Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Lysosomal cofactor/neurotrophic factor prosaposin

Gene

psap

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Lysosomal cofactor/neurotrophic factor prosaposinImported
Gene namesi
Name:psapImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-020108-1. psap.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi61 ↔ 136UniRule annotation
Disulfide bondi64 ↔ 130UniRule annotation
Disulfide bondi92 ↔ 104UniRule annotation
Disulfide bondi189 ↔ 262UniRule annotation
Disulfide bondi192 ↔ 256UniRule annotation
Disulfide bondi221 ↔ 232UniRule annotation
Disulfide bondi312 ↔ 385UniRule annotation
Disulfide bondi315 ↔ 379UniRule annotation
Disulfide bondi343 ↔ 354UniRule annotation
Disulfide bondi405 ↔ 478UniRule annotation
Disulfide bondi408 ↔ 472UniRule annotation
Disulfide bondi436 ↔ 447UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Proteomic databases

PaxDbiQ8UVZ4.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000045068.

Structurei

3D structure databases

ProteinModelPortaliQ8UVZ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 56Saposin A-typeInterPro annotationAdd BLAST41
Domaini57 – 140Saposin B-typeInterPro annotationAdd BLAST84
Domaini185 – 266Saposin B-typeInterPro annotationAdd BLAST82
Domaini308 – 389Saposin B-typeInterPro annotationAdd BLAST82
Domaini401 – 482Saposin B-typeInterPro annotationAdd BLAST82
Domaini484 – 520Saposin A-typeInterPro annotationAdd BLAST37

Phylogenomic databases

eggNOGiKOG1340. Eukaryota.
ENOG410XSI5. LUCA.
HOVERGENiHBG002617.

Family and domain databases

Gene3Di1.10.225.10. 4 hits.
InterProiIPR003119. SAP_A.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR021165. Saposin_chordata.
IPR008139. SaposinB_dom.
[Graphical view]
PfamiPF02199. SapA. 2 hits.
PF05184. SapB_1. 3 hits.
PF03489. SapB_2. 4 hits.
[Graphical view]
PIRSFiPIRSF002431. Saposin. 1 hit.
PRINTSiPR01797. SAPOSIN.
SMARTiSM00162. SAPA. 2 hits.
SM00741. SapB. 4 hits.
[Graphical view]
SUPFAMiSSF47862. SSF47862. 4 hits.
PROSITEiPS51110. SAP_A. 2 hits.
PS50015. SAP_B. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8UVZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMLLTLLLVT TAVASPLLGT EQCARGPPYW CQNVKTASLC GAVQHCQQNV
60 70 80 90 100
WNKPQMKTVP CDLCKEVLVV VEQLLKDNVT ESELLGYLEK ACQLIPDEGL
110 120 130 140 150
ANQCKEIVDN YFPVVMGIIQ GELDDPGVVC GALGLCVSQQ AALAKAQLTS
160 170 180 190 200
NEIPQVDLNQ RVSPFLLNIP QLLYPEEKRE TPKQKGDVCQ DCVTFISDTQ
210 220 230 240 250
DEARVNSSFI NTLIAQVENQ CELLGPGMSD MCKEYISQYG PLVFQQLMSM
260 270 280 290 300
QPKDICARAG FCPTKQKSVP MEKLLPAKSI PAVKMFPAVK VEKPVATMPA
310 320 330 340 350
KNLVRVRDSP QCAICEYVMK EIENMIQDQT SEAEIVQAVE KVCNILPSTL
360 370 380 390 400
TAQCKDLIET YGQAIIDLLV QEADPKTVCS FLALCSGVSH VPVMDKQHFA
410 420 430 440 450
AGGFCDVCKM AVRYVDGILE QNATQSEIEE AVLKVCSFLP DAVKDECNQL
460 470 480 490 500
IEQYEPLLVQ LLLQTLDPDF VCMKLGACPE AVQRLLGLNQ CSWGPAYWCK
510 520
NVQTAARCNA LDHCRRHVWS
Length:520
Mass (Da):57,432
Last modified:March 1, 2002 - v1
Checksum:iF9E620F84BA41CB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF276996 mRNA. Translation: AAL54381.1.
UniGeneiDr.75922.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF276996 mRNA. Translation: AAL54381.1.
UniGeneiDr.75922.

3D structure databases

ProteinModelPortaliQ8UVZ4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000045068.

Proteomic databases

PaxDbiQ8UVZ4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-020108-1. psap.

Phylogenomic databases

eggNOGiKOG1340. Eukaryota.
ENOG410XSI5. LUCA.
HOVERGENiHBG002617.

Family and domain databases

Gene3Di1.10.225.10. 4 hits.
InterProiIPR003119. SAP_A.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR021165. Saposin_chordata.
IPR008139. SaposinB_dom.
[Graphical view]
PfamiPF02199. SapA. 2 hits.
PF05184. SapB_1. 3 hits.
PF03489. SapB_2. 4 hits.
[Graphical view]
PIRSFiPIRSF002431. Saposin. 1 hit.
PRINTSiPR01797. SAPOSIN.
SMARTiSM00162. SAPA. 2 hits.
SM00741. SapB. 4 hits.
[Graphical view]
SUPFAMiSSF47862. SSF47862. 4 hits.
PROSITEiPS51110. SAP_A. 2 hits.
PS50015. SAP_B. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8UVZ4_DANRE
AccessioniPrimary (citable) accession number: Q8UVZ4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: November 30, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.