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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei346 – 3461Proton donorUniRule annotation
Active sitei377 – 3771UniRule annotation
Active sitei506 – 5061UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciAGRO:ATU0404-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Atu0404
ORF Names:AGR_C_711
OrganismiAgrobacterium tumefaciens (strain C58 / ATCC 33970)
Taxonomic identifieri176299 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex
ProteomesiUP000000813 Componenti: Chromosome circular

Subcellular locationi

  1. Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 541541Glucose-6-phosphate isomerasePRO_0000180581Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi176299.Atu0404.

Structurei

3D structure databases

ProteinModelPortaliQ8UI94.
SMRiQ8UI94. Positions 7-537.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8UI94-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQATIEKLKA TASSTAATDL RAAFAADDQR FSRFSVKFDD LLMDYSKCAV
60 70 80 90 100
NEEIVTLLEQ LAREGGVEAK REEMFSGKAI NFTEDRAVLH TALRNRSNTP
110 120 130 140 150
VLVDDKDVMP DVNGVLAAMG KFADAIRSGS LKGATGKKIT DVVNIGIGGS
160 170 180 190 200
DLGPVMATLA LAPFHDGPRA HFVSNIDGAH IADTLKLLDP ETSLFIIASK
210 220 230 240 250
TFTTIETMTN AATARRFIAE KLGEGAVKHH FAAVSTALDK VAAFGIESDR
260 270 280 290 300
IFGFWDWVGG RYSIWSAIGL PLMIAIGPDN FGKFLDGAHA MDRHFREAPI
310 320 330 340 350
RENLPMLLGL IGFYNRNVLD YPTRAILPYD QRLSRFPAYL QQLDMESNGK
360 370 380 390 400
GVTIDGTPVE GQSGPVVWGE PGTNGQHAFY QLIHQGTSVI PAEFMIAANG
410 420 430 440 450
FEPELRHQHQ LLIANCLAQS EALMKGRTLA EAKAQLTSKG MEDSQADFIA
460 470 480 490 500
PHRVFTGNRP SITFVYDKLT PFALGRLIAL YEHRVFVEGV LFRINSFDQW
510 520 530 540
GVELGKELAT GLLPVVEGKE SAAGHDSSTQ GLVKALAGLA G
Length:541
Mass (Da):58,709
Last modified:June 1, 2002 - v1
Checksum:i4077F32868CFA3D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007869 Genomic DNA. Translation: AAK86219.1.
PIRiAC2626.
B97408.
RefSeqiNP_353434.1. NC_003062.2.

Genome annotation databases

EnsemblBacteriaiAAK86219; AAK86219; Atu0404.
GeneIDi1132442.
KEGGiatu:Atu0404.
PATRICi20810493. VBIAgrTum91616_0395.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007869 Genomic DNA. Translation: AAK86219.1.
PIRiAC2626.
B97408.
RefSeqiNP_353434.1. NC_003062.2.

3D structure databases

ProteinModelPortaliQ8UI94.
SMRiQ8UI94. Positions 7-537.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi176299.Atu0404.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK86219; AAK86219; Atu0404.
GeneIDi1132442.
KEGGiatu:Atu0404.
PATRICi20810493. VBIAgrTum91616_0395.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciAGRO:ATU0404-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C58 / ATCC 33970.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C58 / ATCC 33970.

Entry informationi

Entry nameiG6PI_AGRT5
AccessioniPrimary (citable) accession number: Q8UI94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: June 1, 2002
Last modified: January 7, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.