Q8UGK8 (RPOZ_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit omega
Short name=RNAP omega subunit
EC=2.7.7.6

Alternative name(s):
RNA polymerase omega subunit
Transcriptase subunit omega

Gene names

Name:	rpoZ
Synonyms:	rnpO
Ordered Locus Names:	Atu1029
ORF Names:	AGR_C_1894

Organism

Agrobacterium tumefaciens (strain C58 / ATCC 33970)

Taxonomic identifier

176299 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length	129 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits By similarity. HAMAP MF_00366
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_00366
Subunit structure	The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.
Sequence similarities	Belongs to the RNA polymerase subunit omega family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	RNA polymerase complex Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 129	129	DNA-directed RNA polymerase subunit omega HAMAP MF_00366		PRO_0000128910

Sequences

	Sequence		Length	Mass (Da)
	Q8UGK8 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 2587506D1CE5D157	FASTA	129	14,297
	10 20 30 40 50 60 MARVTVEDCI DKVDNRFELV LLASHRARQI SQGSSITVDR DNDKNPVVAL REIADETLSP 70 80 90 100 110 120 DDLKEDLIHS LQKHVEVDEP EPDPVTLAAS AADGEDDDQP ETVTFDQMSE EELLAGIEGL VPPEKNDDY

References

[1]

"The genome of the natural genetic engineer Agrobacterium tumefaciens C58." Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J. , Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W. Science 294:2317-2323(2001) [PubMed: 11743193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C58 / ATCC 33970.

[2]

"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58." Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C. , Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S. Science 294:2323-2328(2001) [PubMed: 11743194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C58 / ATCC 33970.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE007869 Genomic DNA. Translation: AAK86837.2.
PIR	AD2703. D97485.
RefSeq	NP_354052.2. NC_003062.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q8UGK8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1133067.
GenomeReviews	Gene locus Atu1029 in contig AE007869_GR.
KEGG	atu:Atu1029.
PATRIC	20811801. VBIAgrTum91616_1041.
Phylogenomic databases
eggNOG	COG1758.
HOGENOM	HBG742204.
OMA	KVDNRFE.
PhylomeDB	Q8UGK8.
ProtClustDB	PRK00392.
Enzyme and pathway databases
BioCyc	ATUM176299-1:ATU1029-MONOMER.
Family and domain databases
HAMAP	MF_00366. RNApol_bact_RpoZ. [Tree]
InterPro	IPR003716. DNA-dir_RNA_pol_omega. IPR006110. RNA_poly_omega/K/RPABC2. IPR012293. RNAP_RPB6_omega. [Graphical view]
Gene3D	G3DSA:3.90.940.10. RNAP_RPB6_omega. 1 hit.
KO	K03060.
Pfam	PF01192. RNA_pol_Rpb6. 1 hit. [Graphical view]
SUPFAM	SSF63562. RNA_pol_omega. 1 hit.
TIGRFAMs	TIGR00690. RpoZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPOZ_AGRT5

Accession

Primary (citable) accession number: Q8UGK8

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 10, 2002
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program