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Protein

Mannosyltransferase

Gene

Alg12

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseUniRule annotationImported, Transferase

Protein family/group databases

CAZyiGT22. Glycosyltransferase Family 22.

Names & Taxonomyi

Protein namesi
Recommended name:
MannosyltransferaseUniRule annotation (EC:2.4.1.-UniRule annotation)
Gene namesi
Name:Alg12Imported
ORF Names:mCG_7282Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:2385025. Alg12.

Subcellular locationi

  • Endoplasmic reticulum membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3322HelicalUniRule annotationAdd
BLAST
Transmembranei69 – 8618HelicalUniRule annotationAdd
BLAST
Transmembranei98 – 11619HelicalUniRule annotationAdd
BLAST
Transmembranei122 – 14120HelicalUniRule annotationAdd
BLAST
Transmembranei148 – 16619HelicalUniRule annotationAdd
BLAST
Transmembranei172 – 19827HelicalUniRule annotationAdd
BLAST
Transmembranei210 – 22920HelicalUniRule annotationAdd
BLAST
Transmembranei241 – 26424HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000035845.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000123935.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 22 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG2516. Eukaryota.
ENOG410XR38. LUCA.
GeneTreeiENSGT00550000075005.
HOGENOMiHOG000265945.
HOVERGENiHBG050486.

Family and domain databases

InterProiIPR005599. GPI_mannosylTrfase.
[Graphical view]
PANTHERiPTHR22760. PTHR22760. 1 hit.
PfamiPF03901. Glyco_transf_22. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VCA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGKKSSGKR SWPLLGLLVT VATIHLVICP YTKVEESFNL QATHDLLYHQ
60 70 80 90 100
LDIDKYDHHE FPGVVPRTFL GPLVIAAFSS PVVYVLSLLE VSKFYSQLIV
110 120 130 140 150
RGVLGLGVIS GLWTLQKEVR QQFGATVAVM FCWISATQFH LMFYCTRTLP
160 170 180 190 200
NVLALAVVLP ALTAWLQRRW ALFVWLSAFV IIGFRAELAM LLGIALLLTL
210 220 230 240 250
YQRRLTVARV LRHAIPAGLL CLGKLASLVC LLNKKSWPYK VRAMLVTGHI
260 270 280 290 300
LVNVAYTATS LYVSHFNYPG GVAMQQLHEL VPPQTDVLLH IDVAAAQTGV
310 320 330 340 350
SRFLQVNDDW RYDKSEDVGA AAMLNYTHIL MEAVPGHPAL YRDTHRVLAS
360 370 380
IEGTTGISLN LMKLPPFDVN LQTKLVLLER LLRPA
Length:385
Mass (Da):42,917
Last modified:March 1, 2002 - v1
Checksum:iAACA8C23647B81ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC117700 Genomic DNA. No translation available.
BC021379 mRNA. Translation: AAH21379.1.
CH466550 Genomic DNA. Translation: EDL04397.1.
RefSeqiNP_663452.1. NM_145477.2.
UniGeneiMm.41512.

Genome annotation databases

EnsembliENSMUST00000043087; ENSMUSP00000043480; ENSMUSG00000035845.
GeneIDi223774.
UCSCiuc007xen.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC117700 Genomic DNA. No translation available.
BC021379 mRNA. Translation: AAH21379.1.
CH466550 Genomic DNA. Translation: EDL04397.1.
RefSeqiNP_663452.1. NM_145477.2.
UniGeneiMm.41512.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000123935.

Protein family/group databases

CAZyiGT22. Glycosyltransferase Family 22.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000043087; ENSMUSP00000043480; ENSMUSG00000035845.
GeneIDi223774.
UCSCiuc007xen.2. mouse.

Organism-specific databases

CTDi79087.
MGIiMGI:2385025. Alg12.

Phylogenomic databases

eggNOGiKOG2516. Eukaryota.
ENOG410XR38. LUCA.
GeneTreeiENSGT00550000075005.
HOGENOMiHOG000265945.
HOVERGENiHBG050486.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000035845.

Family and domain databases

InterProiIPR005599. GPI_mannosylTrfase.
[Graphical view]
PANTHERiPTHR22760. PTHR22760. 1 hit.
PfamiPF03901. Glyco_transf_22. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8VCA2_MOUSE
AccessioniPrimary (citable) accession number: Q8VCA2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: September 7, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.