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Reviewed, UniProtKB/Swiss-Prot Q8VCI0 (PLBL1_MOUSE)

Last modified November 24, 2009. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Putative phospholipase B-like 1
    EC=3.1.1.-
Alternative name(s):
    Phospholipase B domain-containing protein 1
    Lamina ancestor homolog 1
    LAMA-like protein 1
Gene names
Name: Plbd1
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

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Protein attributes

Sequence length550 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Function

Putative phospholipase By similarity.

Subcellular location

Secreted Potential.

Sequence similarities

Belongs to the phospholipase B-like family.

Sequence caution

The sequence BAE42780.1 differs from that shown. Reason: Frameshift at position 51.

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Ontologies

Keywords
   Biological processLipid degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionHydrolase
   PTMGlycoprotein
Gene Ontology (GO)
   Biological processlipid catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionhydrolase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3131 Potential
Chain32 – 550519Putative phospholipase B-like 1
PRO_0000286107

Amino acid modifications

Glycosylation721N-linked (GlcNAc...) (high mannose) Ref.3

Experimental info

Sequence conflict1271I → F in BAB22618. Ref.1
Sequence conflict5281E → D in BAB22618. Ref.1

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Sequences

Sequence LengthMass (Da)Tools
Q8VCI0-1 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: C89FC31C0D14B5F6

FASTA55062,998
        10         20         30         40         50         60 
MCHRSPGRSL RPPSPLLLLL PLLLQPPWAA GAASQSDPTG VHCATAYWSP ESKKVEIKTV 

        70         80         90        100        110        120 
LDKNGDAYGY YNDSIKTTGW GILEIRAGYG SQVLSNEIIM FLAGYLEGYL TALHMYDHFT 

       130        140        150        160        170        180 
NLYPQLIKNP SIVKKVQDFM EKQEMWTRQN IKAQKDDPFW RHTGYVVTQL DGLYLGAQKR 

       190        200        210        220        230        240 
ASEEKIKPMT MFQIQFLNAV GDLLDLIPSL SPTKSSSMMK FKIWEMGHCS ALIKVLPGFE 

       250        260        270        280        290        300 
NIYFAHSSWY TYAAMLRIYK HWDFNIKDKY TLSKRLSFSS YPGFLESLDD FYILSSGLIL 

       310        320        330        340        350        360 
LQTTNSVYNK TLLKQVVPKT LLAWQRVRVA NMMAEGGKEW AQIFSKHNSG TYNNQYMVLD 

       370        380        390        400        410        420 
LKKVTINRSL DKGTLYIVEQ IPTYVEYSDQ TNVLRKGYWA SYNIPFHKTI YNWSGYPLLV 

       430        440        450        460        470        480 
HKLGLDYSYD LAPRAKIFRR DQGNVTDMAS MKYIMRYNNY KEDPYSKGDP CSTICCREDL 

       490        500        510        520        530        540 
NGASPSPGGC YDTKVADIFL ASQYKAYAIS GPTVQDGLPP FNWNRFNETL HRGMPEVFDF 

       550 
NFVTMKPILS

« Hide

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References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J and NOD.
Tissue: Spleen.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Liver.
[3]"High throughput quantitative glycomics and glycoform-focused proteomics of murine dermis and epidermis."
Uematsu R., Furukawa J., Nakagawa H., Shinohara Y., Deguchi K., Monde K., Nishimura S.
Mol. Cell. Proteomics 4:1977-1989(2005) [PubMed: 16170054] [Abstract]
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-72, MASS SPECTROMETRY.
Tissue: Epidermis.
+Additional computationally mapped references.

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Cross-references

Sequence databases

AK003169 mRNA. Translation: BAB22618.1.
AK172021 mRNA. Translation: BAE42780.1. Frameshift.
BC019793 mRNA. Translation: AAH19793.1.
IPIIPI00471081.
RefSeqNP_080082.1.
UniGeneMm.3311

3D structure databases

ModBaseSearch...

PTM databases

PhosphoSiteQ8VCI0.

Proteomic databases

PRIDEQ8VCI0.

Genome annotation databases

EnsemblENSMUST00000032336; ENSMUSP00000032336; ENSMUSG00000030214; Mus musculus. [Genome view]
GeneID66857.
KEGGmmu:66857.

Organism-specific databases

CTD66857.
MGIMGI:1914107. 1100001H23Rik.

Phylogenomic databases

HOVERGENQ8VCI0.

Gene expression databases

ArrayExpressQ8VCI0.
BgeeQ8VCI0.
CleanExMM_1100001H23RIK.
GenevestigatorQ8VCI0.

Family and domain databases

InterProIPR007000. Phospholipase_B-like.
[Graphical view]
PANTHERPTHR12370. Laminin_A. 1 hit.
PfamPF04916. Phospholip_B. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio322835.
SOURCESearch...

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Entry information

Entry namePLBL1_MOUSE
AccessionPrimary (citable) accession number: Q8VCI0
Secondary accession number(s): Q3TA89, Q9D1S0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: March 1, 2002
Last modified: November 24, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

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Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents