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Protein
Submitted name:

Glycosylphosphatidylinositol specific phospholipase D1

Gene

Gpld1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-163125. Post-translational modification: synthesis of GPI-anchored proteins.

Names & Taxonomyi

Protein namesi
Submitted name:
Glycosylphosphatidylinositol specific phospholipase D1Imported
Submitted name:
Glycosylphosphatidylinositol specific phospholipase D1, isoform CRA_bImported
Submitted name:
Phosphatidylinositol-glycan-specific phospholipase DImported
Gene namesi
Name:Gpld1Imported
ORF Names:mCG_3149Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:106604. Gpld1.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_501084735024 – 842Sequence analysisAdd BLAST819

Expressioni

Gene expression databases

BgeeiENSMUSG00000021340.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 211Zn_dep_PLPCInterPro annotationAdd BLAST184
Repeati367 – 428FG-GAPPROSITE-ProRule annotationAdd BLAST62
Repeati435 – 497FG-GAPPROSITE-ProRule annotationAdd BLAST63
Repeati499 – 559FG-GAPPROSITE-ProRule annotationAdd BLAST61
Repeati566 – 624FG-GAPPROSITE-ProRule annotationAdd BLAST59
Repeati634 – 694FG-GAPPROSITE-ProRule annotationAdd BLAST61
Repeati706 – 772FG-GAPPROSITE-ProRule annotationAdd BLAST67
Repeati790 – 842FG-GAPPROSITE-ProRule annotationAdd BLAST53

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IPB3. Eukaryota.
ENOG4111ZDA. LUCA.
GeneTreeiENSGT00390000013522.
HOVERGENiHBG008185.
KOiK01127.
OMAiAQYVLIS.
OrthoDBiEOG091G01DS.
TreeFamiTF335726.

Family and domain databases

InterProiView protein in InterPro
IPR013517. FG-GAP.
IPR001028. Gprt_PLipase_D.
IPR013519. Int_alpha_beta-p.
IPR029002. PLPC/GPLD1.
PfamiView protein in Pfam
PF01839. FG-GAP. 3 hits.
PF00882. Zn_dep_PLPC. 1 hit.
PRINTSiPR00718. PHPHLIPASED.
SMARTiView protein in SMART
SM00191. Int_alpha. 5 hits.
PROSITEiView protein in PROSITE
PS51470. FG_GAP. 7 hits.

Sequencei

Sequence statusi: Complete.

Q8VCU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAGRLWSSL LLLLPLFCSK SSSCGLSTHV EIGHRALEFL RLQDGRINYK
60 70 80 90 100
ELILEHQDAY QAGTVFPDAF YPSICKRGKY HDVSERTHWT PFLNASIHYI
110 120 130 140 150
RENYPLPWEK DTEKLVAFLF GITSHMVADV SWHSLGIEQG FLRTMGAIDF
160 170 180 190 200
YNSYSDAHSA GDFGGDVLSQ FEFNFNYLSR RWYVPVRDLL RIYDNLYGRK
210 220 230 240 250
VITKDVLVDC TYLQFLEMHG EMFAVSKLYS TYSTKSPFLV EQFQDYFLGG
260 270 280 290 300
LDDMAFWSTN IYRLTSFMLE NGTSDCNLPE NPLFISCDGR NHTLSGSKVQ
310 320 330 340 350
KNDFHRNLTM FISRDIRKNL NYTERGVFYS TGSWAPESVT FMYQTLERNL
360 370 380 390 400
RLMLAGSSQK NLNHVSSPSA SYTLSVPYAR LGWVMTSADL NQDGHGDLVV
410 420 430 440 450
GAPGYSHPGR FQIGRVYIIY GNDLGLPPID LDLDKEAHGI LEGFQPSGRF
460 470 480 490 500
GSALAVLDFN QDGLPDLAVG APSVGSGQLT YNGSVYVYYG SQQGRLSSSP
510 520 530 540 550
NVTISCKDTY CNLGWTLLAT DADGDGRHDL VISSPFAPGG GKQRGIVATF
560 570 580 590 600
YSHPRRNDKE LLTLEEADWK VNGEEDFSWF GYSLHGVTVA NRSLLLIGSP
610 620 630 640 650
TWKNVSRMAR SSHKKNQEEK SLGKVYGYFL PNRQSTITIS GDKAMGKLGT
660 670 680 690 700
SLSSGYVRVN GTLTQVLLVG APTHDDVSKM AFLTMTLHQG GATRMYELAP
710 720 730 740 750
EKTQPALLST FSGDRRFSRF GSVLHLTDLD DDGLDEIIMA APLRITDVTS
760 770 780 790 800
GLLGGEDGRV YIYNGMYTTL GDMTGKCKSW MTPCPEEKAQ YVLTSPEASS
810 820 830 840
RFGSSLVSVR SKGRNQVVVA AGRSSWGARL SGALHVYSFS SD
Length:842
Mass (Da):93,624
Last modified:March 1, 2002 - v1
Checksum:i2458B409EB550DD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC019146 mRNA. Translation: AAH19146.1.
AL589699, AL645533 Genomic DNA. Translation: CAI26087.1.
CH466561 Genomic DNA. Translation: EDL32466.1.
RefSeqiNP_032182.2. NM_008156.2.
XP_017170879.1. XM_017315390.1.
XP_017170880.1. XM_017315391.1.
UniGeneiMm.291831.

Genome annotation databases

EnsembliENSMUST00000021773; ENSMUSP00000021773; ENSMUSG00000021340.
GeneIDi14756.
KEGGimmu:14756.
UCSCiuc007pws.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ8VCU2_MOUSE
AccessioniPrimary (citable) accession number: Q8VCU2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: August 30, 2017
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported