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Q8UYL3

- Q8UYL3_9POXV

UniProt

Q8UYL3 - Q8UYL3_9POXV

Protein
Submitted name:

CrmE protein

Gene

crmE

Organism
Vaccinia virus
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. protein binding Source: IntAct

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CrmE proteinImported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:crmEImported
    ORF Names:List195Imported, m8259RImported, mO259RImported, W86/88-1-195Imported
    OrganismiVaccinia virusImported
    Taxonomic identifieri10245 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirus

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    TNFP013753EBI-7539950,EBI-359977From a different organism.

    Protein-protein interaction databases

    MINTiMINT-6740381.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2UWIX-ray2.00A/B22-153[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ8UYL3.

    Family & Domainsi

    Family and domain databases

    InterProiIPR001368. TNFR/NGFR_Cys_rich_reg.
    [Graphical view]
    PfamiPF00020. TNFR_c6. 1 hit.
    [Graphical view]
    SMARTiSM00208. TNFR. 3 hits.
    [Graphical view]
    PROSITEiPS00652. TNFR_NGFR_1. 2 hits.
    PS50050. TNFR_NGFR_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8UYL3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKVIIILGF LIINTNSLSM KCEQGVSYYN SQELKCCKLC KPGTYSDHRC    50
    DKYSDTICGH CPSDTFTSIY NRSPWCHSCR GPCGTNRVEV TPCTPTTNRI 100
    CHCDSNSYCL LKASDGNCVT CAPKTKCGRG YGKKGEDEMG NTICKKCRKG 150
    TYSDIVSDSD QCKPMTR 167
    Length:167
    Mass (Da):18,510
    Last modified:March 1, 2002 - v1
    Checksum:i3B4A0D4A27FB797D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY678275 Genomic DNA. Translation: AAW23648.1.
    AY678277 Genomic DNA. Translation: AAW23930.1.
    DQ121394 Genomic DNA. Translation: ABD52700.1.
    KF866253 Genomic DNA. Translation: AHB23632.1.
    AJ315962 Genomic DNA. Translation: CAC83048.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY678275 Genomic DNA. Translation: AAW23648.1 .
    AY678277 Genomic DNA. Translation: AAW23930.1 .
    DQ121394 Genomic DNA. Translation: ABD52700.1 .
    KF866253 Genomic DNA. Translation: AHB23632.1 .
    AJ315962 Genomic DNA. Translation: CAC83048.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2UWI X-ray 2.00 A/B 22-153 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-6740381.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei Q8UYL3.

    Family and domain databases

    InterProi IPR001368. TNFR/NGFR_Cys_rich_reg.
    [Graphical view ]
    Pfami PF00020. TNFR_c6. 1 hit.
    [Graphical view ]
    SMARTi SM00208. TNFR. 3 hits.
    [Graphical view ]
    PROSITEi PS00652. TNFR_NGFR_1. 2 hits.
    PS50050. TNFR_NGFR_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Vaccinia virus CrmE encodes a soluble and cell surface tumor necrosis factor receptor that contributes to virus virulence."
      Reading P.C., Khanna A., Smith G.L.
      Virology 292:285-298(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: USSRImported.
    2. "An attenuated LC16m8 smallpox vaccine: analysis of full-genome sequence and induction of immune protection."
      Morikawa S., Sakiyama T., Hasegawa H., Saijo M., Maeda A., Kurane I., Maeno G., Kimura J., Hirama C., Yoshida T., Asahi-Ozaki Y., Sata T., Kurata T., Kojima A.
      J. Virol. 79:11873-11891(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: LC16m8Imported and LC16mOImported.
    3. "Genomic sequence of a clonal isolate of the vaccinia virus Lister strain employed for smallpox vaccination in France and its comparison to other orthopoxviruses."
      Garcel A., Crance J.M., Drillien R., Garin D., Favier A.L.
      J. Gen. Virol. 88:1906-1916(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: ListerImported.
    4. "Structure of CrmE, a virus-encoded tumour necrosis factor receptor."
      Graham S.C., Bahar M.W., Abrescia N.G., Smith G.L., Stuart D.I., Grimes J.M.
      J. Mol. Biol. 372:660-671(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 22-153.
    5. "Genome Sequence of WAU86/88-1, a New Variant of Vaccinia Virus Lister Strain from Poland."
      Mavian C., Lopez-Bueno A., Alcami A.
      Genome Announc. 2:e01086-13(2014) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: WAU86/88-1Imported.

    Entry informationi

    Entry nameiQ8UYL3_9POXV
    AccessioniPrimary (citable) accession number: Q8UYL3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3