Q8VBX6 (MPDZ_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Multiple PDZ domain protein

Alternative name(s):
Multi-PDZ domain protein 1

Gene names

Name:	Mpdz
Synonyms:	Mupp1

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	2055 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses By similarity.
Subunit structure	Interacts with CLDN5, DLG4, GRIN1, SYNGAP1, CAMK2A and CAMK2B, HTR2A, HTR2B, HTR2C, PLEKHA1/TAPP1 and PLEKHA2/TAPP2 By similarity. Interacts with F11R/JAM, CLDN1, NG2, CXADR, CRB1, MPP4 and MPP5. Interacts with the adenovirus type 9 E4-ORF1 oncoprotein. Ref.7 Ref.8 Ref.9 Ref.10 Ref.13 Ref.14
Subcellular location	Cell membrane; Peripheral membrane protein; Cytoplasmic side. Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction › synapse › postsynaptic cell membrane › postsynaptic density. Cell projection › dendrite. Cell junction › tight junction By similarity. Cell junction › synapse. Cell junction › synapse › synaptosome By similarity. Note: Colocalizes with HTR2C on the apical membrane of epithelial choroid plexus cells. Highly enriched in postsynaptic densities (PSD). Localized to punctae on dendrites of hippocampal neurons and colocalizes with the synaptic marker DLG4. Enriched at the tight junctions of epithelial cells. Association to the tight junctions depends on CXADR By similarity. In the retina, localizes to the sub-apical region adjacent to the adherens junction complex at the outer limiting membrane. Localized mainly in the Schmidt-Lanterman incisures of myelinating Schwann cells. Ref.10 Ref.11 Ref.14
Tissue specificity	In the brain, it is strongly expressed in the choroid plexus. Within the hippocampal formation, strongest expression was seen in the soma of CA1-4 pyramidal cells. Expressed in most neocortical regions with the strongest expression in piriform cortex and amygdaloid nuclei but also detected in the subiculum and olfactory bulb. In the cerebellum, the highest level of expression was found in Purkinje cells. Moderately expressed in the granular layer and molecular layer. Expressed in the pontine nuclei, parts of spinal trigeminal nuclei, and the principal sensory trigeminal nuclei of the metencephalon. Expressed in all thalamic and hypothalamic nuclei, and the substantia nigra (at protein level). Ubiquitously expressed. Ref.7 Ref.12
Domain	The PDZ domain 2 mainly binds CAMK2A and CAMK2B. The PDZ domains 7 and 10 bind the Ad9 E4-ORF1 oncoprotein. The PDZ domain 10 binds the C-terminal PDZ-binding motif of HTR2C. The PDZ domains 10 and 13 bind PLEKHA1 and PLEKHA2. The PDZ domain 13 binds SYNGAP1 By similarity. The PDZ domain 1 binds NG2. The PDZ domain 9 binds F11R. The PDZ domain 10 binds the C-terminus of CLDN1 and KIT. The PDZ domain 13 binds CXADR. Ref.10 Ref.13
Sequence similarities	Contains 1 L27 domain. Contains 13 PDZ (DHR) domains.
Sequence caution	The sequence BAC27346.1 differs from that shown. Reason: Erroneous initiation. The sequence BAC34766.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cell junction Cell membrane Cell projection Membrane Postsynaptic cell membrane Synapse Synaptosome Tight junction
Coding sequence diversity	Alternative splicing
Domain	Repeat
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from direct assay Ref.10. Source: MGI myelination Inferred from electronic annotation. Source: Compara
Cellular_component	Schmidt-Lanterman incisure Inferred from direct assay PubMed 20237282. Source: BHF-UCL apical plasma membrane Inferred from direct assay PubMed 17397395. Source: MGI apicolateral plasma membrane Inferred from electronic annotation. Source: Compara cytoplasmic vesicle Inferred from direct assay PubMed 17397395. Source: MGI postsynaptic density Inferred from electronic annotation. Source: UniProtKB-SubCell postsynaptic membrane Inferred from electronic annotation. Source: UniProtKB-KW tight junction Inferred from direct assay Ref.10PubMed 17397395. Source: MGI
Complete GO annotation...

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8VBX6-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8VBX6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1236-1268: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q8VBX6-3)

The sequence of this isoform differs from the canonical sequence as follows:
     2054-2055: LS → SLEVTARVEAAQPLAPLLL

Note: No experimental confirmation available.

Isoform 4 (identifier: Q8VBX6-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1714-1714: Q → QLQ

Note: No experimental confirmation available.

Isoform 5 (identifier: Q8VBX6-5)

The sequence of this isoform differs from the canonical sequence as follows:
     63-87: NIATLATAAADHAHTPQFSSAVISN → GWHHPQRPSRCSKDLVRKGSCFSTG
     88-2055: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 2055	2055	Multiple PDZ domain protein		PRO_0000094595
Regions
	Domain	1 – 63	63	L27
	Domain	138 – 225	88	PDZ 1
	Domain	258 – 338	81	PDZ 2
	Domain	378 – 464	87	PDZ 3
	Domain	546 – 627	82	PDZ 4
	Domain	693 – 779	87	PDZ 5
	Domain	996 – 1077	82	PDZ 6
	Domain	1139 – 1231	93	PDZ 7
	Domain	1338 – 1421	84	PDZ 8
	Domain	1471 – 1552	82	PDZ 9
	Domain	1614 – 1697	84	PDZ 10
	Domain	1710 – 1792	83	PDZ 11
	Domain	1847 – 1933	87	PDZ 12
	Domain	1972 – 2055	84	PDZ 13
Amino acid modifications
	Modified residue	231	1	Phosphoserine By similarity
Natural variations
	Alternative sequence	63 – 87	25	NIATL…AVISN → GWHHPQRPSRCSKDLVRKGS CFSTG in isoform 5.		VSP_014199
	Alternative sequence	88 – 2055	1968	Missing in isoform 5.		VSP_014200
	Alternative sequence	1236 – 1268	33	Missing in isoform 2.		VSP_014201
	Alternative sequence	1714	1	Q → QLQ in isoform 4.		VSP_014202
	Alternative sequence	2054 – 2055	2	LS → SLEVTARVEAAQPLAPLLL in isoform 3.		VSP_014203
	Natural variant	541	1	N → S in strain: DBA/2J and DBA1/J. Ref.2
	Natural variant	691	1	G → V in strain: DBA/2J, DBA1/J, CE/J, A/HeJ, BALB/cJ, C57Br/cdJ, C57L/J, WSP2 and 129/J. Ref.2
	Natural variant	801	1	H → R in strain: DBA/2J, DBA1/J, CE/J, A/HeJ, BALB/cJ, C57Br/cdJ, C57L/J, WSP2 and 129/J. Ref.2
	Natural variant	859	1	T → A in strain: DBA/2J, DBA1/J, CE/J, A/HeJ, BALB/cJ, C57Br/cdJ, C57L/J, WSP2 and 129/J. Ref.2
	Natural variant	880	1	S → N in strain: DBA/2J, DBA1/J, CE/J, A/HeJ, BALB/cJ, C57Br/cdJ, C57L/J, WSP2 and 129/J. Ref.2
	Natural variant	914	1	R → S in strain: DBA/2J, DBA1/J, CE/J, A/HeJ, BALB/cJ, C57Br/cdJ, C57L/J, WSP2 and 129/J. Ref.2
	Natural variant	977	1	A → V in strain: DBA/2J, DBA1/J, CE/J, A/HeJ, BALB/cJ, C57Br/cdJ, C57L/J, WSP2 and 129/J. Ref.2
	Natural variant	1338	1	V → M in strain: DBA/2J, DBA1/J, CE/J, A/HeJ, BALB/cJ, C57Br/cdJ, C57L/J, WSP2 and 129/J. Ref.2
	Natural variant	1433	1	I → N in strain: DBA/2J, DBA1/J, CE/J, A/HeJ, BALB/cJ, C57Br/cdJ, C57L/J, WSP2 and 129/J. Ref.2
	Natural variant	1767	1	H → N in strain: DBA/2J, DBA1/J, CE/J, A/HeJ, BALB/cJ, C57Br/cdJ, C57L/J, WSP2 and 129/J. Ref.2
Experimental info
	Sequence conflict	583	1	S → N in CAA10523. Ref.1
	Sequence conflict	588	1	S → N in CAA10523. Ref.1
	Sequence conflict	871	1	P → S in CAA10523. Ref.1
	Sequence conflict	909 – 910	2	PP → SS in CAA10523. Ref.1
	Sequence conflict	914 – 919	6	RPAPTS → KPTPTF in CAA10523. Ref.1
	Sequence conflict	932	1	V → G in CAA10523. Ref.1
	Sequence conflict	937 – 938	2	EC → QW in CAA10523. Ref.1
	Sequence conflict	952	1	S → N in CAA10523. Ref.1
	Sequence conflict	956	1	S → F in CAA10523. Ref.1
	Sequence conflict	960	1	P → S in CAA10523. Ref.1
	Sequence conflict	963	1	P → A in CAA10523. Ref.1
	Sequence conflict	967	1	Q → P in CAA10523. Ref.1
	Sequence conflict	974 – 975	2	SS → TF in CAA10523. Ref.1
	Sequence conflict	984	1	N → T in CAA10523. Ref.1
	Sequence conflict	996	1	T → P in CAA10523. Ref.1
	Sequence conflict	1532	1	K → N in AAB57835. Ref.6
	Sequence conflict	1547	1	T → I in AAB57835. Ref.6
	Sequence conflict	1589	1	T → P in CAA10523. Ref.1
	Sequence conflict	1616 – 1617	2	EI → GV in AAB57835. Ref.6
	Sequence conflict	1691	1	L → V in AAB57835. Ref.6
	Sequence conflict	1844	1	G → R in AAB57835. Ref.6
	Sequence conflict	1914	1	A → V in AAH61504. Ref.5
	Sequence conflict	1968	1	P → S in CAA10523. Ref.1
	Sequence conflict	1983 – 1985	3	GFS → SFN in CAA10523. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified June 21, 2005. Version 2. Checksum: 26EA94B814214B69	FASTA	2,055	218,711
	10 20 30 40 50 60 MLETIDKNRA LQAAERLQSK LKERGDVANE DKLSLLKSVL QSPLFSQILN LQTSLQQLKD 70 80 90 100 110 120 QVNIATLATA AADHAHTPQF SSAVISNLQS ESLLLSPNHG NLEALPGPGA PAVMDGKPTC 130 140 150 160 170 180 DELDQLIKNM AQGRHVEIFE LLKPPCGGLG FSVVGLRSEN RGELGIFVQE IQEGSVAHRD 190 200 210 220 230 240 GRLKETDQIL AINGQVLDQT ITHQQAISIL QKAKDTVQLV IARGSLPPVS SPRISRSPSA 250 260 270 280 290 300 ASTISAHSNP MHWQHVETIE LVNDGSGLGF GIIGGKATGV IVKTILPGGV ADQHGRLCSG 310 320 330 340 350 360 DHILKIGDTD LAGMSSEQVA QVLRQCGNRV KLMIARGAVE ETPASSSLGI TLSSSTSSTS 370 380 390 400 410 420 EMRVDASTQK NDESETFDVE LTKNVQGLGI TIAGYIGDKK LEPSGIFVKS ITKSSAVEHD 430 440 450 460 470 480 GRIQIGDQII AVDGTNLQGF TNQQAVEVLR HTGQTVRLTL MRKGASQEAE LTSRGDTAKD 490 500 510 520 530 540 VDLPAENCEK DEESLSLKRN TSILPIEEEG FPLLSAELEE AEDVQQEAAL LTKWQRIMGI 550 560 570 580 590 600 NYEIVVAHVS KFSENSGLGI SLEATVGHHF IRSVLPEGPV GHSGKLFSGD ELLEVNGINL 610 620 630 640 650 660 LGENHQDVVN ILKELPIDVT MVCCRRTVPP IALSEMDSLD INDLELTEKP HIDLGEFIGS 670 680 690 700 710 720 SETEDPMLAM SDVDQNAEEI QTPLAMWEAG GQSIELEKGS RGLGFSILDY QDPIDPANTV 730 740 750 760 770 780 IVIRSLVPGG IAEKDGRLFP GDRLMFVNDI NLENSTLEEA VEALKGAPSG MVRIGVAKPL 790 800 810 820 830 840 PLSPEEGYVS AKEDAFLCSP HACKESGLSD KALFRADLAL IDTPDAESIA ESRFESQFSP 850 860 870 880 890 900 DNDSVYSTQA SIFSLHDGTC SDGMNYGPSL PSSPPKDVTS SSEVVLGLHL SLEELYTQNL 910 920 930 940 950 960 LQRQHAGSPP TDMRPAPTSG FPISDYTTTN AVEQKYECAN PVAWPHSQLP SSLSTSELAP 970 980 990 1000 1010 1020 ALPAVAQKYL TDQSSLASDA ESVNLQSMSQ EAFERTVTIA KGSSSLGMTV SANKDGLGVI 1030 1040 1050 1060 1070 1080 VRSIIHGGAI SRDGRIAVGD CILSINEEST ISLTNAQARA MLRRHSLIGP DIKITYVPAE 1090 1100 1110 1120 1130 1140 HLEEFRVSFG QQAGGIMALD IFSSYTGRDI PELPEREEGE GEESELQNAA YSSWSQPRRV 1150 1160 1170 1180 1190 1200 ELWREPSKSL GISIVGGRGM GSRLSNGEVM RGIFIKHVLE DSPAGKNGTL KPGDRIIEVD 1210 1220 1230 1240 1250 1260 GMDLRDASHE QAVEAIRKAG NPVVFMVQSI INRPRKSPLP SLPHSLYPKY SFSSTNPFAD 1270 1280 1290 1300 1310 1320 SLQLTTDQAP SQSESETEKP ALCNVPPSSP SVFSEMGSDC AQPSATAVSE DEDKEDEFGY 1330 1340 1350 1360 1370 1380 SWKNIQERYG SLTGQLHVIE LEKGQSGLGL SLAGNKDRTR MSVFIVGIDP TGAAGRDGRL 1390 1400 1410 1420 1430 1440 QIADELLEIN GQILYGRSHQ NASSIIKCAP SKVKIIFIRN ADAVNQMAVC PGIAADSPSS 1450 1460 1470 1480 1490 1500 TSDSPQNKEV EPCSTTSASA ADLSSLTDVY QLELPKDQGG LGIAICEEDT INGVMIESLT 1510 1520 1530 1540 1550 1560 EHGGAAKDGR LKPGDHILAV DDEVVAGCPV EKFISLLKTA KATVKLTVRA ENPACPAVPS 1570 1580 1590 1600 1610 1620 SAVTVSGERK DNSQTPAVPA PDLEPIPSTS RSSTPAVFAS DPATCPIIPG CETTIEISKG 1630 1640 1650 1660 1670 1680 QTGLGLSIVG GSDTLLGAII IHEVYEEGAA CKDGRLWAGD QILEVNGIDL RKATHDEAIN 1690 1700 1710 1720 1730 1740 VLRQTPQRVR LTLYRDEAPY KEEDVCDTFT IELQKRPGKG LGLSIVGKRN DTGVFVSDIV 1750 1760 1770 1780 1790 1800 KGGIADADGR LMQGDQILMV NGEDVRHATQ EAVAALLKCS LGAVTLEVGR VKAAPFHSER 1810 1820 1830 1840 1850 1860 RPSQSSQVSE SSLSSFTPPL SGINTSESLE SNSKKNALAS EIQGLRTVEI KKGPADSLGL 1870 1880 1890 1900 1910 1920 SIAGGVGSPL GDVPIFIAMM HPNGVAAQTQ KLRVGDRIVT ICGTSTDGMT HTQAVNLMKN 1930 1940 1950 1960 1970 1980 ASGSIEVQVV AGGDVSVVTG HQQELANPCL AFTGLTSSSI FPDDLGPPQS KTITLDRGPD 1990 2000 2010 2020 2030 2040 GLGFSIVGGY GSPHGDLPIY VKTVFAKGAA AEDGRLKRGD QIIAVNGQSL EGVTHEEAVA 2050 ILKRTKGTVT LMVLS
	Isoform 2 [UniParc]. Checksum: 1B5D7BF3FFA7B4BA	FASTA	2,022	215,061
	10 20 30 40 50 60 MLETIDKNRA LQAAERLQSK LKERGDVANE DKLSLLKSVL QSPLFSQILN LQTSLQQLKD 70 80 90 100 110 120 QVNIATLATA AADHAHTPQF SSAVISNLQS ESLLLSPNHG NLEALPGPGA PAVMDGKPTC 130 140 150 160 170 180 DELDQLIKNM AQGRHVEIFE LLKPPCGGLG FSVVGLRSEN RGELGIFVQE IQEGSVAHRD 190 200 210 220 230 240 GRLKETDQIL AINGQVLDQT ITHQQAISIL QKAKDTVQLV IARGSLPPVS SPRISRSPSA 250 260 270 280 290 300 ASTISAHSNP MHWQHVETIE LVNDGSGLGF GIIGGKATGV IVKTILPGGV ADQHGRLCSG 310 320 330 340 350 360 DHILKIGDTD LAGMSSEQVA QVLRQCGNRV KLMIARGAVE ETPASSSLGI TLSSSTSSTS 370 380 390 400 410 420 EMRVDASTQK NDESETFDVE LTKNVQGLGI TIAGYIGDKK LEPSGIFVKS ITKSSAVEHD 430 440 450 460 470 480 GRIQIGDQII AVDGTNLQGF TNQQAVEVLR HTGQTVRLTL MRKGASQEAE LTSRGDTAKD 490 500 510 520 530 540 VDLPAENCEK DEESLSLKRN TSILPIEEEG FPLLSAELEE AEDVQQEAAL LTKWQRIMGI 550 560 570 580 590 600 NYEIVVAHVS KFSENSGLGI SLEATVGHHF IRSVLPEGPV GHSGKLFSGD ELLEVNGINL 610 620 630 640 650 660 LGENHQDVVN ILKELPIDVT MVCCRRTVPP IALSEMDSLD INDLELTEKP HIDLGEFIGS 670 680 690 700 710 720 SETEDPMLAM SDVDQNAEEI QTPLAMWEAG GQSIELEKGS RGLGFSILDY QDPIDPANTV 730 740 750 760 770 780 IVIRSLVPGG IAEKDGRLFP GDRLMFVNDI NLENSTLEEA VEALKGAPSG MVRIGVAKPL 790 800 810 820 830 840 PLSPEEGYVS AKEDAFLCSP HACKESGLSD KALFRADLAL IDTPDAESIA ESRFESQFSP 850 860 870 880 890 900 DNDSVYSTQA SIFSLHDGTC SDGMNYGPSL PSSPPKDVTS SSEVVLGLHL SLEELYTQNL 910 920 930 940 950 960 LQRQHAGSPP TDMRPAPTSG FPISDYTTTN AVEQKYECAN PVAWPHSQLP SSLSTSELAP 970 980 990 1000 1010 1020 ALPAVAQKYL TDQSSLASDA ESVNLQSMSQ EAFERTVTIA KGSSSLGMTV SANKDGLGVI 1030 1040 1050 1060 1070 1080 VRSIIHGGAI SRDGRIAVGD CILSINEEST ISLTNAQARA MLRRHSLIGP DIKITYVPAE 1090 1100 1110 1120 1130 1140 HLEEFRVSFG QQAGGIMALD IFSSYTGRDI PELPEREEGE GEESELQNAA YSSWSQPRRV 1150 1160 1170 1180 1190 1200 ELWREPSKSL GISIVGGRGM GSRLSNGEVM RGIFIKHVLE DSPAGKNGTL KPGDRIIEVD 1210 1220 1230 1240 1250 1260 GMDLRDASHE QAVEAIRKAG NPVVFMVQSI INRPRAPSQS ESETEKPALC NVPPSSPSVF 1270 1280 1290 1300 1310 1320 SEMGSDCAQP SATAVSEDED KEDEFGYSWK NIQERYGSLT GQLHVIELEK GQSGLGLSLA 1330 1340 1350 1360 1370 1380 GNKDRTRMSV FIVGIDPTGA AGRDGRLQIA DELLEINGQI LYGRSHQNAS SIIKCAPSKV 1390 1400 1410 1420 1430 1440 KIIFIRNADA VNQMAVCPGI AADSPSSTSD SPQNKEVEPC STTSASAADL SSLTDVYQLE 1450 1460 1470 1480 1490 1500 LPKDQGGLGI AICEEDTING VMIESLTEHG GAAKDGRLKP GDHILAVDDE VVAGCPVEKF 1510 1520 1530 1540 1550 1560 ISLLKTAKAT VKLTVRAENP ACPAVPSSAV TVSGERKDNS QTPAVPAPDL EPIPSTSRSS 1570 1580 1590 1600 1610 1620 TPAVFASDPA TCPIIPGCET TIEISKGQTG LGLSIVGGSD TLLGAIIIHE VYEEGAACKD 1630 1640 1650 1660 1670 1680 GRLWAGDQIL EVNGIDLRKA THDEAINVLR QTPQRVRLTL YRDEAPYKEE DVCDTFTIEL 1690 1700 1710 1720 1730 1740 QKRPGKGLGL SIVGKRNDTG VFVSDIVKGG IADADGRLMQ GDQILMVNGE DVRHATQEAV 1750 1760 1770 1780 1790 1800 AALLKCSLGA VTLEVGRVKA APFHSERRPS QSSQVSESSL SSFTPPLSGI NTSESLESNS 1810 1820 1830 1840 1850 1860 KKNALASEIQ GLRTVEIKKG PADSLGLSIA GGVGSPLGDV PIFIAMMHPN GVAAQTQKLR 1870 1880 1890 1900 1910 1920 VGDRIVTICG TSTDGMTHTQ AVNLMKNASG SIEVQVVAGG DVSVVTGHQQ ELANPCLAFT 1930 1940 1950 1960 1970 1980 GLTSSSIFPD DLGPPQSKTI TLDRGPDGLG FSIVGGYGSP HGDLPIYVKT VFAKGAAAED 1990 2000 2010 2020 GRLKRGDQII AVNGQSLEGV THEEAVAILK RTKGTVTLMV LS
	Isoform 3 [UniParc]. Checksum: CAA3A0A924541F8D	FASTA	2,072	220,484
	10 20 30 40 50 60 MLETIDKNRA LQAAERLQSK LKERGDVANE DKLSLLKSVL QSPLFSQILN LQTSLQQLKD 70 80 90 100 110 120 QVNIATLATA AADHAHTPQF SSAVISNLQS ESLLLSPNHG NLEALPGPGA PAVMDGKPTC 130 140 150 160 170 180 DELDQLIKNM AQGRHVEIFE LLKPPCGGLG FSVVGLRSEN RGELGIFVQE IQEGSVAHRD 190 200 210 220 230 240 GRLKETDQIL AINGQVLDQT ITHQQAISIL QKAKDTVQLV IARGSLPPVS SPRISRSPSA 250 260 270 280 290 300 ASTISAHSNP MHWQHVETIE LVNDGSGLGF GIIGGKATGV IVKTILPGGV ADQHGRLCSG 310 320 330 340 350 360 DHILKIGDTD LAGMSSEQVA QVLRQCGNRV KLMIARGAVE ETPASSSLGI TLSSSTSSTS 370 380 390 400 410 420 EMRVDASTQK NDESETFDVE LTKNVQGLGI TIAGYIGDKK LEPSGIFVKS ITKSSAVEHD 430 440 450 460 470 480 GRIQIGDQII AVDGTNLQGF TNQQAVEVLR HTGQTVRLTL MRKGASQEAE LTSRGDTAKD 490 500 510 520 530 540 VDLPAENCEK DEESLSLKRN TSILPIEEEG FPLLSAELEE AEDVQQEAAL LTKWQRIMGI 550 560 570 580 590 600 NYEIVVAHVS KFSENSGLGI SLEATVGHHF IRSVLPEGPV GHSGKLFSGD ELLEVNGINL 610 620 630 640 650 660 LGENHQDVVN ILKELPIDVT MVCCRRTVPP IALSEMDSLD INDLELTEKP HIDLGEFIGS 670 680 690 700 710 720 SETEDPMLAM SDVDQNAEEI QTPLAMWEAG GQSIELEKGS RGLGFSILDY QDPIDPANTV 730 740 750 760 770 780 IVIRSLVPGG IAEKDGRLFP GDRLMFVNDI NLENSTLEEA VEALKGAPSG MVRIGVAKPL 790 800 810 820 830 840 PLSPEEGYVS AKEDAFLCSP HACKESGLSD KALFRADLAL IDTPDAESIA ESRFESQFSP 850 860 870 880 890 900 DNDSVYSTQA SIFSLHDGTC SDGMNYGPSL PSSPPKDVTS SSEVVLGLHL SLEELYTQNL 910 920 930 940 950 960 LQRQHAGSPP TDMRPAPTSG FPISDYTTTN AVEQKYECAN PVAWPHSQLP SSLSTSELAP 970 980 990 1000 1010 1020 ALPAVAQKYL TDQSSLASDA ESVNLQSMSQ EAFERTVTIA KGSSSLGMTV SANKDGLGVI 1030 1040 1050 1060 1070 1080 VRSIIHGGAI SRDGRIAVGD CILSINEEST ISLTNAQARA MLRRHSLIGP DIKITYVPAE 1090 1100 1110 1120 1130 1140 HLEEFRVSFG QQAGGIMALD IFSSYTGRDI PELPEREEGE GEESELQNAA YSSWSQPRRV 1150 1160 1170 1180 1190 1200 ELWREPSKSL GISIVGGRGM GSRLSNGEVM RGIFIKHVLE DSPAGKNGTL KPGDRIIEVD 1210 1220 1230 1240 1250 1260 GMDLRDASHE QAVEAIRKAG NPVVFMVQSI INRPRKSPLP SLPHSLYPKY SFSSTNPFAD 1270 1280 1290 1300 1310 1320 SLQLTTDQAP SQSESETEKP ALCNVPPSSP SVFSEMGSDC AQPSATAVSE DEDKEDEFGY 1330 1340 1350 1360 1370 1380 SWKNIQERYG SLTGQLHVIE LEKGQSGLGL SLAGNKDRTR MSVFIVGIDP TGAAGRDGRL 1390 1400 1410 1420 1430 1440 QIADELLEIN GQILYGRSHQ NASSIIKCAP SKVKIIFIRN ADAVNQMAVC PGIAADSPSS 1450 1460 1470 1480 1490 1500 TSDSPQNKEV EPCSTTSASA ADLSSLTDVY QLELPKDQGG LGIAICEEDT INGVMIESLT 1510 1520 1530 1540 1550 1560 EHGGAAKDGR LKPGDHILAV DDEVVAGCPV EKFISLLKTA KATVKLTVRA ENPACPAVPS 1570 1580 1590 1600 1610 1620 SAVTVSGERK DNSQTPAVPA PDLEPIPSTS RSSTPAVFAS DPATCPIIPG CETTIEISKG 1630 1640 1650 1660 1670 1680 QTGLGLSIVG GSDTLLGAII IHEVYEEGAA CKDGRLWAGD QILEVNGIDL RKATHDEAIN 1690 1700 1710 1720 1730 1740 VLRQTPQRVR LTLYRDEAPY KEEDVCDTFT IELQKRPGKG LGLSIVGKRN DTGVFVSDIV 1750 1760 1770 1780 1790 1800 KGGIADADGR LMQGDQILMV NGEDVRHATQ EAVAALLKCS LGAVTLEVGR VKAAPFHSER 1810 1820 1830 1840 1850 1860 RPSQSSQVSE SSLSSFTPPL SGINTSESLE SNSKKNALAS EIQGLRTVEI KKGPADSLGL 1870 1880 1890 1900 1910 1920 SIAGGVGSPL GDVPIFIAMM HPNGVAAQTQ KLRVGDRIVT ICGTSTDGMT HTQAVNLMKN 1930 1940 1950 1960 1970 1980 ASGSIEVQVV AGGDVSVVTG HQQELANPCL AFTGLTSSSI FPDDLGPPQS KTITLDRGPD 1990 2000 2010 2020 2030 2040 GLGFSIVGGY GSPHGDLPIY VKTVFAKGAA AEDGRLKRGD QIIAVNGQSL EGVTHEEAVA 2050 2060 2070 ILKRTKGTVT LMVSLEVTAR VEAAQPLAPL LL
	Isoform 4 [UniParc]. Checksum: 7861BBC636A9C862	FASTA	2,057	218,953
	10 20 30 40 50 60 MLETIDKNRA LQAAERLQSK LKERGDVANE DKLSLLKSVL QSPLFSQILN LQTSLQQLKD 70 80 90 100 110 120 QVNIATLATA AADHAHTPQF SSAVISNLQS ESLLLSPNHG NLEALPGPGA PAVMDGKPTC 130 140 150 160 170 180 DELDQLIKNM AQGRHVEIFE LLKPPCGGLG FSVVGLRSEN RGELGIFVQE IQEGSVAHRD 190 200 210 220 230 240 GRLKETDQIL AINGQVLDQT ITHQQAISIL QKAKDTVQLV IARGSLPPVS SPRISRSPSA 250 260 270 280 290 300 ASTISAHSNP MHWQHVETIE LVNDGSGLGF GIIGGKATGV IVKTILPGGV ADQHGRLCSG 310 320 330 340 350 360 DHILKIGDTD LAGMSSEQVA QVLRQCGNRV KLMIARGAVE ETPASSSLGI TLSSSTSSTS 370 380 390 400 410 420 EMRVDASTQK NDESETFDVE LTKNVQGLGI TIAGYIGDKK LEPSGIFVKS ITKSSAVEHD 430 440 450 460 470 480 GRIQIGDQII AVDGTNLQGF TNQQAVEVLR HTGQTVRLTL MRKGASQEAE LTSRGDTAKD 490 500 510 520 530 540 VDLPAENCEK DEESLSLKRN TSILPIEEEG FPLLSAELEE AEDVQQEAAL LTKWQRIMGI 550 560 570 580 590 600 NYEIVVAHVS KFSENSGLGI SLEATVGHHF IRSVLPEGPV GHSGKLFSGD ELLEVNGINL 610 620 630 640 650 660 LGENHQDVVN ILKELPIDVT MVCCRRTVPP IALSEMDSLD INDLELTEKP HIDLGEFIGS 670 680 690 700 710 720 SETEDPMLAM SDVDQNAEEI QTPLAMWEAG GQSIELEKGS RGLGFSILDY QDPIDPANTV 730 740 750 760 770 780 IVIRSLVPGG IAEKDGRLFP GDRLMFVNDI NLENSTLEEA VEALKGAPSG MVRIGVAKPL 790 800 810 820 830 840 PLSPEEGYVS AKEDAFLCSP HACKESGLSD KALFRADLAL IDTPDAESIA ESRFESQFSP 850 860 870 880 890 900 DNDSVYSTQA SIFSLHDGTC SDGMNYGPSL PSSPPKDVTS SSEVVLGLHL SLEELYTQNL 910 920 930 940 950 960 LQRQHAGSPP TDMRPAPTSG FPISDYTTTN AVEQKYECAN PVAWPHSQLP SSLSTSELAP 970 980 990 1000 1010 1020 ALPAVAQKYL TDQSSLASDA ESVNLQSMSQ EAFERTVTIA KGSSSLGMTV SANKDGLGVI 1030 1040 1050 1060 1070 1080 VRSIIHGGAI SRDGRIAVGD CILSINEEST ISLTNAQARA MLRRHSLIGP DIKITYVPAE 1090 1100 1110 1120 1130 1140 HLEEFRVSFG QQAGGIMALD IFSSYTGRDI PELPEREEGE GEESELQNAA YSSWSQPRRV 1150 1160 1170 1180 1190 1200 ELWREPSKSL GISIVGGRGM GSRLSNGEVM RGIFIKHVLE DSPAGKNGTL KPGDRIIEVD 1210 1220 1230 1240 1250 1260 GMDLRDASHE QAVEAIRKAG NPVVFMVQSI INRPRKSPLP SLPHSLYPKY SFSSTNPFAD 1270 1280 1290 1300 1310 1320 SLQLTTDQAP SQSESETEKP ALCNVPPSSP SVFSEMGSDC AQPSATAVSE DEDKEDEFGY 1330 1340 1350 1360 1370 1380 SWKNIQERYG SLTGQLHVIE LEKGQSGLGL SLAGNKDRTR MSVFIVGIDP TGAAGRDGRL 1390 1400 1410 1420 1430 1440 QIADELLEIN GQILYGRSHQ NASSIIKCAP SKVKIIFIRN ADAVNQMAVC PGIAADSPSS 1450 1460 1470 1480 1490 1500 TSDSPQNKEV EPCSTTSASA ADLSSLTDVY QLELPKDQGG LGIAICEEDT INGVMIESLT 1510 1520 1530 1540 1550 1560 EHGGAAKDGR LKPGDHILAV DDEVVAGCPV EKFISLLKTA KATVKLTVRA ENPACPAVPS 1570 1580 1590 1600 1610 1620 SAVTVSGERK DNSQTPAVPA PDLEPIPSTS RSSTPAVFAS DPATCPIIPG CETTIEISKG 1630 1640 1650 1660 1670 1680 QTGLGLSIVG GSDTLLGAII IHEVYEEGAA CKDGRLWAGD QILEVNGIDL RKATHDEAIN 1690 1700 1710 1720 1730 1740 VLRQTPQRVR LTLYRDEAPY KEEDVCDTFT IELQLQKRPG KGLGLSIVGK RNDTGVFVSD 1750 1760 1770 1780 1790 1800 IVKGGIADAD GRLMQGDQIL MVNGEDVRHA TQEAVAALLK CSLGAVTLEV GRVKAAPFHS 1810 1820 1830 1840 1850 1860 ERRPSQSSQV SESSLSSFTP PLSGINTSES LESNSKKNAL ASEIQGLRTV EIKKGPADSL 1870 1880 1890 1900 1910 1920 GLSIAGGVGS PLGDVPIFIA MMHPNGVAAQ TQKLRVGDRI VTICGTSTDG MTHTQAVNLM 1930 1940 1950 1960 1970 1980 KNASGSIEVQ VVAGGDVSVV TGHQQELANP CLAFTGLTSS SIFPDDLGPP QSKTITLDRG 1990 2000 2010 2020 2030 2040 PDGLGFSIVG GYGSPHGDLP IYVKTVFAKG AAAEDGRLKR GDQIIAVNGQ SLEGVTHEEA 2050 VAILKRTKGT VTLMVLS
	Isoform 5 [UniParc]. Checksum: 40BB9E94036D48CB	FASTA	87	9,845
	10 20 30 40 50 60 MLETIDKNRA LQAAERLQSK LKERGDVANE DKLSLLKSVL QSPLFSQILN LQTSLQQLKD 70 80 QVGWHHPQRP SRCSKDLVRK GSCFSTG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification, sequence, and mapping of mouse multiple PDZ domain protein gene, Mpdz." Simpson E.H., Suffolk R., Jackson I.J. Genomics 59:102-104(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). Strain: C57BL/6 X CBA. Tissue: Brain.
[2]	"Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene." Fehr C., Shirley R.L., Belknap J.K., Crabbe J.C., Buck K.J. J. Neurosci. 22:3730-3738(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANTS SER-541; VAL-691; ARG-801; ALA-859; ASN-880; SER-914; VAL-977; MET-1338; ASN-1433 AND ASN-1767. Strain: 129/J, A/HeJ, AKR/J, BALB/cJ, C3H/J, C57BL/6J, C57BR/cdJ, C57L/J, CBA/J, CE/J, DBA/2J, DBA1/J, PL/J, SJL/J, SWR/J, WSP1, WSP2, WSR1 and WSR2. Tissue: Brain.
[3]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1894-2055 (ISOFORM 3). Strain: C57BL/6J. Tissue: Spinal ganglion and Testis.
[4]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J.
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Strain: FVB/N. Tissue: Brain, Kidney and Mammary tumor.
[6]	"Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein." Lee S.S., Weiss R.S., Javier R.T. Proc. Natl. Acad. Sci. U.S.A. 94:6670-6675(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1532-2055 (ISOFORM 4). Tissue: Pancreas.
[7]	"The direct association of the multiple PDZ domain containing proteins (MUPP-1) with the human c-Kit C-terminus is regulated by tyrosine kinase activity." Mancini A., Koch A., Stefan M., Niemann H., Tamura T. FEBS Lett. 482:54-58(2000) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH KIT, TISSUE SPECIFICITY.
[8]	"The multi-PDZ domain protein MUPP1 is a cytoplasmic ligand for the membrane-spanning proteoglycan NG2." Barritt D.S., Pearn M.T., Zisch A.H., Lee S.S., Javier R.T., Pasquale E.B., Stallcup W.B. J. Cell. Biochem. 79:213-224(2000) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH NG2.
[9]	"Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins." Lee S.S., Glaunsinger B., Mantovani F., Banks L., Javier R.T. J. Virol. 74:9680-9693(2000) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH ADENOVIRUS TYPE 9 E4-ORF1 PROTEIN.
[10]	"Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule." Hamazaki Y., Itoh M., Sasaki H., Furuse M., Tsukita S. J. Biol. Chem. 277:455-461(2002) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH CLDN1 AND F11R, DOMAINS, SUBCELLULAR LOCATION.
[11]	"Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells." Poliak S., Matlis S., Ullmer C., Scherer S.S., Peles E. J. Cell Biol. 159:361-372(2002) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION.
[12]	"Expression of MUPP1 protein in mouse brain." Sitek B., Poschmann G., Schmidtke K., Ullmer C., Maskri L., Andriske M., Stichel C.C., Zhu X.-R., Luebbert H. Brain Res. 970:178-187(2003) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY.
[13]	"The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction." Coyne C.B., Voelker T., Pichla S.L., Bergelson J.M. J. Biol. Chem. 279:48079-48084(2004) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH CXADR, DOMAIN.
[14]	"Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure." van de Pavert S.A., Kantardzhieva A., Malysheva A., Meuleman J., Versteeg I., Levelt C., Klooster J., Geiger S., Seeliger M.W., Rashbass P., Le Bivic A., Wijnholds J. J. Cell Sci. 117:4169-4177(2004) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH CRB1; MPP5 AND MPP4, SUBCELLULAR LOCATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ131869 mRNA. Translation: CAA10523.1. AF326526 mRNA. Translation: AAL37372.1. AF326527 mRNA. Translation: AAL37373.1. AF326528 mRNA. Translation: AAL37374.1. AF326529 mRNA. Translation: AAL37375.1. AF326530 mRNA. Translation: AAL37376.1. AF326531 mRNA. Translation: AAL37377.2. AF326532 mRNA. Translation: AAL37378.1. AF326533 mRNA. Translation: AAL37379.1. AF326534 mRNA. Translation: AAL37380.1. AF326535 mRNA. Translation: AAL37381.1. AF326536 mRNA. Translation: AAL37382.1. AF326537 mRNA. Translation: AAL37383.1. AF326538 mRNA. Translation: AAL37384.1. AF326539 mRNA. Translation: AAL37385.1. AF326540 mRNA. Translation: AAL37386.1. AF326541 mRNA. Translation: AAL37387.1. AF326542 mRNA. Translation: AAL37388.1. AF326543 mRNA. Translation: AAL37389.1. AF326544 mRNA. Translation: AAL37390.1. AK031321 mRNA. Translation: BAC27346.1. Different initiation. AK051782 mRNA. Translation: BAC34766.1. Different initiation. CR352325, AL670939 Genomic DNA. Translation: CAI25220.1. AL670939, CR352325 Genomic DNA. Translation: CAI25921.1. BC061504 mRNA. Translation: AAH61504.1. BC145117 mRNA. Translation: AAI45118.1. AF000168 mRNA. Translation: AAB57835.1.
IPI	IPI00404052. IPI00457729. IPI00466594. IPI00474705. IPI00608031.
PIR	T30259.
RefSeq	NP_034950.2. NM_010820.2.
UniGene	Mm.153039.
3D structure databases
ProteinModelPortal	Q8VBX6.
SMR	Q8VBX6. Positions 11-63, 120-466, 571-625, 684-776, 1002-1064, 1078-1232, 1270-1557, 1610-2055.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-41165N.
MINT	MINT-146667.
PTM databases
PhosphoSite	Q8VBX6.
Proteomic databases
PaxDb	Q8VBX6.
PRIDE	Q8VBX6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000102830; ENSMUSP00000099894; ENSMUSG00000028402.
GeneID	17475.
KEGG	mmu:17475.
UCSC	uc008tjw.2. mouse. uc008tjx.1. mouse. uc008tjy.1. mouse.
Organism-specific databases
CTD	8777.
MGI	MGI:1343489. Mpdz.
Phylogenomic databases
eggNOG	NOG252837.
GeneTree	ENSGT00650000092901.
HOVERGEN	HBG080134.
KO	K06095.
OrthoDB	EOG44F688.
Gene expression databases
ArrayExpress	Q8VBX6.
Bgee	Q8VBX6.
CleanEx	MM_MPDZ.
Genevestigator	Q8VBX6.
GermOnline	ENSMUSG00000028402. Mus musculus.
Family and domain databases
InterPro	IPR004172. L27. IPR015132. L27_2. IPR001478. PDZ. [Graphical view]
Pfam	PF09045. L27_2. 1 hit. PF00595. PDZ. 13 hits. [Graphical view]
SMART	SM00569. L27. 1 hit. SM00228. PDZ. 13 hits. [Graphical view]
SUPFAM	SSF50156. PDZ. 13 hits.
PROSITE	PS51022. L27. 1 hit. PS50106. PDZ. 13 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	292120.
SOURCE	Search...

Entry information

Entry name

MPDZ_MOUSE

Accession

Primary (citable) accession number: Q8VBX6
Secondary accession number(s): B7ZNA1 , O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 21, 2005
Last sequence update:	June 21, 2005
Last modified:	May 1, 2013
This is version 97 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program