ID   MRGRF_MOUSE             Reviewed;         343 AA.
AC   Q8VCJ6; Q91ZB6;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-NOV-2009, entry version 63.
DE   RecName: Full=Mas-related G-protein coupled receptor member F;
DE            Short=Mas-related gene F protein;
GN   Name=Mrgprf; Synonyms=Mrgf;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Colon;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 25-343.
RC   STRAIN=C57BL/6;
RX   MEDLINE=21435808; PubMed=11551509; DOI=10.1016/S0092-8674(01)00483-4;
RA   Dong X., Han S.-K., Zylka M.J., Simon M.I., Anderson D.J.;
RT   "A diverse family of GPCRs expressed in specific subsets of
RT   nociceptive sensory neurons.";
RL   Cell 106:619-632(2001).
CC   -!- FUNCTION: Orphan receptor. May bind to a neuropeptide and may
CC       regulate nociceptor function and/or development, including the
CC       sensation or modulation of pain.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       Mas subfamily.
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DR   EMBL; BC019711; AAH19711.1; -; mRNA.
DR   EMBL; AY042211; AAK91802.1; -; Genomic_DNA.
DR   IPI; IPI00311019; -.
DR   RefSeq; NP_663354.1; -.
DR   UniGene; Mm.215151; -.
DR   STRING; Q8VCJ6; -.
DR   PRIDE; Q8VCJ6; -.
DR   Ensembl; ENSMUST00000033386; ENSMUSP00000033386; ENSMUSG00000031070; Mus musculus.
DR   GeneID; 211577; -.
DR   KEGG; mmu:211577; -.
DR   UCSC; uc009kqz.1; mouse.
DR   CTD; 211577; -.
DR   MGI; MGI:2384823; Mrgprf.
DR   HOGENOM; Q8VCJ6; -.
DR   HOVERGEN; Q8VCJ6; -.
DR   OMA; CPLMVLP; -.
DR   NextBio; 373289; -.
DR   ArrayExpress; Q8VCJ6; -.
DR   Bgee; Q8VCJ6; -.
DR   CleanEx; MM_MRGPRF; -.
DR   Genevestigator; Q8VCJ6; -.
DR   GermOnline; ENSMUSG00000031070; Mus musculus.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor protein signalin...; IEA:UniProtKB-KW.
DR   InterPro; IPR000276; 7TM_GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_supfam.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; G-protein coupled receptor; Glycoprotein; Membrane;
KW   Receptor; Transducer; Transmembrane.
FT   CHAIN         1    343       Mas-related G-protein coupled receptor
FT                                member F.
FT                                /FTId=PRO_0000069765.
FT   TOPO_DOM      1     44       Extracellular (Potential).
FT   TRANSMEM     45     66       1 (Potential).
FT   TOPO_DOM     67     82       Cytoplasmic (Potential).
FT   TRANSMEM     83    104       2 (Potential).
FT   TOPO_DOM    105    123       Extracellular (Potential).
FT   TRANSMEM    124    144       3 (Potential).
FT   TOPO_DOM    145    160       Cytoplasmic (Potential).
FT   TRANSMEM    161    181       4 (Potential).
FT   TOPO_DOM    182    198       Extracellular (Potential).
FT   TRANSMEM    199    220       5 (Potential).
FT   TOPO_DOM    221    241       Cytoplasmic (Potential).
FT   TRANSMEM    242    263       6 (Potential).
FT   TOPO_DOM    264    273       Extracellular (Potential).
FT   TRANSMEM    274    294       7 (Potential).
FT   TOPO_DOM    295    343       Cytoplasmic (Potential).
FT   CARBOHYD      4      4       N-linked (GlcNAc...) (Potential).
SQ   SEQUENCE   343 AA;  38523 MW;  358ED59587C9A317 CRC64;
     MAGNCSWEAH STNQNKMCPG MSEARELYSR GFLTIEQIAT LPPPAVTNYI FLLLCLCGLV
     GNGLVLWFFG FSIKRTPFSI YFLHLASADG MYLFSKAVIA LLNMGTFLGS FPDYIRRVSR
     IVGLCTFFTG VSLLPAISIE RCVSVIFPTW YWRRRPKRLS AGVCALLWML SFLVTSIHNY
     FCMFLGHEAP GTVCRNMDIA LGILLFFLFC PLMVLPCLAL ILHVECRARR RQRSAKLNHV
     VLAIVSVFLV SSIYLGIDWF LFWVFQIPAP FPEYVTDLCI CINSSAKPIV YFLAGRDKSQ
     RLWEPLRVVF QRALRDGAEP GDAASSTPNT VTMEMQCPSG NAS
//