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Q8UH56 (BETB_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Betaine aldehyde dehydrogenase
Short name=BADH
EC=1.2.1.8
Gene names
Name:betB
Ordered Locus Names:Atu0829
ORF Names:AGR_C_1515
OrganismAgrobacterium tumefaciens (strain C58 / ATCC 33970)
Taxonomic identifier176299 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length493 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP MF_00804

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP MF_00804

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processbetaine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 493493Betaine aldehyde dehydrogenase HAMAP MF_00804
PRO_0000056535

Regions

Nucleotide binding234 – 2396NAD By similarity

Sites

Active site2561 By similarity
Active site2901 By similarity

Secondary structure

1 .................................................................... 493
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q8UH56 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 7636ADEEB5327833

FASTA49352,204
        10         20         30         40         50         60 
MTIATPLKAQ PKASHFIDGD YVEDNTGTPF ESIFPATGEM IAKLHAATPA IVERAIASAK 

        70         80         90        100        110        120 
RAQKEWAAMS PMARGRILKR AADIMRERND ALSTLETLDT GKPIQETIVA DPTSGADAFE 

       130        140        150        160        170        180 
FFGGIAPSAL NGDYIPLGGD FAYTKRVPLG VCVGIGAWNY PQQIACWKAA PALVAGNAMV 

       190        200        210        220        230        240 
FKPSENTPLG ALKIAEILIE AGLPKGLFNV IQGDRDTGPL LVNHPDVAKV SLTGSVPTGR 

       250        260        270        280        290        300 
KVAAAAAGHL KHVTMELGGK SPMIVFDDAD IESAVGGAML GNFYSSGQVC SNGTRVFVQK 

       310        320        330        340        350        360 
KAKARFLENL KRRTEAMILG DPLDYATHLG PLVSKAQQEK VLSYIEKGKA EGATLITGGG 

       370        380        390        400        410        420 
IPNNVAGEGA YVQPTVFADV TDDMTIAREE IFGPVMCVLD FDDEDEVLAR ANATEFGLAG 

       430        440        450        460        470        480 
GVFTADLARA HRVVDGLEAG TLWINTYNLC PVEIPFGGSK QSGFGRENSA AALEHYSELK 

       490 
TVYVSTGKVD APY

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE007869 Genomic DNA. Translation: AAK86635.1.
PIRAE2678.
B97460.
RefSeqNP_353850.1. NC_003062.2.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3R31X-ray2.15A/B1-493[»]
ProteinModelPortalQ8UH56.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8UH56.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1132867.
GenomeReviewsGene locus Atu0829 in contig AE007869_GR.
KEGGatu:Atu0829.
PATRIC20811367. VBIAgrTum91616_0825.

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHBG752218.
OMAIMRERNR.
PhylomeDBQ8UH56.
ProtClustDBPRK13252.

Enzyme and pathway databases

BioCycATUM176299-1:ATU0829-MONOMER.

Family and domain databases

HAMAPMF_00804. BADH.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR011264. Betaine_Ald_DH.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK00130.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR01804. BADH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETB_AGRT5
AccessionPrimary (citable) accession number: Q8UH56
Secondary accession number(s): Q7D0K9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: June 1, 2002
Last modified: January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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