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Protein

Tetratricopeptide repeat protein 39C

Gene

Ttc39c

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Tetratricopeptide repeat protein 39C
Short name:
TPR repeat protein 39C
Gene namesi
Name:Ttc39c
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1919997. Ttc39c.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 580580Tetratricopeptide repeat protein 39CPRO_0000274353Add
BLAST

Proteomic databases

EPDiQ8VE09.
MaxQBiQ8VE09.
PaxDbiQ8VE09.
PRIDEiQ8VE09.

PTM databases

iPTMnetiQ8VE09.
PhosphoSiteiQ8VE09.

Interactioni

Protein-protein interaction databases

IntActiQ8VE09. 1 interaction.
MINTiMINT-4390945.
STRINGi10090.ENSMUSP00000025294.

Structurei

3D structure databases

ProteinModelPortaliQ8VE09.
SMRiQ8VE09. Positions 32-93.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati312 – 34534TPR 1Add
BLAST
Repeati350 – 38334TPR 2Add
BLAST
Repeati482 – 51534TPR 3Add
BLAST

Sequence similaritiesi

Belongs to the TTC39 family.Curated
Contains 3 TPR repeats.Curated

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiKOG3783. Eukaryota.
ENOG410XTBZ. LUCA.
HOGENOMiHOG000007788.
HOVERGENiHBG081333.
InParanoidiQ8VE09.
PhylomeDBiQ8VE09.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
InterProiIPR019412. OMP_Iml2/TPR_39.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF10300. DUF3808. 1 hit.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8VE09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGSEEQWPR RREDGDPDAA AAPLQDAELA LAGINMLLNN GFRESDQLFK
60 70 80 90 100
QYRNHSPLMS FGASFVSFLN AMMTFEEEKM QLACDDLKTT EKLCESEEAG
110 120 130 140 150
VIETIKNKIK KNVDARKSTP SMVDRLQRQI IIADCQVYLA VLSFVKQELS
160 170 180 190 200
AYIKGGWILR KAWKIYSKCY VDINALQELY QKKLTEEPLA SDAANDNHVV
210 220 230 240 250
AEGVTEESLS RLKGAVSFGY GLFHLCISMV PPNLLKIINL LGFPGDRLQG
260 270 280 290 300
LSSLTYASES KDMKAPLATL ALLWYHTVVR PFFALDGSDN KGGLDEAKAI
310 320 330 340 350
LLRKESAYPN SSLFMFFKGR IQRLECQINS ALTSFHTALE LAVDQREIQH
360 370 380 390 400
VCLYEIGWCS MIELNFKDAF DSFERLKNES RWSQCYYAYL TAVCQGATGD
410 420 430 440 450
VDGAQLVFKE VQKLFKRKNN QIEQFSVKKA ERFRKQTPTR ALCVLASIEV
460 470 480 490 500
LYLWKALPNC SFPNLQRMSQ ACHEVDDSSV VGLKHLLLGA IHKCLGNSQD
510 520 530 540 550
ALQFFQRAAR DELCRQSNSY VPPYACYELG CLLLDSAETV GRGRTLLLQA
560 570 580
KEDFSGYDFE NRLHVRIHAA LASLRELVPQ
Length:580
Mass (Da):65,445
Last modified:February 6, 2007 - v2
Checksum:i654A029231C284B2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti28 – 292EL → DV in BAB28758 (PubMed:16141072).Curated
Sequence conflicti408 – 4081F → L in BAB28758 (PubMed:16141072).Curated
Sequence conflicti526 – 5261C → S in AAH20021 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK013267 mRNA. Translation: BAB28758.1.
BC020021 mRNA. Translation: AAH20021.1.
CCDSiCCDS29065.1.
RefSeqiNP_082617.2. NM_028341.4.
UniGeneiMm.52526.

Genome annotation databases

GeneIDi72747.
KEGGimmu:72747.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK013267 mRNA. Translation: BAB28758.1.
BC020021 mRNA. Translation: AAH20021.1.
CCDSiCCDS29065.1.
RefSeqiNP_082617.2. NM_028341.4.
UniGeneiMm.52526.

3D structure databases

ProteinModelPortaliQ8VE09.
SMRiQ8VE09. Positions 32-93.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8VE09. 1 interaction.
MINTiMINT-4390945.
STRINGi10090.ENSMUSP00000025294.

PTM databases

iPTMnetiQ8VE09.
PhosphoSiteiQ8VE09.

Proteomic databases

EPDiQ8VE09.
MaxQBiQ8VE09.
PaxDbiQ8VE09.
PRIDEiQ8VE09.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi72747.
KEGGimmu:72747.

Organism-specific databases

CTDi125488.
MGIiMGI:1919997. Ttc39c.

Phylogenomic databases

eggNOGiKOG3783. Eukaryota.
ENOG410XTBZ. LUCA.
HOGENOMiHOG000007788.
HOVERGENiHBG081333.
InParanoidiQ8VE09.
PhylomeDBiQ8VE09.

Miscellaneous databases

PROiQ8VE09.
SOURCEiSearch...

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
InterProiIPR019412. OMP_Iml2/TPR_39.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF10300. DUF3808. 1 hit.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Embryo.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: 129.
    Tissue: Mammary tumor.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain, Liver and Testis.

Entry informationi

Entry nameiTT39C_MOUSE
AccessioniPrimary (citable) accession number: Q8VE09
Secondary accession number(s): Q9CYV6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 6, 2007
Last modified: June 8, 2016
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.