Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

T-box transcription factor TBX20

Gene

TBX20

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Acts as a transcriptional regulator involved in heart developmental processes.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi103 – 282T-boxPROSITE-ProRule annotationAdd BLAST180

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
T-box transcription factor TBX20
Short name:
T-box protein 20
Short name:
cTbx20
Gene namesi
Name:TBX20
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002626921 – 440T-box transcription factor TBX20Add BLAST440

Proteomic databases

PaxDbiQ8UW76
PRIDEiQ8UW76

Expressioni

Developmental stagei

Expression detected from stage 2 in the primitive streak. During subsequent stages of primitive streak formation (stages 2-4), expression seen in the extraembryonic mesoderm and lateral mesoderm, and weakly in the elongating primitive streak. Concomitant with the onset of node and streak regression (stage 5), the expression in the lateral mesoderm extends to the anterior limit of the mesodermal cell layer. After gastrulation, continuously expressed in the heart-forming region and also detected in other regions such as the allantois, optic vesicle, hindbrain and ventral neural tube.1 Publication

Gene expression databases

BgeeiENSGALG00000012151

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000019818

Structurei

3D structure databases

ProteinModelPortaliQ8UW76
SMRiQ8UW76
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3586 Eukaryota
ENOG410Y98J LUCA
GeneTreeiENSGT00760000118897
HOGENOMiHOG000286000
HOVERGENiHBG067710
InParanoidiQ8UW76
KOiK10185
OMAiTVMTPFV
OrthoDBiEOG091G0I8R
PhylomeDBiQ8UW76
TreeFamiTF106341

Family and domain databases

CDDicd00182 TBOX, 1 hit
Gene3Di2.60.40.820, 1 hit
InterProiView protein in InterPro
IPR008967 p53-like_TF_DNA-bd
IPR036960 T-box_sf
IPR001699 TF_T-box
IPR018186 TF_T-box_CS
PANTHERiPTHR11267 PTHR11267, 1 hit
PfamiView protein in Pfam
PF00907 T-box, 1 hit
PRINTSiPR00937 TBOX
SMARTiView protein in SMART
SM00425 TBOX, 1 hit
SUPFAMiSSF49417 SSF49417, 1 hit
PROSITEiView protein in PROSITE
PS01283 TBOX_1, 1 hit
PS01264 TBOX_2, 1 hit
PS50252 TBOX_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q8UW76-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEYTPPPKPQ LSSRANAFSI AALMSSGSSK DKEAAESTIK PLEQFVEKSS
60 70 80 90 100
CAQPLSDLSG LEPHGDFSGS PSALCTEPLI PTTPIIPSEE MAKISCSLET
110 120 130 140 150
KELWDKFHEL GTEMIITKSG RRMFPTIRVS FSGVDPEAKY IVLMDIVPVD
160 170 180 190 200
NKRYRYAYHR SSWLVAGKAD PPLPARLYVH PDSPFTGEQL MKQMVSFEKV
210 220 230 240 250
KLTNNELDQH GHIILNSMHK YQPRVHIIKK KDHTASLLNL KSEEFRTFIF
260 270 280 290 300
PETVFTAVTA YQNQLITKLK IDSNPFAKGF RDSSRLTDIE RESVESLIQK
310 320 330 340 350
HSYARSPIRT YGGEDDLGDD SQATQSRGSA FTTSDNLSLS SWVSSSTSFP
360 370 380 390 400
GFQHPQSLSA LGTSTASIAT PIPHPIQGSL PPYSRLGMPL TPSAIASSMQ
410 420 430 440
GTGPTFPSFH MPRYHHYFQQ GPYAAIQGLR HSSAVMTPFV
Length:440
Mass (Da):48,687
Last modified:March 1, 2002 - v1
Checksum:i3F8AF3E327C0930C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB070554 mRNA Translation: BAB83622.1
RefSeqiNP_989475.1, NM_204144.1
UniGeneiGga.4201

Genome annotation databases

EnsembliENSGALT00000064440; ENSGALP00000052363; ENSGALG00000032097
GeneIDi373943
KEGGigga:373943

Similar proteinsi

Entry informationi

Entry nameiTBX20_CHICK
AccessioniPrimary (citable) accession number: Q8UW76
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health