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Q8VCE3

- Q8VCE3_MOUSE

UniProt

Q8VCE3 - Q8VCE3_MOUSE

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Protein
Submitted name:

Desmoglein-2

Gene

Dsg2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro

GO - Biological processi

  1. homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Cell adhesionSAAS annotation

Keywords - Ligandi

CalciumUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Desmoglein-2Imported
Submitted name:
Dsg2 proteinImported
Gene namesi
Name:Dsg2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 18

Organism-specific databases

MGIiMGI:1196466. Dsg2.

Subcellular locationi

GO - Cellular componenti

  1. desmosome Source: MGI
  2. integral component of membrane Source: UniProtKB-KW
  3. plasma membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

GenevestigatoriQ8VCE3.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000057096.

Family & Domainsi

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118906.
HOGENOMiHOG000146465.
HOVERGENiHBG067346.

Family and domain databases

Gene3Di2.60.40.60. 2 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR009122. Desmosomal_cadherin.
[Graphical view]
PANTHERiPTHR24025. PTHR24025. 1 hit.
PfamiPF00028. Cadherin. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 2 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 2 hits.
PROSITEiPS00232. CADHERIN_1. 2 hits.
PS50268. CADHERIN_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VCE3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MARSPGDRCA LLLLVQLLAV VCLDFGNGLH LEVFSPRNEG KPFPKHTHLV
60 70 80 90 100
RQKRAWITAP VALREGEDLS RKNPIAKIHS DLAEEKGIKI TYKYTGKGIT
110 120 130 140 150
EPPFGIFVFD RNTGELNITS ILDREETPYF LLTGYALDSR GNNLEKPLEL
160 170 180 190 200
RIKVLDINDN EPVFTQEVFV GSIEELSAAH TLVMKITATD ADDPETLNAK
210 220 230 240 250
VSYRIVSQEP ANSHMFYLNK DTGEIYTTSF TLDREEHSSY SLTVEARDGN
260 270 280 290
GQITDKPVQQ AQVQIRILDV NDNIPVVENK MVTQFYSRLT IS
Length:292
Mass (Da):32,850
Last modified:March 1, 2002 - v1
Checksum:i7C2E26D76FA6FEAF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132091 Genomic DNA. No translation available.
BC020144 mRNA. Translation: AAH20144.1.
UniGeneiMm.345891.

Genome annotation databases

EnsembliENSMUST00000121837; ENSMUSP00000113029; ENSMUSG00000044393.
UCSCiuc008eeq.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132091 Genomic DNA. No translation available.
BC020144 mRNA. Translation: AAH20144.1 .
UniGenei Mm.345891.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000057096.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000121837 ; ENSMUSP00000113029 ; ENSMUSG00000044393 .
UCSCi uc008eeq.1. mouse.

Organism-specific databases

MGIi MGI:1196466. Dsg2.

Phylogenomic databases

GeneTreei ENSGT00760000118906.
HOGENOMi HOG000146465.
HOVERGENi HBG067346.

Miscellaneous databases

ChiTaRSi Dsg2. mouse.
SOURCEi Search...

Gene expression databases

Genevestigatori Q8VCE3.

Family and domain databases

Gene3Di 2.60.40.60. 2 hits.
InterProi IPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR009122. Desmosomal_cadherin.
[Graphical view ]
PANTHERi PTHR24025. PTHR24025. 1 hit.
Pfami PF00028. Cadherin. 1 hit.
[Graphical view ]
PRINTSi PR00205. CADHERIN.
SMARTi SM00112. CA. 2 hits.
[Graphical view ]
SUPFAMi SSF49313. SSF49313. 2 hits.
PROSITEi PS00232. CADHERIN_1. 2 hits.
PS50268. CADHERIN_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Mix FVB/NImported.
    Tissue: Mammary tumor. WAP-TGF alpha model. 7 months oldImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ8VCE3_MOUSE
AccessioniPrimary (citable) accession number: Q8VCE3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: November 26, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3