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Protein
Submitted name:

Ctsd protein

Gene

Ctsd

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl proteaseUniRule annotation, Hydrolase, Protease

Names & Taxonomyi

Protein namesi
Submitted name:
Ctsd proteinImported
Gene namesi
Name:CtsdImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88562. Ctsd.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PaxDbiQ8VCK2.
PeptideAtlasiQ8VCK2.
PRIDEiQ8VCK2.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000121203.

Structurei

3D structure databases

ProteinModelPortaliQ8VCK2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 212Peptidase A1InterPro annotationAdd BLAST212

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1339. Eukaryota.
ENOG410XNV7. LUCA.
HOVERGENiHBG000482.

Family and domain databases

Gene3Di2.40.70.10. 1 hit.
InterProiView protein in InterPro
IPR001461. Aspartic_peptidase_A1.
IPR001969. Aspartic_peptidase_AS.
IPR033144. Cathepsin_D.
IPR033121. PEPTIDASE_A1.
IPR021109. Peptidase_aspartic_dom.
PANTHERiPTHR13683. PTHR13683. 1 hit.
PTHR13683:SF487. PTHR13683:SF487. 1 hit.
PfamiView protein in Pfam
PF00026. Asp. 1 hit.
PRINTSiPR00792. PEPSIN.
SUPFAMiSSF50630. SSF50630. 1 hit.
PROSITEiView protein in PROSITE
PS00141. ASP_PROTEASE. 1 hit.
PS51767. PEPTIDASE_A1. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8VCK2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EGSPCPRCHH ISVNNVLPVF DNLMQQKLVD KNIFSFYLNR DPEGQPGGEL
60 70 80 90 100
MLGGTDSKYY HGELSYLNVT RKAYWQVHMD QLEVGNELTL CKGGCEAIVD
110 120 130 140 150
TGTSLLVGPV EEVKELQKAI GAVPLIQGEY MIPCEKVSSL PTVYLKLGGK
160 170 180 190 200
NYELHPDKYI LKVSQGGKTI CLSGFMGMDI PPPSGPLWIL GDVFIGSYYT
210
VFDRDNNRVG FANAVVL
Length:217
Mass (Da):23,932
Last modified:March 1, 2002 - v1
Checksum:i7DD42BB90D830F7B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC019682 mRNA. Translation: AAH19682.1.
UniGeneiMm.231395.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC019682 mRNA. Translation: AAH19682.1.
UniGeneiMm.231395.

3D structure databases

ProteinModelPortaliQ8VCK2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000121203.

Proteomic databases

PaxDbiQ8VCK2.
PeptideAtlasiQ8VCK2.
PRIDEiQ8VCK2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:88562. Ctsd.

Phylogenomic databases

eggNOGiKOG1339. Eukaryota.
ENOG410XNV7. LUCA.
HOVERGENiHBG000482.

Miscellaneous databases

ChiTaRSiCtsd. mouse.
SOURCEiSearch...

Family and domain databases

Gene3Di2.40.70.10. 1 hit.
InterProiView protein in InterPro
IPR001461. Aspartic_peptidase_A1.
IPR001969. Aspartic_peptidase_AS.
IPR033144. Cathepsin_D.
IPR033121. PEPTIDASE_A1.
IPR021109. Peptidase_aspartic_dom.
PANTHERiPTHR13683. PTHR13683. 1 hit.
PTHR13683:SF487. PTHR13683:SF487. 1 hit.
PfamiView protein in Pfam
PF00026. Asp. 1 hit.
PRINTSiPR00792. PEPSIN.
SUPFAMiSSF50630. SSF50630. 1 hit.
PROSITEiView protein in PROSITE
PS00141. ASP_PROTEASE. 1 hit.
PS51767. PEPTIDASE_A1. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8VCK2_MOUSE
AccessioniPrimary (citable) accession number: Q8VCK2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: May 10, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.