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Protein

Trehalase

Gene

Treh

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Alpha,alpha-trehalose + H2O = beta-D-glucose + alpha-D-glucose.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase

Protein family/group databases

CAZyiGH37. Glycoside Hydrolase Family 37.

Names & Taxonomyi

Protein namesi
Recommended name:
TrehalaseUniRule annotation (EC:3.2.1.28UniRule annotation)
Alternative name(s):
Alpha-trehalose glucohydrolaseUniRule annotation
Gene namesi
Name:TrehImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1926230. Treh.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500431582921 – 541TrehalaseSequence analysisAdd BLAST521

Structurei

3D structure databases

ProteinModelPortaliQ8VCS8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 37 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0602. Eukaryota.
COG1626. LUCA.
HOGENOMiHOG000215465.
HOVERGENiHBG073526.

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
InterProiView protein in InterPro
IPR008928. 6-hairpin_glycosidase_sf.
IPR012341. 6hp_glycosidase-like_sf.
IPR001661. Glyco_hydro_37.
IPR018232. Glyco_hydro_37_CS.
PANTHERiPTHR23403. PTHR23403. 1 hit.
PfamiView protein in Pfam
PF01204. Trehalase. 1 hit.
PRINTSiPR00744. GLHYDRLASE37.
SUPFAMiSSF48208. SSF48208. 1 hit.
PROSITEiView protein in PROSITE
PS00928. TREHALASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8VCS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTWELHLLLL LGLGLRSQEA LPPPCERSTA MESSCTKFRW PSSTKMTSSL
60 70 80 90 100
WICHWPHLQM KSCRSSVSWP QSTTTASPRN SFRNLSRVTS SPWGRSCSPG
110 120 130 140 150
PLRTGRTALS SCRRSRMLIC VSGRRSYTRS GKSWERRDSY WVMEGLLLSE
160 170 180 190 200
MASTVKGMLQ NFLDLVKTYG HIPNGGRIYY LQRSQPPLLT LMMDRYVAHT
210 220 230 240 250
KDVAFLQENI GTLASELDFW TVNRTVSVVS GGQSYVLNRY YVPYGGPRPE
260 270 280 290 300
SYRKDAELAN SVPEGDRETL WAELKAGAES GWDFSSRWLV GGPDPDLLSS
310 320 330 340 350
IRTSKMVPAD LNAFLCQAEE LMSNFYSRLG NNTEATKYRN LRAQRLAAME
360 370 380 390 400
AVLWDEQKGA WFDYDLEKGK KNLEFYPSNL TPLWAGCFSD PSVADKALKY
410 420 430 440 450
LEDSKILTYQ YGIPTSLRNT GQQWDFPNAW APLQDLVIRG LAKSASPRTQ
460 470 480 490 500
EVAFQLAQNW IKTNFKVYSQ KSAMFEKYDI SNGGHPGGGG EYEVQEGFGW
510 520 530 540
TNGLALMLLD RYGDQLTSGT QLASLGPHCL VAALLLSLLL Q
Length:541
Mass (Da):60,840
Last modified:March 1, 2002 - v1
Checksum:i05A27E32C3A2875F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC019214 mRNA. Translation: AAH19214.1.
UniGeneiMm.45380.

Similar proteinsi

Entry informationi

Entry nameiQ8VCS8_MOUSE
AccessioniPrimary (citable) accession number: Q8VCS8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)