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Q8UEP4 (SYR_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Atu1711
ORF Names:AGR_C_3144
OrganismAgrobacterium tumefaciens (strain C58 / ATCC 33970) [Reference proteome] [HAMAP]
Taxonomic identifier176299 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex

Protein attributes

Sequence length585 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 585585Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151522

Regions

Motif131 – 14111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q8UEP4 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 2E22BF2F2460BB9E

FASTA58564,633
        10         20         30         40         50         60 
MNIFADFDTR IKNALETLDL VKENREKVDF SRITVESPRD LSHGDVATNA AMVLAKPLGT 

        70         80         90        100        110        120 
NPRALAELLV PALQADGDVD GVNVAGPGFI NLKVSVGYWQ RLLADMIGQG VDFGRSTVGA 

       130        140        150        160        170        180 
GQKINVEYVS ANPTGPMHVG HCRGAVVGDT LANLLAFAGY GVTKEYYIND AGSQIDVLAR 

       190        200        210        220        230        240 
SVFLRYREAL GEDIGSIPSG LYPGDYLVPV GQALADEYGI KLRAMPEEKW LPIVKDKAID 

       250        260        270        280        290        300 
AMMVMIREDL ALLNVRHDVF FSERTLHEGN GGPILSAIND LTFKGHVYKG TLPPPKGELP 

       310        320        330        340        350        360 
DDWEDREQTL FRSTEVGDDM DRALMKSDGS YTYFAADVAY FKNKFDRGFS EMIYVLGADH 

       370        380        390        400        410        420 
GGYVKRLEAV ARAVSEGKSK LTVLLCQLVK LFRDGEPVKM SKRSGDFVTL RDVVDEVGRD 

       430        440        450        460        470        480 
PVRFMMLYRK NSEPLDFDFA KVTEQSKDNP VFYVQYAHAR CKSIFRQAQE AFPGLAPSAE 

       490        500        510        520        530        540 
DMAASVALIS DINELQLVAK LAEYPRLIES AALSHEPHRL AFYLYDLAGS FHGHWNKGKD 

       550        560        570        580 
HQELRFINDK NRELSIARLG LVNAVANVLK SGLTLLGADA PDEMR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE007869 Genomic DNA. Translation: AAK87484.1.
PIRAI2786.
C97566.
RefSeqNP_354699.1. NC_003062.2.

3D structure databases

ProteinModelPortalQ8UEP4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING176299.Atu1711.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK87484; AAK87484; Atu1711.
GeneID1133749.
KEGGatu:Atu1711.
PATRIC20813195. VBIAgrTum91616_1726.

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycAGRO:ATU1711-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_AGRT5
AccessionPrimary (citable) accession number: Q8UEP4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: June 1, 2002
Last modified: April 16, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries