Q8UEZ0 (RPIA_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	Atu1613
ORF Names:	AGR_C_2972

Organism

Agrobacterium tumefaciens (strain C58 / ATCC 33970)

Taxonomic identifier

176299 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length	231 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.
Sequence caution	The sequence AAK87392.2 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 231	231	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_0000158379

Sequences

	Sequence		Length	Mass (Da)
	Q8UEZ0 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: A209E2E2905C2CED	FASTA	231	24,140
	10 20 30 40 50 60 MDARQMKIKA AEAALSHVQD GMRLGIGTGS TAEEFVRLLA EKVAAGLKVE GVPTSERTAR 70 80 90 100 110 120 LCVELGVPLK SLDELPELDL TIDGADEVDH VLRLVKGGGG ALLREKIVAA ASGRMIVIAD 130 140 150 160 170 180 QSKVVETLGA FPLPIEINPF GQVATRIAIE KLAARSGLSG ELTMRSSGDG AFMTDGGHLI 190 200 210 220 230 LDASFGRIPD AEALARELNT IPGVVEHGLF INLASLAIIA GPEGARMMQA V

References

[1]	"The genome of the natural genetic engineer Agrobacterium tumefaciens C58." Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J. , Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W. Science 294:2317-2323(2001) [PubMed: 11743193] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C58 / ATCC 33970.
[2]	"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58." Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C. , Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S. Science 294:2323-2328(2001) [PubMed: 11743194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C58 / ATCC 33970.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE007869 Genomic DNA. Translation: AAK87392.2. Different initiation.
PIR	AI2774. G97554.
RefSeq	NP_354607.2. NC_003062.2.
3D structure databases
ProteinModelPortal	Q8UEZ0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8UEZ0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1133651.
GenomeReviews	Gene locus Atu1613 in contig AE007869_GR.
KEGG	atu:Atu1613.
PATRIC	20813001. VBIAgrTum91616_1631.
Phylogenomic databases
eggNOG	COG0120.
HOGENOM	HBG515603.
OMA	NLSLYVD.
PhylomeDB	Q8UEZ0.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	ATUM176299-1:ATU1613-MONOMER.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. IPR014036. Tscrpt_reg_HTH_DeoR. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF00455. DeoR. 1 hit. PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_AGRT5

Accession

Primary (citable) accession number: Q8UEZ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 23, 2003
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program