Q8UIV8 (DAPB_AGRT5) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 62.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Dihydrodipicolinate reductase Short name=DHPR EC=1.3.1.26 | ||||||
| Gene names |
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| Organism | Agrobacterium tumefaciens (strain C58 / ATCC 33970) | ||||||
| Taxonomic identifier | 176299 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium |
Protein attributes
| Sequence length | 275 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | (S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = (S)-2,3-dihydrodipicolinate + NAD(P)H. HAMAP MF_00102 |
| Pathway | Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4. HAMAP MF_00102 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00102. |
| Sequence similarities | Belongs to the dihydrodipicolinate reductase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Diaminopimelate biosynthesis Lysine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | diaminopimelate biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | NADPH binding Inferred from electronic annotation. Source: InterPro dihydrodipicolinate reductase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 275 | 275 | Dihydrodipicolinate reductase HAMAP MF_00102 | PRO_0000141405 | |||
Sequences
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References
| [1] | "The genome of the natural genetic engineer Agrobacterium tumefaciens C58." Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J. Nester E.W.Science 294:2317-2323(2001) [PubMed: 11743193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C58 / ATCC 33970. |
| [2] | "Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58." Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C. Slater S.Science 294:2323-2328(2001) [PubMed: 11743194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C58 / ATCC 33970. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE007869 Genomic DNA. Translation: AAK86003.2. |
| PIR | B97381. |
| RefSeq | NP_353218.2. NC_003062.2. |
3D structure databases | |
| ProteinModelPortal | Q8UIV8. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q8UIV8. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 1132221. |
| GenomeReviews | Gene locus Atu0183 in contig AE007869_GR. |
| KEGG | atu:Atu0183. |
| PATRIC | 20810046. VBIAgrTum91616_0174. |
Phylogenomic databases | |
| eggNOG | COG0289. |
| HOGENOM | HBG594002. |
| OMA | IEISHKS. |
| PhylomeDB | Q8UIV8. |
| ProtClustDB | PRK00048. |
Enzyme and pathway databases | |
| BioCyc | ATUM176299-1:ATU0183-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00102. DapB. [Tree] |
| InterPro | IPR022663. DapB_C. IPR000846. DapB_N. IPR022664. DapB_N_CS. IPR011770. Dihydrodipicolinate_Rdtase. IPR023940. Dihydrodipicolinate_Rdtase_bac. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| KO | K00215. |
| PANTHER | PTHR20836. DapB_bac/pln. 1 hit. |
| Pfam | PF05173. DapB_C. 1 hit. PF01113. DapB_N. 1 hit. [Graphical view] |
| PIRSF | PIRSF000161. DHPR. 1 hit. |
| TIGRFAMs | TIGR00036. DapB. 1 hit. |
| PROSITE | PS01298. DAPB. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DAPB_AGRT5 | ||||||||
| Accession | Primary (citable) accession number: Q8UIV8 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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