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Protein
Submitted name:

Alpha A crystallin

Gene

cryaa

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of eye lens Source: ZFIN
  • unfolded protein binding Source: ZFIN

GO - Biological processi

  • eye development Source: ZFIN
  • lens development in camera-type eye Source: ZFIN
  • visual perception Source: ZFIN

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha A crystallinImported
Submitted name:
Cryaa proteinImported
Submitted name:
Crystallin, alpha AImported
Gene namesi
Name:cryaaImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 1

Organism-specific databases

ZFINiZDB-GENE-020508-1 cryaa

Expressioni

Gene expression databases

BgeeiENSDARG00000053502

Interactioni

GO - Molecular functioni

  • unfolded protein binding Source: ZFIN

Protein-protein interaction databases

STRINGi7955.ENSDARP00000070021

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3N3EX-ray1.75A/B61-166[»]
SMRiQ8UUZ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 164SHSPInterPro annotationAdd BLAST112

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3591 Eukaryota
ENOG410YERS LUCA
GeneTreeiENSGT00760000119238
HOGENOMiHOG000233954
HOVERGENiHBG054766
KOiK09541
OMAiGERQDDH
OrthoDBiEOG091G0USC
TreeFamiTF105049

Family and domain databases

Gene3Di2.60.40.7901 hit
InterProiView protein in InterPro
IPR002068 A-crystallin/Hsp20_dom
IPR001436 Alpha-crystallin/HSP
IPR012274 Alpha-crystallin_A
IPR003090 Alpha-crystallin_N
IPR031107 HSP20
IPR008978 HSP20-like_chaperone
PANTHERiPTHR11527 PTHR11527, 1 hit
PTHR11527:SF36 PTHR11527:SF36, 1 hit
PfamiView protein in Pfam
PF00525 Crystallin, 1 hit
PF00011 HSP20, 1 hit
PIRSFiPIRSF036514 Sm_HSP_B1, 1 hit
PRINTSiPR00299 ACRYSTALLIN
SUPFAMiSSF49764 SSF49764, 1 hit
PROSITEiView protein in PROSITE
PS01031 SHSP, 1 hit

Sequencei

Sequence statusi: Complete.

Q8UUZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIAIQHPWF RRTLGYPTRL FDQFFGEGLF DYDLFPFTTS TVSPYYRHSL
60 70 80 90 100
FRNILDSSNS GVSEVRSDRE KFTVYLDVKH FSPDELSVKV TDDYVEIQGK
110 120 130 140 150
HGERQDDHGY ISREFHRRYR LPSNVDQSAI TCTLSADGLL TLCGPKTSGI
160 170
DAGRGDRTIP VTREDKSNSG SSS
Length:173
Mass (Da):19,714
Last modified:March 1, 2002 - v1
Checksum:i301D743DB91BBC13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248514 Genomic DNA No translation available.
BC083177 mRNA Translation: AAH83177.1
BC164886 mRNA Translation: AAI64886.1
AY035778 mRNA Translation: AAK61363.1
RefSeqiNP_694482.1, NM_152950.2
UniGeneiDr.78315

Genome annotation databases

EnsembliENSDART00000075539; ENSDARP00000070021; ENSDARG00000053502
GeneIDi100000769
KEGGidre:100000769

Similar proteinsi

Entry informationi

Entry nameiQ8UUZ6_DANRE
AccessioniPrimary (citable) accession number: Q8UUZ6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: April 25, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported