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Protein
Submitted name:

Putative deoxyribonucleoside kinase

Gene

tk2

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei153Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi77 – 85ATPUniRule annotation9
Nucleotide bindingi212 – 216ATPUniRule annotation5

GO - Molecular functioni

Keywordsi

Molecular functionKinaseImported, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.1.145 6725
SABIO-RKQ8UVZ9

Names & Taxonomyi

Protein namesi
Submitted name:
Putative deoxyribonucleoside kinaseImported
Gene namesi
Name:tk2Imported
ORF Names:XELAEV_18024842mgImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus
Proteomesi
  • UP000186698 Componenti: Chromosome 4s

Organism-specific databases

XenbaseiXB-GENE-983645 tk2

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini73 – 270dNKInterPro annotationAdd BLAST198

Phylogenomic databases

HOVERGENiHBG006216
KOiK00857

Family and domain databases

InterProiView protein in InterPro
IPR002624 DCK/DGK
IPR031314 DNK_dom
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01712 dNK, 1 hit
PIRSFiPIRSF000705 DNK, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

Q8UVZ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVLLAARTC IRLCCTEHKT GALARFNLGA NTALTVRRIA SALCGRCNIM
60 70 80 90 100
RRGILPSGST GNGLKSREKS TVICVEGNIA SGKTSCLDYF SNTPDLEVFK
110 120 130 140 150
EPVAKWRNVC GHNPLGLMYQ DPNKWGLTLQ TYVQLTMLDI HTKPSISPVK
160 170 180 190 200
MMERSIYSAK YIFVENLYQS GKMPAVDYAI LTEWFKWIVK NTDTSVDLIV
210 220 230 240 250
YLQTSPEICY QRLKKRCREE ESVIPLEYLC AIHNLYEDWL VKQTSFSVPA
260 270
PVLVIDGNKE LEELTQHYEE NRTSILSL
Length:278
Mass (Da):31,471
Last modified:March 1, 2002 - v1
Checksum:i8EF41EBCB0120D5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF250861 mRNA Translation: AAL55705.1
CM004473 Genomic DNA Translation: OCT82319.1
RefSeqiNP_001082184.1, NM_001088715.1
UniGeneiXl.2832

Genome annotation databases

GeneIDi398276
KEGGixla:398276

Similar proteinsi

Entry informationi

Entry nameiQ8UVZ9_XENLA
AccessioniPrimary (citable) accession number: Q8UVZ9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: May 23, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health