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Protein
Submitted name:

Homeobox protein OTX2

Gene

Otx2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi38 – 97HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Homeobox protein OTX2Imported
Submitted name:
Orthodenticle homolog 2 (Drosophila), isoform CRA_aImported
Submitted name:
Otx2 proteinImported
Gene namesi
Name:Otx2Imported
ORF Names:mCG_12117Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:97451. Otx2.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000021848.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 96Homeobox DNA-bindingInterPro annotationAdd BLAST61

Keywords - Domaini

HomeoboxPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2251. Eukaryota.
ENOG4111XIJ. LUCA.
GeneTreeiENSGT00820000126963.
HOVERGENiHBG004028.
KOiK18490.

Family and domain databases

InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR003022. Otx2_TF.
IPR003025. Otx_TF.
IPR013851. Otx_TF_C.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PF03529. TF_Otx. 1 hit.
PRINTSiPR01257. OTX2HOMEOBOX.
PR01255. OTXHOMEOBOX.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8VD35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSYLKQPPY AVNGLSLTTS GMDLLHPSVG YPATPRKQRR ERTTFTRAQL
60 70 80 90 100
DVLEALFAKT RYPDIFMREE VALKINLPES RVQVWFKNRR AKCRQQQQQQ
110 120 130 140 150
QNGGQNKVRP AKKKSSPARE VSSESGTSGQ FSPPSSTSVP TIASSSAPVS
160 170 180 190 200
IWSPASISPL SDPLSTSSSC MQRSYPMTYT QASGYSQGYA GSTSYFGGMD
210 220 230 240 250
CGSYLTPMHH QLPGPGATLS PMGTNAVTSH LNQSPASLST QGYGASSLGF
260 270 280
NSTTDCLDYK DQTASWKLNF NADCLDYKDQ TSSWKFQVL
Length:289
Mass (Da):31,608
Last modified:March 1, 2002 - v1
Checksum:iEEAF2A5FA9781CAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC166574 Genomic DNA. No translation available.
BC017609 mRNA. Translation: AAH17609.1.
AK053741 mRNA. Translation: BAC35500.1.
AK081535 mRNA. Translation: BAC38249.1.
AK087527 mRNA. Translation: BAC39913.1.
CH466605 Genomic DNA. Translation: EDL20772.1.
CH466605 Genomic DNA. Translation: EDL20774.1.
RefSeqiNP_001273410.1. NM_001286481.1.
NP_001273411.1. NM_001286482.1.
NP_001273412.1. NM_001286483.1.
NP_659090.1. NM_144841.4.
XP_011243291.1. XM_011244989.2.
XP_017171406.1. XM_017315917.1.
UniGeneiMm.134516.
Mm.487292.

Genome annotation databases

EnsembliENSMUST00000118578; ENSMUSP00000113690; ENSMUSG00000021848.
ENSMUST00000122009; ENSMUSP00000113930; ENSMUSG00000021848.
GeneIDi18424.
KEGGimmu:18424.
UCSCiuc007tjq.3. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ8VD35_MOUSE
AccessioniPrimary (citable) accession number: Q8VD35
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: August 30, 2017
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported