Reviewed, UniProtKB/Swiss-Prot Q8UK38 (GLGA2_AGRT5)

Names and origin

Protein names

Recommended name:
    Glycogen synthase 2
    EC=2.4.1.21
Alternative name(s):
    Starch [bacterial glycogen] synthase 2

Gene names

Name:	glgA2
Ordered Locus Names:	Atu5285
ORF Names:	AGR_pAT_410

Encoded on

Plasmid AT

Organism

Agrobacterium tumefaciens (strain C58 / ATCC 33970) [Complete proteome] [HAMAP]

Taxonomic identifier

176299 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length	509 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 509	509	Glycogen synthase 2 HAMAP MF_00484		PRO_0000188585
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8UK38-1 [UniParc]. Last modified October 19, 2002. Version 2. Checksum: E2D12821F286FA53	FASTA	509	55,309
	10 20 30 40 50 60 MRILAVTAEM FPFVKTGGLA DATSALPQAL ERKGADVRTL LPLYRGLTPL VRGRKPVLVA 70 80 90 100 110 120 NILEQPVSVY YVVSDGHKLL LLEAASLFDR DGHPYGVKGE PFADNDLRFA VLSKVAAEIA 130 140 150 160 170 180 LGAIDGWQPD VVHVHDWHAA LTCVYLADST PSVASVLTLH NLAFQGQYPL ERAGMLGLPS 190 200 210 220 230 240 HLCTVDCLEY YDDMSFLKGG LTTASAVTTV SPTYAREILT PEMGMGMHGV LARRRGDLRG 250 260 270 280 290 300 IVNGVDHDVW NPATDPYILA NFTAATATRR SLNKYALLQA LGLAPTQGPV FGVVSRLTWQ 310 320 330 340 350 360 KGIDLLPHVV PLIIERKGRL IVHGEGDTAL EDSLQALAKR YPELVCAHIG YDERLAHMIQ 370 380 390 400 410 420 AGSDFIIQPS RFEPCGLTQL YALRYGALPI VSRTGGLAET IIDANDAAIE AGVATGFQFE 430 440 450 460 470 480 PANEDDLRAA LERAISAYND RELFRRLQTQ AMQANFSWDK SAAQYMALFE SLVGNSTRET 490 500 DAVADIRTET FAKIRADRRL AGTPGSPTG

References

[1]

"The genome of the natural genetic engineer Agrobacterium tumefaciens C58." Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J. , Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W. Science 294:2317-2323(2001) [PubMed: 11743193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58." Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C. , Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S. Science 294:2323-2328(2001) [PubMed: 11743194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE007872 Genomic DNA. Translation: AAK90661.1.
PIR	AH3194.
RefSeq	NP_396220.1.
3D structure databases
SMR	Q8UK38. Positions 1-473.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8UK38.
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Genome annotation databases
GeneID	1137058.
GenomeReviews	Gene locus Atu5285 in contig AE007872_GR.
KEGG	atc:AGR_pAT_410. atu:Atu5285.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0297.
HOGENOM	HBG596384.
OMA	SFAAWFP.
PhylomeDB	Q8UK38.
Enzyme and pathway databases
BioCyc	ATUM176299-1:ATU5285-MONOMER.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth. [Tree]
InterPro	IPR011835. GlgA. IPR001296. Glyco_trans_1. IPR013534. Starch_synth_cat_dom. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA2_AGRT5

Accession

Primary (citable) accession number: Q8UK38

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 19, 2002
Last sequence update:	October 19, 2002
Last modified:	February 9, 2010
This is version 42 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)