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Q8V3R4

- PAP1_SWPV1

UniProt

Q8V3R4 - PAP1_SWPV1

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Protein
Poly(A) polymerase catalytic subunit
Gene
PAPL, SPV030
Organism
Swinepox virus (strain Swine/Nebraska/17077-99/1999) (SWPV)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activityi

ATP + RNA(n) = diphosphate + RNA(n+1).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei192 – 1921 By similarity
Active sitei194 – 1941 By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. polynucleotide adenylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. mRNA processing Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

mRNA processing, Transcription

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Poly(A) polymerase catalytic subunit (EC:2.7.7.19)
Alternative name(s):
Poly(A) polymerase large subunit
Short name:
PAP-L
Gene namesi
Name:PAPL
Ordered Locus Names:SPV030
OrganismiSwinepox virus (strain Swine/Nebraska/17077-99/1999) (SWPV)
Taxonomic identifieri300880 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeSuipoxvirus
Virus hostiSus scrofa (Pig) [TaxID: 9823]
ProteomesiUP000000871: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 470470Poly(A) polymerase catalytic subunit
PRO_0000308940Add
BLAST

Interactioni

Subunit structurei

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ8V3R4.
SMRiQ8V3R4. Positions 8-468.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamiPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFiPIRSF015693. VAC-48L_nuct. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8V3R4-1 [UniParc]FASTAAdd to Basket

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MNRQIANILE NYLGRYPSLN EYHTLKSQYR NIQKVNIFNK DIFISLLRKN    50
KKKFFSDLVC TQSDIKHSVL SYFSKQENTY SIGKLYTIIE LQTILVTTYT 100
DVLGVLTTKG PDIFSSTIYY NISSIKKLAT DIVHAMMITT VSDKIMGRHN 150
VSSLVGNVNT LMEEYLRRHN KNCICYGSYS LHLLNPDVRY GDIDILQTNS 200
RTFLIDLAFL IKFITGYNVV LLKVPYLKNY MVLKDHNDNH IIDSFNIRQD 250
TMETIPKILI DNIYIVDPVL QLMSMLKMFS QIDRLEDIVK NPDKVIIRLA 300
TLLEYVRINY GIILNGDHGN MPMLSTFNHD QRIITVQTNM YNFPFKKCFI 350
YLDENTLSRD ILHLNADDAV DFENVSNSAY LIHNDTMYTY FSNTILLRSE 400
NEIHEISTRA ISAHILLYQI LTKGDIIQPL SDIINSLISI EKCTIYKVIQ 450
RDKKTGKHGI IDIEKDIITH 470
Length:470
Mass (Da):54,520
Last modified:March 1, 2002 - v1
Checksum:iA4E8243F7690846F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF410153 Genomic DNA. Translation: AAL69769.1.
RefSeqiNP_570190.1. NC_003389.1.

Genome annotation databases

GeneIDi932422.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF410153 Genomic DNA. Translation: AAL69769.1 .
RefSeqi NP_570190.1. NC_003389.1.

3D structure databases

ProteinModelPortali Q8V3R4.
SMRi Q8V3R4. Positions 8-468.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 932422.

Family and domain databases

InterProi IPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view ]
Pfami PF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiPAP1_SWPV1
AccessioniPrimary (citable) accession number: Q8V3R4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: March 1, 2002
Last modified: May 14, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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