Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q8V3R4 (PAP1_SWPV1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Poly(A) polymerase catalytic subunit

EC=2.7.7.19
Alternative name(s):
Poly(A) polymerase large subunit
Short name=PAP-L
Gene names
Name:PAPL
Ordered Locus Names:SPV030
OrganismSwinepox virus (strain Swine/Nebraska/17077-99/1999) (SWPV) [Reference proteome]
Taxonomic identifier300880 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeSuipoxvirus
Virus hostSus scrofa (Pig) [TaxID: 9823]

Protein attributes

Sequence length470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activity

ATP + RNA(n) = diphosphate + RNA(n+1).

Subunit structure

Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit By similarity.

Sequence similarities

Belongs to the poxviridae poly(A) polymerase catalytic subunit family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 470470Poly(A) polymerase catalytic subunit
PRO_0000308940

Sites

Active site1921 By similarity
Active site1941 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8V3R4 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: A4E8243F7690846F

FASTA47054,520
        10         20         30         40         50         60 
MNRQIANILE NYLGRYPSLN EYHTLKSQYR NIQKVNIFNK DIFISLLRKN KKKFFSDLVC 

        70         80         90        100        110        120 
TQSDIKHSVL SYFSKQENTY SIGKLYTIIE LQTILVTTYT DVLGVLTTKG PDIFSSTIYY 

       130        140        150        160        170        180 
NISSIKKLAT DIVHAMMITT VSDKIMGRHN VSSLVGNVNT LMEEYLRRHN KNCICYGSYS 

       190        200        210        220        230        240 
LHLLNPDVRY GDIDILQTNS RTFLIDLAFL IKFITGYNVV LLKVPYLKNY MVLKDHNDNH 

       250        260        270        280        290        300 
IIDSFNIRQD TMETIPKILI DNIYIVDPVL QLMSMLKMFS QIDRLEDIVK NPDKVIIRLA 

       310        320        330        340        350        360 
TLLEYVRINY GIILNGDHGN MPMLSTFNHD QRIITVQTNM YNFPFKKCFI YLDENTLSRD 

       370        380        390        400        410        420 
ILHLNADDAV DFENVSNSAY LIHNDTMYTY FSNTILLRSE NEIHEISTRA ISAHILLYQI 

       430        440        450        460        470 
LTKGDIIQPL SDIINSLISI EKCTIYKVIQ RDKKTGKHGI IDIEKDIITH 

« Hide

References

[1]"The genome of swinepox virus."
Afonso C.L., Tulman E.R., Lu Z., Zsak L., Osorio F.A., Balinsky C., Kutish G.F., Rock D.L.
J. Virol. 76:783-790(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF410153 Genomic DNA. Translation: AAL69769.1.
RefSeqNP_570190.1. NC_003389.1.

3D structure databases

ProteinModelPortalQ8V3R4.
SMRQ8V3R4. Positions 8-468.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID932422.

Family and domain databases

InterProIPR024231. Pox_polyA_pol_nucTrfase.
IPR004976. Poxvirus_polyA_pol_cat.
IPR024397. Poxvirus_polyA_pol_cat_C.
IPR024398. Poxvirus_polyA_pol_cat_N.
[Graphical view]
PfamPF03296. Pox_polyA_pol. 1 hit.
PF12629. Pox_polyA_pol_C. 1 hit.
PF12630. Pox_polyA_pol_N. 1 hit.
[Graphical view]
PIRSFPIRSF015693. VAC-48L_nuct. 1 hit.
ProtoNetSearch...

Entry information

Entry namePAP1_SWPV1
AccessionPrimary (citable) accession number: Q8V3R4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: March 1, 2002
Last modified: May 14, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families