Q8UHB2 (COXZ_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c oxidase assembly protein CtaG

Gene names

Name:	ctaG
Synonyms:	coxG
Ordered Locus Names:	Atu0770
ORF Names:	AGR_C_1406

Organism

Agrobacterium tumefaciens (strain C58 / ATCC 33970)

Taxonomic identifier

176299 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length	202 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I By similarity. HAMAP MF_00155
Subcellular location	Cell inner membrane; Single-pass type II membrane protein; Periplasmic side Potential HAMAP MF_00155.
Sequence similarities	Belongs to the COX11/CtaG family.
Sequence caution	The sequence AAK86579.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
Ligand	Copper
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	copper ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 202	202	Cytochrome c oxidase assembly protein CtaG HAMAP MF_00155		PRO_0000206031
Regions
	Topological domain	1 – 16	16	Cytoplasmic Potential
	Transmembrane	17 – 39	23	Helical; Signal-anchor for type II membrane protein; Potential
	Topological domain	40 – 202	163	Periplasmic Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8UHB2 [UniParc]. Last modified October 10, 2002. Version 2. Checksum: B66A2FCCFF39E79F	FASTA	202	22,262
	10 20 30 40 50 60 MEAETARAGS QRVSNRSILV LCLVFFCAMI GMAYAAVPLY SLFCRVTGYN GTTQRVEQYS 70 80 90 100 110 120 DVILDKTINV TFDANTSNGL NWDFRPVDKM VKPKIGETIK VTFKATNRSP VATTGTAVFN 130 140 150 160 170 180 VTPMEAGAYF NKVECFCFTE TTLQPGETLE MPVVFFVDPD IATARETKSV HTLTLSYTFY 190 200 PAKTEKPVAS LPVKTESGDS KL

References

[1]

"The genome of the natural genetic engineer Agrobacterium tumefaciens C58." Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J. , Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W. Science 294:2317-2323(2001) [PubMed: 11743193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C58 / ATCC 33970.

[2]

"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58." Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C. , Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S. Science 294:2323-2328(2001) [PubMed: 11743194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C58 / ATCC 33970.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE007869 Genomic DNA. Translation: AAK86579.1. Different initiation.
PIR	AD2671. B97453.
RefSeq	NP_353794.1. NC_003062.2.
3D structure databases
ProteinModelPortal	Q8UHB2.
SMR	Q8UHB2. Positions 56-186.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8UHB2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1132808.
GenomeReviews	Gene locus Atu0770 in contig AE007869_GR.
KEGG	atu:Atu0770.
PATRIC	20811253. VBIAgrTum91616_0770.
Phylogenomic databases
eggNOG	COG3175.
HOGENOM	HBG525908.
OMA	KLIFYRA.
PhylomeDB	Q8UHB2.
ProtClustDB	PRK05089.
Enzyme and pathway databases
BioCyc	ATUM176299-1:ATU0770-MONOMER.
Family and domain databases
HAMAP	MF_00155. CtaG. [Tree]
InterPro	IPR023471. CtaG/Cox11_dom. IPR007533. Cyt_c_oxidase_assmbl_CtaG. [Graphical view]
Gene3D	G3DSA:2.60.370.10. CtaG_Cox11. 1 hit.
KO	K02258.
PANTHER	PTHR21320. CtaG_Cox11. 1 hit.
Pfam	PF04442. CtaG_Cox11. 1 hit. [Graphical view]
PIRSF	PIRSF005413. COX11. 1 hit.
SUPFAM	SSF110111. CtaG_Cox11. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COXZ_AGRT5

Accession

Primary (citable) accession number: Q8UHB2

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 10, 2002
Last sequence update:	October 10, 2002
Last modified:	January 25, 2012
This is version 60 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program