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Q8UEQ7 (MOBA_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Molybdenum cofactor guanylyltransferase

Short name=MoCo guanylyltransferase
EC=2.7.7.77
Alternative name(s):
GTP:molybdopterin guanylyltransferase
Mo-MPT guanylyltransferase
Molybdopterin guanylyltransferase
Molybdopterin-guanine dinucleotide synthase
Short name=MGD synthase
Gene names
Name:mobA
Ordered Locus Names:Atu1698
ORF Names:AGR_C_3120
OrganismAgrobacterium tumefaciens (strain C58 / ATCC 33970) [Reference proteome] [HAMAP]
Taxonomic identifier176299 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex

Protein attributes

Sequence length218 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor By similarity. HAMAP-Rule MF_00316

Catalytic activity

GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor. HAMAP-Rule MF_00316

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00316

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00316

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00316.

Domain

The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein By similarity. HAMAP-Rule MF_00316

Sequence similarities

Belongs to the MobA family.

Ontologies

Keywords
   Biological processMolybdenum cofactor biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Magnesium
Metal-binding
Nucleotide-binding
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processMo-molybdopterin cofactor biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

molybdenum cofactor guanylyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 218218Molybdenum cofactor guanylyltransferase HAMAP-Rule MF_00316
PRO_0000134877

Regions

Nucleotide binding18 – 203GTP By similarity

Sites

Metal binding1131Magnesium By similarity
Binding site301GTP By similarity
Binding site581GTP By similarity
Binding site781GTP By similarity
Binding site1131GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8UEQ7 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: A95970D68BB09A94

FASTA21823,402
        10         20         30         40         50         60 
MIAPPRKIPG LVPPGLILAG GLSRRMGSNK AMVTLGDAPL LSHVIRRVTP QVSDVTINAA 

        70         80         90        100        110        120 
ITDKGSWAEG FGLPLLPDTL NGHAGPLAGV LAGMRHFRDR ETAGSHFLTA PADSPFFPND 

       130        140        150        160        170        180 
LVVRLCEHLS DDAIVIAASS GQLHPVFALW PVALADDLED WLKNDANRRI RAFLARHVTI 

       190        200        210 
GVAFPPLETA RGSLDPFFNI NTPDELALAR SQLETMET 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE007869 Genomic DNA. Translation: AAK87470.1.
PIRAD2785.
E97564.
RefSeqNP_354685.1. NC_003062.2.

3D structure databases

ProteinModelPortalQ8UEQ7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING176299.Atu1698.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK87470; AAK87470; Atu1698.
GeneID1133736.
KEGGatu:Atu1698.
PATRIC20813167. VBIAgrTum91616_1712.

Phylogenomic databases

eggNOGCOG0746.
HOGENOMHOG000280423.
KOK03752.
OMATWAASHR.
OrthoDBEOG61041R.
ProtClustDBPRK00317.

Enzyme and pathway databases

BioCycAGRO:ATU1698-MONOMER.

Family and domain databases

HAMAPMF_00316. MobA.
InterProIPR025877. MobA-like_NTP_Trfase_dom.
IPR013482. Molybde_CF_guanTrfase.
[Graphical view]
PfamPF12804. NTP_transf_3. 1 hit.
[Graphical view]
TIGRFAMsTIGR02665. molyb_mobA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMOBA_AGRT5
AccessionPrimary (citable) accession number: Q8UEQ7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: June 1, 2002
Last modified: April 16, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families