Reviewed, UniProtKB/Swiss-Prot Q8VBW5 (BBX_MOUSE)

Names and origin

Protein names

Recommended name:
    HMG box transcription factor BBX
Alternative name(s):
    Bobby sox homolog
    HMG box-containing protein 2

Gene names

Name:	Bbx
Synonyms:	Hbp2

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	907 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Transcription factor that is necessary for cell cycle progression from G1 to S phase. Ref.5
Subcellular location	Nucleus Probable.
Sequence similarities	Contains 1 HMG box DNA-binding domain.
Sequence caution	The sequence AAL68987.1 differs from that shown. Reason: Miscellaneous discrepancy. Contaminating sequence. Potential poly-A sequence.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing Polymorphism
Ligand	DNA-binding
PTM	Phosphoprotein
Technical term	3D-structure
Gene Ontology (GO)
Biological process	regulation of transcription Inferred from electronic annotation. Source: UniProtKB-KW transcription Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8VBW5-1)

Also known as: BbxA;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8VBW5-2)

The sequence of this isoform differs from the canonical sequence as follows:
     55-135: Missing.
     223-249: Missing.
     730-730: S → SKGPFQSQKKNLFHKIVSKYKHKKEKPNVPE

Isoform 3 (identifier: Q8VBW5-3)

The sequence of this isoform differs from the canonical sequence as follows:
     732-751: Missing.

Isoform 4 (identifier: Q8VBW5-4)

The sequence of this isoform differs from the canonical sequence as follows:
     733-750: SGDKWSHKQFFLDAIHPT → PFQSQKKNLFHKIVSKYK
     751-907: Missing.

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 907

907

HMG box transcription factor BBX

PRO_0000232886

Regions

DNA binding

80 – 148

69

HMG box

Compositional bias

41 – 50

10

Poly-Glu

Compositional bias

444 – 540

97

Lys-rich

Compositional bias

715 – 718

4

Poly-Lys

Amino acid modifications

Modified residue

159

1

Phosphoserine By similarity

Modified residue

161

1

Phosphothreonine By similarity

Modified residue

477

1

Phosphoserine By similarity

Modified residue

483

1

Phosphoserine By similarity

Modified residue

776

1

Phosphothreonine By similarity

Modified residue

789

1

Phosphoserine By similarity

Modified residue

811

1

Phosphoserine By similarity

Natural variations

Alternative sequence

55 – 135

81

Missing in isoform 2.

VSP_018007

Alternative sequence

223 – 249

27

Missing in isoform 2.

VSP_018008

Alternative sequence

730

1

S → SKGPFQSQKKNLFHKIVSKY KHKKEKPNVPE in isoform 2.

VSP_018009

Alternative sequence

732 – 751

20

Missing in isoform 3.

VSP_018010

Alternative sequence

733 – 750

18

SGDKW…AIHPT → PFQSQKKNLFHKIVSKYK in isoform 4.

VSP_018011

Alternative sequence

751 – 907

157

Missing in isoform 4.

VSP_018012

Natural variant

30

1

P → L in strain: C3H/He. Ref.4

Natural variant

281

1

Q → H in strain: C3H/He. Ref.4

Experimental info

Sequence conflict

269

1

L → F in AAL58872. Ref.1

Sequence conflict

269

1

L → F in AAL58873. Ref.1

Sequence conflict

269

1

L → F in BAB30768. Ref.2

Sequence conflict

450

1

K → R in BAC34285. Ref.2

Sequence conflict

455

1

N → T in AAL58872. Ref.1

Sequence conflict

455

1

N → T in AAL58873. Ref.1

Secondary structure

1

.

.

.

.

.

.

.

.

.

907

Helix Strand Turn

Details...

Helix

86 – 101

16

Beta strand

103 – 105

3

Helix

109 – 119

11

Helix

123 – 140

18

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (BbxA) [UniParc]. Last modified April 18, 2006. Version 2. Checksum: 53E113D4B3DE4DAC	FASTA	907	100,783
	10 20 30 40 50 60 MKGSNRNKDH STEGEGDGKR PKRKCLQWHP LLAKKLLDFS EEEEEDEEEE DIDKVQLLEA 70 80 90 100 110 120 DGLEQDVAET EDDESPEQRA RRPMNAFLLF CKRHRSLVRQ EHPRLDNRGA TKILADWWAV 130 140 150 160 170 180 LDPKEKQKYT DMAKEYKDAF MKANPGYRWC PTTNKPVKSP TPTVNPRKKL WAFPPDSSRD 190 200 210 220 230 240 LPTPKKAKTE VPQLNFGMAD PTQMGGLSML LLAGEHALGT PEASSGTCRP DISESPELRQ 250 260 270 280 290 300 KSPLFQFAEI SSRTSHPDAP SKQCQASALF QFAEISSSTS QLGGTEPVKR CGNSALFQLA 310 320 330 340 350 360 EMCLASEGVK MEDTKLIKSK ESDGGRIEEI EKGKEERGTE VEKTTETSFQ KEAEFGKSAK 370 380 390 400 410 420 GNVRESKDLR DIEQLQMDNV MAIKVEDPKE IRKEPEDDQK YSHFPDFSYS ASSKIIISGV 430 440 450 460 470 480 PSRKDHMCHP HGIMIIEDPT TLNKPEKIKK KKKKNKLDRH GNDKSTPKKT CKKRQSSESD 490 500 510 520 530 540 IESVMYTIEA VAKGDWGVDK LGETPRKKVR PSSSGKGGIL DAKPPKKKVK SKEKKVSKEK 550 560 570 580 590 600 CSDITKESRP PDFLSISASK SVPGEVPEGI KAEPLTPTED ALPPSLPGQA KPEDSDCHRK 610 620 630 640 650 660 TETCGSRKSE RSCKGALYKT LVSEGMLTSL RANVDRGKRS SGKGNSSDHE GCWSEESWTF 670 680 690 700 710 720 NQSGTSGSKK FKKKLREDSF LGSAKLDEEF EKKFNSLPQY SPITFDRKCV STPRKKKKTG 730 740 750 760 770 780 NMSSESTKTS KGSGDKWSHK QFFLDAIHPT EAIFSEDKST TEPAFKVKNA LSIPNTPEPT 790 800 810 820 830 840 TMQEPLVGSQ KRKARKTKIT HLVRTADGRV SPAGGTLDDK PKEQLQRSLP KVPGTYCGDN 850 860 870 880 890 900 CSHSTVEEPR SSTPDMPAVS AFFSLAALAE VAAMENVHRG QRSTPLTHDG QPKEMPQAPV LISCADQ
	Isoform 2. Checksum: 3685A4E65B4A64EF	FASTA	829	91,878
	10 20 30 40 50 60 MKGSNRNKDH STEGEGDGKR PKRKCLQWHP LLAKKLLDFS EEEEEDEEEE DIDKYKDAFM 70 80 90 100 110 120 KANPGYRWCP TTNKPVKSPT PTVNPRKKLW AFPPDSSRDL PTPKKAKTEV PQLNFGMADP 130 140 150 160 170 180 TQMGGLSMLL LAGEHALGTP EISSRTSHPD APSKQCQASA LFQFAEISSS TSQLGGTEPV 190 200 210 220 230 240 KRCGNSALFQ LAEMCLASEG VKMEDTKLIK SKESDGGRIE EIEKGKEERG TEVEKTTETS 250 260 270 280 290 300 FQKEAEFGKS AKGNVRESKD LRDIEQLQMD NVMAIKVEDP KEIRKEPEDD QKYSHFPDFS 310 320 330 340 350 360 YSASSKIIIS GVPSRKDHMC HPHGIMIIED PTTLNKPEKI KKKKKKNKLD RHGNDKSTPK 370 380 390 400 410 420 KTCKKRQSSE SDIESVMYTI EAVAKGDWGV DKLGETPRKK VRPSSSGKGG ILDAKPPKKK 430 440 450 460 470 480 VKSKEKKVSK EKCSDITKES RPPDFLSISA SKSVPGEVPE GIKAEPLTPT EDALPPSLPG 490 500 510 520 530 540 QAKPEDSDCH RKTETCGSRK SERSCKGALY KTLVSEGMLT SLRANVDRGK RSSGKGNSSD 550 560 570 580 590 600 HEGCWSEESW TFNQSGTSGS KKFKKKLRED SFLGSAKLDE EFEKKFNSLP QYSPITFDRK 610 620 630 640 650 660 CVSTPRKKKK TGNMSSESTK TSKGPFQSQK KNLFHKIVSK YKHKKEKPNV PEKGSGDKWS 670 680 690 700 710 720 HKQFFLDAIH PTEAIFSEDK STTEPAFKVK NALSIPNTPE PTTMQEPLVG SQKRKARKTK 730 740 750 760 770 780 ITHLVRTADG RVSPAGGTLD DKPKEQLQRS LPKVPGTYCG DNCSHSTVEE PRSSTPDMPA 790 800 810 820 VSAFFSLAAL AEVAAMENVH RGQRSTPLTH DGQPKEMPQA PVLISCADQ
	Isoform 3. Checksum: B1913D47BAE14B1C	FASTA	887	98,500
	10 20 30 40 50 60 MKGSNRNKDH STEGEGDGKR PKRKCLQWHP LLAKKLLDFS EEEEEDEEEE DIDKVQLLEA 70 80 90 100 110 120 DGLEQDVAET EDDESPEQRA RRPMNAFLLF CKRHRSLVRQ EHPRLDNRGA TKILADWWAV 130 140 150 160 170 180 LDPKEKQKYT DMAKEYKDAF MKANPGYRWC PTTNKPVKSP TPTVNPRKKL WAFPPDSSRD 190 200 210 220 230 240 LPTPKKAKTE VPQLNFGMAD PTQMGGLSML LLAGEHALGT PEASSGTCRP DISESPELRQ 250 260 270 280 290 300 KSPLFQFAEI SSRTSHPDAP SKQCQASALF QFAEISSSTS QLGGTEPVKR CGNSALFQLA 310 320 330 340 350 360 EMCLASEGVK MEDTKLIKSK ESDGGRIEEI EKGKEERGTE VEKTTETSFQ KEAEFGKSAK 370 380 390 400 410 420 GNVRESKDLR DIEQLQMDNV MAIKVEDPKE IRKEPEDDQK YSHFPDFSYS ASSKIIISGV 430 440 450 460 470 480 PSRKDHMCHP HGIMIIEDPT TLNKPEKIKK KKKKNKLDRH GNDKSTPKKT CKKRQSSESD 490 500 510 520 530 540 IESVMYTIEA VAKGDWGVDK LGETPRKKVR PSSSGKGGIL DAKPPKKKVK SKEKKVSKEK 550 560 570 580 590 600 CSDITKESRP PDFLSISASK SVPGEVPEGI KAEPLTPTED ALPPSLPGQA KPEDSDCHRK 610 620 630 640 650 660 TETCGSRKSE RSCKGALYKT LVSEGMLTSL RANVDRGKRS SGKGNSSDHE GCWSEESWTF 670 680 690 700 710 720 NQSGTSGSKK FKKKLREDSF LGSAKLDEEF EKKFNSLPQY SPITFDRKCV STPRKKKKTG 730 740 750 760 770 780 NMSSESTKTS KAIFSEDKST TEPAFKVKNA LSIPNTPEPT TMQEPLVGSQ KRKARKTKIT 790 800 810 820 830 840 HLVRTADGRV SPAGGTLDDK PKEQLQRSLP KVPGTYCGDN CSHSTVEEPR SSTPDMPAVS 850 860 870 880 AFFSLAALAE VAAMENVHRG QRSTPLTHDG QPKEMPQAPV LISCADQ
	Isoform 4. Checksum: 5035FF87DBAEAF10	FASTA	750	83,986
	10 20 30 40 50 60 MKGSNRNKDH STEGEGDGKR PKRKCLQWHP LLAKKLLDFS EEEEEDEEEE DIDKVQLLEA 70 80 90 100 110 120 DGLEQDVAET EDDESPEQRA RRPMNAFLLF CKRHRSLVRQ EHPRLDNRGA TKILADWWAV 130 140 150 160 170 180 LDPKEKQKYT DMAKEYKDAF MKANPGYRWC PTTNKPVKSP TPTVNPRKKL WAFPPDSSRD 190 200 210 220 230 240 LPTPKKAKTE VPQLNFGMAD PTQMGGLSML LLAGEHALGT PEASSGTCRP DISESPELRQ 250 260 270 280 290 300 KSPLFQFAEI SSRTSHPDAP SKQCQASALF QFAEISSSTS QLGGTEPVKR CGNSALFQLA 310 320 330 340 350 360 EMCLASEGVK MEDTKLIKSK ESDGGRIEEI EKGKEERGTE VEKTTETSFQ KEAEFGKSAK 370 380 390 400 410 420 GNVRESKDLR DIEQLQMDNV MAIKVEDPKE IRKEPEDDQK YSHFPDFSYS ASSKIIISGV 430 440 450 460 470 480 PSRKDHMCHP HGIMIIEDPT TLNKPEKIKK KKKKNKLDRH GNDKSTPKKT CKKRQSSESD 490 500 510 520 530 540 IESVMYTIEA VAKGDWGVDK LGETPRKKVR PSSSGKGGIL DAKPPKKKVK SKEKKVSKEK 550 560 570 580 590 600 CSDITKESRP PDFLSISASK SVPGEVPEGI KAEPLTPTED ALPPSLPGQA KPEDSDCHRK 610 620 630 640 650 660 TETCGSRKSE RSCKGALYKT LVSEGMLTSL RANVDRGKRS SGKGNSSDHE GCWSEESWTF 670 680 690 700 710 720 NQSGTSGSKK FKKKLREDSF LGSAKLDEEF EKKFNSLPQY SPITFDRKCV STPRKKKKTG 730 740 750 NMSSESTKTS KGPFQSQKKN LFHKIVSKYK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"BBX is expressed in developing CNS and in neuronal tumours." Lee C.-J., Chan W.-I., Appleby V.J., Orme A.T., Scotting P.J. Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[2]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4). Strain: C57BL/6J. Tissue: Embryo, Pancreas and Testis.
[3]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6.
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANTS LEU-30 AND HIS-281. Strain: C3H/He and NMRI. Tissue: Mammary gland, Mammary tumor and Mesenchymal stem cell.
[5]	"HBP2: a new mammalian protein that complements the fission yeast MBF transcription complex." Sanchez-Diaz A., Blanco M.A., Jones N., Moreno S. Curr. Genet. 40:110-118(2001) [PubMed: 11680820] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-454, FUNCTION. Strain: C57BL/6J. Tissue: Mammary gland.
[6]	"Solution structure of the HMG-box domain of murine bobby sox homolog." RIKEN structural genomics initiative (RSGI) Submitted (AUG-2005) to the PDB data bank Cited for: STRUCTURE BY NMR OF 80-148.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF454943 mRNA. Translation: AAL58872.1.
AF454944 mRNA. Translation: AAL58873.1.
AK017487 mRNA. Translation: BAB30768.1.
AK029532 mRNA. Translation: BAC26500.2.
AK029747 mRNA. Translation: BAC26596.1.
AK049516 mRNA. Translation: BAC33788.1.
AK050488 mRNA. Translation: BAC34285.1.
AK157813 mRNA. Translation: BAE34207.1.
CT571273, AC109627 Genomic DNA. Translation: CAX15928.1.
CT571273, AC109627 Genomic DNA. Translation: CAX15929.1.
CT571273, AC109627 Genomic DNA. Translation: CAX15930.1.
CT571273, AC109627 Genomic DNA. Translation: CAX15931.1.
BC057869 mRNA. Translation: AAH57869.1.
BC066821 mRNA. Translation: AAH66821.1.
AF276950 mRNA. Translation: AAL68986.1.
AF276951 mRNA. Translation: AAL68987.1. Sequence problems.
AF276952 mRNA. Translation: AAL68988.1. Different initiation.

IPI

IPI00625898.
IPI00626888.
IPI00757307.
IPI00757891.

RefSeq

NP_081720.2.

UniGene

Mm.28940

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1WZ6	NMR	-	A	80-148	[»]

ModBase

Search...

Protein-protein interaction databases

STRING

Q8VBW5.

PTM databases

PhosphoSite

Q8VBW5.

Proteomic databases

PRIDE

Q8VBW5.

Genome annotation databases

Ensembl

ENSMUST00000066037; ENSMUSP00000066384; ENSMUSG00000022641; Mus musculus. [Genome view]
ENSMUST00000089399; ENSMUSP00000086821; ENSMUSG00000022641; Mus musculus. [Genome view]
ENSMUST00000114488; ENSMUSP00000110132; ENSMUSG00000022641; Mus musculus. [Genome view]
ENSMUST00000114489; ENSMUSP00000110133; ENSMUSG00000022641; Mus musculus. [Genome view]

GeneID

70508.

KEGG

mmu:70508.

UCSC

uc007zkn.1. mouse.
uc007zkp.1. mouse.
uc007zkq.1. mouse.
uc007zkr.1. mouse.

Organism-specific databases

CTD

70508.

MGI

MGI:1917758. Bbx.

Phylogenomic databases

HOVERGEN

Q8VBW5.

InParanoid

Q8VBW5.

OMA

PQAPVLI.

PhylomeDB

Q8VBW5.

Gene expression databases

ArrayExpress

Q8VBW5.

Bgee

Q8VBW5.

CleanEx

MM_BBX.

Genevestigator

Q8VBW5.

GermOnline

ENSMUSG00000022641. Mus musculus.

Family and domain databases

InterPro

IPR000910. HMG_HMG1/HMG2.
IPR009071. HMG_superfamily.
IPR019102. TF_HMG_box_BBX_DUF2028.
[Graphical view]

Gene3D

G3DSA:1.10.30.10. HMG-box. 1 hit.

Pfam

PF09667. DUF2028. 1 hit.
PF00505. HMG_box. 1 hit.
[Graphical view]

SMART

SM00398. HMG. 1 hit.
[Graphical view]

PROSITE

PS50118. HMG_BOX_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Other Resources

NextBio

331763.

SOURCE

Search...

Entry information

Entry name

BBX_MOUSE

Accession

Primary (citable) accession number: Q8VBW5
Secondary accession number(s): B8JK46 , B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 18, 2006
Last sequence update:	April 18, 2006
Last modified:	January 19, 2010
This is version 58 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)