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Q8UI94 (G6PI_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:Atu0404
ORF Names:AGR_C_711
OrganismAgrobacterium tumefaciens (strain C58 / ATCC 33970) [Reference proteome] [HAMAP]
Taxonomic identifier176299 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex

Protein attributes

Sequence length541 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 541541Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180581

Sites

Active site3461Proton donor By similarity
Active site3771 By similarity
Active site5061 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8UI94 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 4077F32868CFA3D1

FASTA54158,709
        10         20         30         40         50         60 
MQATIEKLKA TASSTAATDL RAAFAADDQR FSRFSVKFDD LLMDYSKCAV NEEIVTLLEQ 

        70         80         90        100        110        120 
LAREGGVEAK REEMFSGKAI NFTEDRAVLH TALRNRSNTP VLVDDKDVMP DVNGVLAAMG 

       130        140        150        160        170        180 
KFADAIRSGS LKGATGKKIT DVVNIGIGGS DLGPVMATLA LAPFHDGPRA HFVSNIDGAH 

       190        200        210        220        230        240 
IADTLKLLDP ETSLFIIASK TFTTIETMTN AATARRFIAE KLGEGAVKHH FAAVSTALDK 

       250        260        270        280        290        300 
VAAFGIESDR IFGFWDWVGG RYSIWSAIGL PLMIAIGPDN FGKFLDGAHA MDRHFREAPI 

       310        320        330        340        350        360 
RENLPMLLGL IGFYNRNVLD YPTRAILPYD QRLSRFPAYL QQLDMESNGK GVTIDGTPVE 

       370        380        390        400        410        420 
GQSGPVVWGE PGTNGQHAFY QLIHQGTSVI PAEFMIAANG FEPELRHQHQ LLIANCLAQS 

       430        440        450        460        470        480 
EALMKGRTLA EAKAQLTSKG MEDSQADFIA PHRVFTGNRP SITFVYDKLT PFALGRLIAL 

       490        500        510        520        530        540 
YEHRVFVEGV LFRINSFDQW GVELGKELAT GLLPVVEGKE SAAGHDSSTQ GLVKALAGLA 


G 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE007869 Genomic DNA. Translation: AAK86219.1.
PIRAC2626.
B97408.
RefSeqNP_353434.1. NC_003062.2.

3D structure databases

ProteinModelPortalQ8UI94.
SMRQ8UI94. Positions 7-537.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING176299.Atu0404.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK86219; AAK86219; Atu0404.
GeneID1132442.
KEGGatu:Atu0404.
PATRIC20810493. VBIAgrTum91616_0395.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMARAHYVSN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycAGRO:ATU0404-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_AGRT5
AccessionPrimary (citable) accession number: Q8UI94
Entry history
Integrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: June 1, 2002
Last modified: June 11, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways