIQRAL RQLEECVGTV PPAPLLHTVH VLSAYASIEP 150
LTGIFKDRRV VNLLMHMLSS PDYQIRWSAG RMIQALSSHD AGTRTQILLS 200
LSQQEAIEKH LDFDSRCALL ALFAQATLTE HPMSFEGVQL PQVPGRLLFS 250
LVKRYLHVTF LLDRLNGDAG DQGAQNNFIP EELNVGRGRL ELEFSMAMGT 300
LISELVQAMR WDGASSRPES SSSSTFQPRP AQFRPYTQRF RRSRRFRPRA 350
SFASFNTYAL YVRDTLRPGM RVRMLENYEE IAAGDEGQFR QSNDGVPPAQ 400
VLWDSTGHTY WVHWHMLEIL GFEEDIEDVI DIEELQELGA NGALSIVPPS 450
QRWKPITQLF AEPYVVPEEE DREESENLTQ AEWWELLFFI RQLSEAERLH 500
IVDLLQDHLE EERVLDYDML PELTVPVDLA QDLLLSLPQQ LEDSALRDLF 550
SCSVYRKYGP EVLVGHLSYP FVPGAQPNLF GANEESEAKD PPLQSASPAL 600
QRLVESLGPE GEVLVELEQA LGSEAPQETE VKSCLLQLQE QPQPFLALMR 650
SLDTSASNKT LHLTVLRILM QLVNFPEALL LPWHEAMDAC VTCLRSPNTD 700
REVLQELIFF LHRLTTTSRD YAVILNQLGA RDAISKVLEK HRGKLELAQE 750
LRDMVSKCEK HAHLYRKLTT NILGGCIQMV LGQIEDHRRT HRPIQIPFFD 800
VFLRYLCQGS SEEMKKNRYW EKVEVSSNPQ RASRLTDRNP KTYWESSGRA 850
GSHFITLHMR PGVIIRQLTL LVAGEDSSYM PAWVVVCGGN SIKSVNKELN 900
TVNVMPSASR VTLLENLTRF WPIIQIRIKR CQQGGINTRI RGLEVLGPKP 950
TFWPVFREQL CRHTRLFYMV RAQAWSQDIA EDRRSLLHLS SRLNGALRHE 1000
QNFAERFLPD MEAAQALSKT CWEALVSPLV QNITSPDEDS TSSLGWLLDQ 1050
YLGCREAAYN PQSRAAAFSS RVRRLTHLLV HVEPREAAPP VVAIPRSKGR 1100
NRIHDWSYLI TRGLPSSIMK NLTRCWRSVV EEQMNKFLTA SWKDDDFVPR 1150
YCERYYVLQK SSSELFGPRA AFLLAMRNGC ADAVLRLPFL RAAHVSEQFA 1200
RHIDQRIQGS RMGGARGMEM LAQLQRCLES VLIFSPLEIA TTFEHYYQHY 1250
MADRLLSVGS SWLEGAVLEQ IGPCFPSRLP QQMLQSLNVS EELQRQFHVY 1300
QLQQLDQELL KLEDTEKKIQ VAHEDSGRED KSKKEEAIGE AAAVAMAEEE 1350
DQGKKEEGEE EGEGEDEEEE RYYKGTMPEV CVLVVTPRFW PVASVCQMLN 1400
PATCLPAYLR GTINHYTNFY SKSQSRSSLE KEPQRRLQWT WQGRAEVQFG 1450
GQILHVSTVQ MWLLLHLNNQ KEVSVESLQA ISELPPDVLH RAIGPLTSSR 1500
GPLDLQEQKN VPGGVLKIRD DSEEPRPRRG NVWLIPPQTY LQAEAEEGRN 1550
MEKRRNLLNC LVVRILKAHG DEGLHVDRLV YLVLEAWEKG PCPARGLVSS 1600
LGRGATCRSS DVLSCILHLL VKGTLRRHDD RPQVLYYAVP VTVMEPHMES 1650
LNPGSAGPNP PLTFHTLQIR SRGVPYASCT DNHTFSTFR 1689
Length:1,689
Mass (Da):192,292
Last modified:January 9, 2007 - v2
Checksum:i6ED4641B577E53CD
GO
Isoform 2 (identifier: Q8VE73-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1472-1472: Missing.

Note: No experimental confirmation available.

Show »
Length:1,688
Mass (Da):192,163
Checksum:i8AD13BBC66EAA8A5
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1472 – 14721Missing in isoform 2. VSP_038331

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti395 – 3951G → V in BAE27723. 1 Publication
Sequence conflicti518 – 5181D → E in BAD32160. 1 Publication
Sequence conflicti777 – 7793IQM → DAW in AAH19645. 1 Publication
Sequence conflicti855 – 92268Missing in AAH59865. 1 PublicationAdd
BLAST
Sequence conflicti888 – 8881G → R in BAE27723. 1 Publication
Sequence conflicti959 – 9591Q → E in AAH59865. 1 Publication
Sequence conflicti1482 – 14821S → L in BAB25811. 1 Publication
Sequence conflicti1495 – 14951P → L in BAB25811. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK008655 mRNA. Translation: BAB25811.1.
AK147156 mRNA. Translation: BAE27723.1.
CT030702 Genomic DNA. No translation available.
BC019645 mRNA. Translation: AAH19645.1.
BC026946 mRNA. Translation: AAH26946.2.
BC059865 mRNA. Translation: AAH59865.1.
BC100544 mRNA. Translation: AAI00545.1.
AK172882 mRNA. Translation: BAD32160.1.
CCDSiCCDS28833.1. [Q8VE73-1]
RefSeqiNP_079887.3. NM_025611.5. [Q8VE73-1]
UniGeneiMm.329078.

Genome annotation databases

EnsembliENSMUST00000043464; ENSMUSP00000049128; ENSMUSG00000038545. [Q8VE73-1]
GeneIDi66515.
KEGGimmu:66515.
UCSCiuc008ctp.1. mouse. [Q8VE73-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK008655 mRNA. Translation: BAB25811.1 .
AK147156 mRNA. Translation: BAE27723.1 .
CT030702 Genomic DNA. No translation available.
BC019645 mRNA. Translation: AAH19645.1 .
BC026946 mRNA. Translation: AAH26946.2 .
BC059865 mRNA. Translation: AAH59865.1 .
BC100544 mRNA. Translation: AAI00545.1 .
AK172882 mRNA. Translation: BAD32160.1 .
CCDSi CCDS28833.1. [Q8VE73-1 ]
RefSeqi NP_079887.3. NM_025611.5. [Q8VE73-1 ]
UniGenei Mm.329078.

3D structure databases

ProteinModelPortali Q8VE73.
SMRi Q8VE73. Positions 349-424.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 211530. 6 interactions.

PTM databases

PhosphoSitei Q8VE73.

Proteomic databases

MaxQBi Q8VE73.
PaxDbi Q8VE73.
PRIDEi Q8VE73.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000043464 ; ENSMUSP00000049128 ; ENSMUSG00000038545 . [Q8VE73-1 ]
GeneIDi 66515.
KEGGi mmu:66515.
UCSCi uc008ctp.1. mouse. [Q8VE73-1 ]

Organism-specific databases

CTDi 9820.
MGIi MGI:1913765. Cul7.
Rougei Search...

Phylogenomic databases

eggNOGi NOG48148.
GeneTreei ENSGT00700000104406.
HOVERGENi HBG103792.
InParanoidi Q8VE73.
KOi K10613.
OMAi TFEHYYQ.
OrthoDBi EOG70S74H.
PhylomeDBi Q8VE73.
TreeFami TF101154.

Enzyme and pathway databases

UniPathwayi UPA00143 .

Miscellaneous databases

ChiTaRSi CUL7. mouse.
NextBioi 321916.
PROi Q8VE73.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q8VE73.
Bgeei Q8VE73.
CleanExi MM_CUL7.
Genevestigatori Q8VE73.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
1.25.10.10. 3 hits.
2.30.30.30. 1 hit.
2.60.120.260. 1 hit.
InterProi IPR004939. APC_su10/DOC_dom.
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR021097. CPH_domain.
IPR016157. Cullin_CS.
IPR016158. Cullin_homology.
IPR001373. Cullin_N.
IPR008979. Galactose-bd-like.
IPR014722. Rib_L2_dom2.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF03256. APC10. 1 hit.
PF11515. Cul7. 1 hit.
PF00888. Cullin. 1 hit.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF75632. SSF75632. 2 hits.
PROSITEi PS01256. CULLIN_1. 1 hit.
PS50069. CULLIN_2. 1 hit.
PS51284. DOC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Strain: C57BL/6J.
    Tissue: Stomach.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 299-1689 (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 777-1689 (ISOFORM 1).
    Strain: C57BL/6 and Czech II.
    Tissue: Brain, Jaw, Limb and Mammary gland.
  4. "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Seino S., Nishimura M., Kaisho T., Hoshino K., Kitamura H., Nagase T., Ohara O., Koga H.
    DNA Res. 11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 182-1689 (ISOFORM 1).
    Tissue: Fetal brain.
  5. "Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis."
    Arai T., Kasper J.S., Skaar J.R., Ali S.H., Takahashi C., DeCaprio J.A.
    Proc. Natl. Acad. Sci. U.S.A. 100:9855-9860(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISRUPTION PHENOTYPE.
  6. "Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development."
    Tsunematsu R., Nishiyama M., Kotoshiba S., Saiga T., Kamura T., Nakayama K.I.
    Mol. Cell. Biol. 26:6157-6169(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH CUL1 AND FBXW8.

Entry informationi

Entry nameiCUL7_MOUSE
AccessioniPrimary (citable) accession number: Q8VE73
Secondary accession number(s): Q3UHY3
, Q497I2, Q6A0D6, Q6PB63, Q8R3W4, Q9CVD5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: January 9, 2007
Last modified: September 3, 2014
This is version 109 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi