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Protein
Submitted name:

Transcription factor AP2 alpha 1

Gene

tfap2a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cartilage development Source: ZFIN
  • ectodermal placode development Source: ZFIN
  • ectodermal placode formation Source: ZFIN
  • embryonic cranial skeleton morphogenesis Source: ZFIN
  • hindbrain development Source: ZFIN
  • iridophore differentiation Source: ZFIN
  • melanocyte differentiation Source: ZFIN
  • neural crest cell development Source: ZFIN
  • neural crest cell fate specification Source: ZFIN
  • neuron differentiation Source: ZFIN
  • olfactory placode development Source: ZFIN
  • otic placode formation Source: ZFIN
  • otic vesicle development Source: ZFIN
  • peripheral nervous system development Source: ZFIN
  • regulation of transcription, DNA-templated Source: ZFIN
  • retina development in camera-type eye Source: ZFIN
  • skeletal system development Source: ZFIN
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor AP2 alpha 1Imported
Gene namesi
Name:tfap2aImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-011212-6. tfap2a.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: ZFIN
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ8UVE6.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000076787.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini205 – 399195TF_AP-2InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG3811. Eukaryota.
ENOG410XR9E. LUCA.
HOGENOMiHOG000231737.
HOVERGENiHBG002455.
KOiK09176.

Family and domain databases

InterProiIPR004979. TF_AP2.
IPR008121. TF_AP2_alpha_N.
IPR013854. TF_AP2_C.
[Graphical view]
PANTHERiPTHR10812. PTHR10812. 1 hit.
PfamiPF03299. TF_AP-2. 1 hit.
[Graphical view]
PRINTSiPR01749. AP2ATNSCPFCT.
PR01748. AP2TNSCPFCT.

Sequencei

Sequence statusi: Complete.

Q8UVE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLWKLTDNIK YEDFEDRHDG TSNGTARLPQ LGSVGQSPYT SAPPLSHTPN
60 70 80 90 100
SDFQPPYFPP PYQPIYPQSQ DPYSHVNDPY SINSLHAQSQ PQHPGWPGQR
110 120 130 140 150
QSQESSLLHQ HRGLPHQLCR EYRREVLLPS GHGIDTGLTD SIPIHGIPHS
160 170 180 190 200
LEDVQQVEDQ GIHIPDQTVI KKGPVSISKN NSNISAIPIN KDGLVGGVVN
210 220 230 240 250
PNEVFCSVPG RLSLLSSTSK YKVTVAEVQR RLSPPECLNA SLLGGVLRRA
260 270 280 290 300
KSKNGGRSLR EKLDKIGLNL PAGRRKAANV TLLTSLVEGE AVHLARDFGY
310 320 330 340 350
VCETEFPAKA IAEYMNRQHS DPNEQVQRKN MLLATKQICK EFTDLLSQDR
360 370 380 390 400
SPLGNSRPQP ILEPGIQSCL THFSLISHGF GTPAVCAALT ALQNYLTEAI
410 420 430
KAMDKMYLNN NPNSHSETGS KAGDKDEKHR K
Length:431
Mass (Da):47,535
Last modified:March 1, 2002 - v1
Checksum:iAA09E90B2FDE69D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF457191 mRNA. Translation: AAL51098.1.
RefSeqiNP_789829.2. NM_176859.3.
UniGeneiDr.8506.

Genome annotation databases

GeneIDi140618.
KEGGidre:140618.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF457191 mRNA. Translation: AAL51098.1.
RefSeqiNP_789829.2. NM_176859.3.
UniGeneiDr.8506.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000076787.

Proteomic databases

PaxDbiQ8UVE6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi140618.
KEGGidre:140618.

Organism-specific databases

CTDi7020.
ZFINiZDB-GENE-011212-6. tfap2a.

Phylogenomic databases

eggNOGiKOG3811. Eukaryota.
ENOG410XR9E. LUCA.
HOGENOMiHOG000231737.
HOVERGENiHBG002455.
KOiK09176.

Miscellaneous databases

NextBioi20797029.

Family and domain databases

InterProiIPR004979. TF_AP2.
IPR008121. TF_AP2_alpha_N.
IPR013854. TF_AP2_C.
[Graphical view]
PANTHERiPTHR10812. PTHR10812. 1 hit.
PfamiPF03299. TF_AP-2. 1 hit.
[Graphical view]
PRINTSiPR01749. AP2ATNSCPFCT.
PR01748. AP2TNSCPFCT.
ProtoNetiSearch...

Publicationsi

  1. "AP2 alpha 1 is expressed in gastrula epidermis, neural plate border and neural crest cells during zebrafish somitogenesis."
    Fuerthauer M., Thisse C., Thisse B.
    Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8UVE6_DANRE
AccessioniPrimary (citable) accession number: Q8UVE6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: May 11, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.