Reviewed, UniProtKB/Swiss-Prot Q8UH73 (MQO_AGRT5)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	Atu0811
ORF Names:	AGR_C_1485

Organism

Agrobacterium tumefaciens (strain C58 / ATCC 33970) [Complete proteome] [HAMAP]

Taxonomic identifier

176299 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length	523 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 523	523	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000128703

Sequences

	Sequence		Length	Mass (Da)
	Q8UH73-1 [UniParc]. Last modified November 1, 2002. Version 2. Checksum: D7AC909B157925F3	FASTA	523	57,422
	10 20 30 40 50 60 MAAKKVDVLL IGGGIMSATL GVWLRELEPT WSMQMLERLD GVALESSNGW NNAGTGHSAL 70 80 90 100 110 120 AELNYTPEDD NGNIKITQAV NINESFQISR QFWAWQVRNG VLKNPRSFIN HTPHMSFVWG 130 140 150 160 170 180 DENVAYLEKR YQALKASPLF AGMEFSTDPE QIKKWVPLMM EGRDPSQKLG ATWSPLGTDM 190 200 210 220 230 240 EFGEITRQFV SHLQSDQNFD LQVNSEVSDI QRNADGSWRV TYTNTKTDAE QVVDAKFVFI 250 260 270 280 290 300 GAGGGALHLL QMSGVPEADD YAGFPVGGSF LINENPDVTM QHLAKAYGKA SVGSPPMSVP 310 320 330 340 350 360 HLDTRVLGGK RVILFGPFAT FSTKFLKEGS YFDLVSSVTT SNAWPMVRVG IDEYPLVEYL 370 380 390 400 410 420 AGQLMMSDDD RFAALKEYFP NAKQGEWRLW QAGQRVQIIK RDEEKGGVLR LGTEVVAAKD 430 440 450 460 470 480 GSIAGLLGAS PGASTAAPIM LSVLEKVFKD KVATPEWQAK LRQIVPSYGT KLNDDPEKVR 490 500 510 520 EEWAYTAEHL QLPTPPQIDL EALKGAGAAP AGAPVKKVPD IAL

References

[1]

"The genome of the natural genetic engineer Agrobacterium tumefaciens C58." Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J. , Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W. Science 294:2317-2323(2001) [PubMed: 11743193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58." Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C. , Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S. Science 294:2323-2328(2001) [PubMed: 11743194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE007869 Genomic DNA. Translation: AAK86620.2. Different initiation.
PIR	AD2676. C97458.
RefSeq	NP_353835.2.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1132849.
GenomeReviews	Gene locus Atu0811 in contig AE007869_GR.
KEGG	atc:AGR_C_1485. atu:Atu0811.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8UH73.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_AGRT5

Accession

Primary (citable) accession number: Q8UH73

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 2002
Last sequence update:	November 1, 2002
Last modified:	November 4, 2008
This is version 31 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)