Q8UFI8 (ALLH_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative ureidoglycolate hydrolase
EC=3.5.3.19

Gene names

Ordered Locus Names:	Atu1409
ORF Names:	AGR_C_2603

Organism

Agrobacterium tumefaciens (strain C58 / ATCC 33970)

Taxonomic identifier

176299 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length	162 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP MF_00616
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP MF_00616
Subunit structure	Homodimer By similarity. HAMAP MF_00616
Sequence similarities	Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	allantoin catabolic process Inferred from electronic annotation. Source: InterPro purine base metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ureidoglycolate hydrolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 162	162	Putative ureidoglycolate hydrolase HAMAP MF_00616		PRO_0000120560

Sequences

	Sequence		Length	Mass (Da)
	Q8UFI8 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 9FEA308131284E0F	FASTA	162	17,318
	10 20 30 40 50 60 MKTVTARPLT AEAFAPYGSV ADISELENLV SLADAYEGTG EAKTPVLQLV QAKAMSGSPV 70 80 90 100 110 120 ISQMEIHPFS SQTFLPLDQS SSLIVVCEAG EDGMPDESTI KAFLASPSQI VTYRHGVMHH 130 140 150 160 RLTPLAPSGR FAMTMWQTGR GGDTVLYPLH TPVSVDISDI TP

References

[1]

"The genome of the natural genetic engineer Agrobacterium tumefaciens C58." Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J. , Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W. Science 294:2317-2323(2001) [PubMed: 11743193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C58 / ATCC 33970.

[2]

"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58." Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C. , Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S. Science 294:2323-2328(2001) [PubMed: 11743194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C58 / ATCC 33970.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE007869 Genomic DNA. Translation: AAK87201.1.
PIR	AI2749. H97530.
RefSeq	NP_354416.1. NC_003062.2.
3D structure databases
ProteinModelPortal	Q8UFI8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8UFI8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1133447.
GenomeReviews	Gene locus Atu1409 in contig AE007869_GR.
KEGG	atu:Atu1409.
PATRIC	20812595. VBIAgrTum91616_1432.
Phylogenomic databases
eggNOG	COG3194.
OMA	CEAGEDG.
PhylomeDB	Q8UFI8.
ProtClustDB	PRK13395.
Enzyme and pathway databases
BioCyc	ATUM176299-1:ATU1409-MONOMER.
Family and domain databases
HAMAP	MF_00616. Ureidogly_hydro. Divergent sequence. [Tree]
InterPro	IPR011051. Cupin_RmlC_type. IPR007247. Ureidogly_hydro. IPR024060. Ureidoglycolate_hydrolase_dom. [Graphical view]
Gene3D	G3DSA:2.60.120.480. G3DSA:2.60.120.480. 1 hit.
KO	K01483.
Pfam	PF04115. Ureidogly_hydro. 1 hit. [Graphical view]
PIRSF	PIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLH_AGRT5

Accession

Primary (citable) accession number: Q8UFI8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program