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Protein

RNA-binding motif, single-stranded-interacting protein 2

Gene

Rbms2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding motif, single-stranded-interacting protein 2
Gene namesi
Name:Rbms2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1861776. Rbms2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000818011 – 383RNA-binding motif, single-stranded-interacting protein 2Add BLAST383

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1
Modified residuei108PhosphoserineBy similarity1
Modified residuei287PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ8VC70.
PaxDbiQ8VC70.
PeptideAtlasiQ8VC70.
PRIDEiQ8VC70.

PTM databases

iPTMnetiQ8VC70.
PhosphoSitePlusiQ8VC70.

Expressioni

Gene expression databases

BgeeiENSMUSG00000040043.
ExpressionAtlasiQ8VC70. baseline and differential.
GenevisibleiQ8VC70. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000089664.

Structurei

3D structure databases

ProteinModelPortaliQ8VC70.
SMRiQ8VC70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 131RRM 1PROSITE-ProRule annotationAdd BLAST74
Domaini137 – 222RRM 2PROSITE-ProRule annotationAdd BLAST86

Sequence similaritiesi

Contains 2 RRM (RNA recognition motif) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG4733. Eukaryota.
ENOG410XRB5. LUCA.
GeneTreeiENSGT00760000118913.
HOGENOMiHOG000008467.
HOVERGENiHBG053108.
InParanoidiQ8VC70.
OMAiTPSDHGV.
OrthoDBiEOG091G0FXS.
PhylomeDBiQ8VC70.
TreeFamiTF314644.

Family and domain databases

Gene3Di3.30.70.330. 2 hits.
InterProiIPR002343. Hud_Sxl_RNA.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 2 hits.
[Graphical view]
PRINTSiPR00961. HUDSXLRNA.
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8VC70-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLSVTSRPG ISTFGYNKNN KKLYVAQQMA PPSPRNSTPN SSGGGGGGSG
60 70 80 90 100
GNDQLSKTNL YIRGLQPGTT DQDLVKLCQP YGKIVSTKAI LDKTTNKCKG
110 120 130 140 150
YGFVDFDSPS SAQKAVTALK ASGVQAQMAK QQEQDPTNLY ISNLPLSMDE
160 170 180 190 200
QELEGMLKPF GQVISTRILR DTSGASRGVG FARMESTEKC EAIITHFNGK
210 220 230 240 250
YIKTPPGVAA PSDPLLCKFA DGGPKKRQSQ GRYVQNGRAW PRNGDMGGMA
260 270 280 290 300
LTYDPTAALQ NGFYAAPYSI AHSRMLAQSA LAPYLPSPVS SYQGSVLTPG
310 320 330 340 350
MDHPLSLQPA SMMGPLTQQL GHLSLNSLGT FMPAAAAMHG AYISQYPAVP
360 370 380
SSSVSAEESN GQQNQLAVEP PSDHGVYPFQ FSK
Length:383
Mass (Da):40,724
Last modified:March 1, 2002 - v1
Checksum:i2CD11874A92CEBEF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC021627 mRNA. Translation: AAH21627.1.
AK054482 mRNA. Translation: BAC35797.1.
CCDSiCCDS24261.1.
RefSeqiNP_001034169.1. NM_001039080.1.
NP_062685.2. NM_019711.2.
XP_006513962.1. XM_006513899.2.
XP_006513963.1. XM_006513900.2.
UniGeneiMm.42247.

Genome annotation databases

EnsembliENSMUST00000092033; ENSMUSP00000089664; ENSMUSG00000040043.
GeneIDi56516.
KEGGimmu:56516.
UCSCiuc007hlm.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC021627 mRNA. Translation: AAH21627.1.
AK054482 mRNA. Translation: BAC35797.1.
CCDSiCCDS24261.1.
RefSeqiNP_001034169.1. NM_001039080.1.
NP_062685.2. NM_019711.2.
XP_006513962.1. XM_006513899.2.
XP_006513963.1. XM_006513900.2.
UniGeneiMm.42247.

3D structure databases

ProteinModelPortaliQ8VC70.
SMRiQ8VC70.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000089664.

PTM databases

iPTMnetiQ8VC70.
PhosphoSitePlusiQ8VC70.

Proteomic databases

MaxQBiQ8VC70.
PaxDbiQ8VC70.
PeptideAtlasiQ8VC70.
PRIDEiQ8VC70.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000092033; ENSMUSP00000089664; ENSMUSG00000040043.
GeneIDi56516.
KEGGimmu:56516.
UCSCiuc007hlm.1. mouse.

Organism-specific databases

CTDi5939.
MGIiMGI:1861776. Rbms2.

Phylogenomic databases

eggNOGiKOG4733. Eukaryota.
ENOG410XRB5. LUCA.
GeneTreeiENSGT00760000118913.
HOGENOMiHOG000008467.
HOVERGENiHBG053108.
InParanoidiQ8VC70.
OMAiTPSDHGV.
OrthoDBiEOG091G0FXS.
PhylomeDBiQ8VC70.
TreeFamiTF314644.

Miscellaneous databases

ChiTaRSiRbms2. mouse.
PROiQ8VC70.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000040043.
ExpressionAtlasiQ8VC70. baseline and differential.
GenevisibleiQ8VC70. MM.

Family and domain databases

Gene3Di3.30.70.330. 2 hits.
InterProiIPR002343. Hud_Sxl_RNA.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 2 hits.
[Graphical view]
PRINTSiPR00961. HUDSXLRNA.
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRBMS2_MOUSE
AccessioniPrimary (citable) accession number: Q8VC70
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: March 1, 2002
Last modified: November 2, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.