Q8UWA9 (Q8UWA9_ASPUN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Estrogen receptor EMBL BAB79437.1

Gene names

Name:

ER EMBL BAB79437.1

Organism

Aspidoscelis uniparens (Desert grassland whiptail lizard) (Cnemidophorus uniparens) EMBL BAB79437.1

Taxonomic identifier

37197 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Sauropsida › Sauria › Lepidosauria › Squamata › Scleroglossa › Scincomorpha › Teiioidea › Teiidae › Aspidoscelis

Protein attributes

Sequence length	581 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the nuclear hormone receptor family. RuleBase RU000377 Contains 1 nuclear receptor DNA-binding domain. SAAS SAAS000536

Ontologies

Keywords
Biological process	Transcription Transcription regulation RuleBase RU004334 SAAS SAAS000536
Cellular component	Nucleus RuleBase RU004334 SAAS SAAS000536
Domain	Zinc-finger RuleBase RU004334 SAAS SAAS000536
Ligand	DNA-binding RuleBase RU004334 SAAS SAAS000536 Metal-binding Zinc
Molecular function	Receptor RuleBase RU004334 EMBL BAB79437.1
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	estrogen receptor activity Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro steroid binding Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8UWA9 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: A99F6C644FCF0D58	FASTA	581	65,650
	10 20 30 40 50 60 MTMTLHTKTS GVALLHQIQG SELEPLNRPQ LKIPLERPIS EMYVDSNKTG VFNYPEGATY 70 80 90 100 110 120 DFSTAAPVYS SASLSYASTN ESFGSGNLGG LHSLNNVPPS PVVFLQTAPQ LSPFIHHHNQ 130 140 150 160 170 180 QVPYYLENEP SSSAMREAFP TAFYRPGSEN RHHGGRASNS EKGSLSMEST KETRYCAVCN 190 200 210 220 230 240 DYASGYHYGV WSCEGCKAFF KRSIQGHNDY MCPATNQCTI DKNRRKSCQA CRLRKCYEVG 250 260 270 280 290 300 MMKGGIRKDR RGGRMLKHKR QRDELDGRNA VAVTEARNTT LWPSPLMIKH SKKNSPALSL 310 320 330 340 350 360 TAEQMVSALL DAEPPIVYSE YDPSSPFSEA SVMTLLTNLA DRELVHMITW AKRVPGFVDL 370 380 390 400 410 420 ALHDQVHLLE CAWLEILMIG LIWRSLEHPG KLLFAPNLLL DRSQGMCVEG FVEIFDMLLA 430 440 450 460 470 480 TSSRFRMMNI QGEEFVCLKS IILLNSGIYT FLSSTLRSLE EKEHIHRVLD KITDTLTHLM 490 500 510 520 530 540 AKSGLSLQQQ HRRLAQLLLM LSHIRHMSNK GMEHLYNMKC KNVVPLYDLL LEMLDAHRLH 550 560 570 580 ERRTPTSEQA MNQLTNASTS VHSLPPCYVN KREEENEQEA V

References

[1]	"Molecular cloning and characterization of reptilian estrogen receptor cDNAs." Sumida K., Ooe N., Saito K., Kaneko H. Mol. Cell. Endocrinol. 183:33-39(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB055221 mRNA. Translation: BAB79437.1.
3D structure databases
ProteinModelPortal	Q8UWA9.
SMR	Q8UWA9. Positions 171-244, 291-540.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG108344.
Family and domain databases
Gene3D	1.10.565.10. 2 hits. 3.30.50.10. 1 hit.
InterPro	IPR008946. Nucl_hormone_rcpt_ligand-bd. IPR000536. Nucl_hrmn_rcpt_lig-bd_core. IPR024178. Oest_rcpt/oest-rel_rcp. IPR001292. Oestr_rcpt. IPR024736. Oestrogen-typ_rcpt_final_C_dom. IPR001723. Str_hrmn_rcpt. IPR001628. Znf_hrmn_rcpt. IPR013088. Znf_NHR/GATA. [Graphical view]
Pfam	PF12743. ESR1_C. 1 hit. PF00104. Hormone_recep. 1 hit. PF02159. Oest_recep. 1 hit. PF00105. zf-C4. 1 hit. [Graphical view]
PIRSF	PIRSF500101. ER-a. 1 hit. PIRSF002527. ER-like_NR. 1 hit.
PRINTS	PR00543. OESTROGENR. PR00398. STRDHORMONER. PR00047. STROIDFINGER.
SMART	SM00430. HOLI. 1 hit. SM00399. ZnF_C4. 1 hit. [Graphical view]
SUPFAM	SSF48508. Str_ncl_receptor. 1 hit.
PROSITE	PS00031. NUCLEAR_REC_DBD_1. 1 hit. PS51030. NUCLEAR_REC_DBD_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8UWA9_ASPUN

Accession

Primary (citable) accession number: Q8UWA9

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	May 29, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)