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Q8UEA1

- GLSA_AGRT5

UniProt

Q8UEA1 - GLSA_AGRT5

Protein

Glutaminase

Gene

glsA

Organism
Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei64 – 641SubstrateUniRule annotation
    Binding sitei114 – 1141SubstrateUniRule annotation
    Binding sitei160 – 1601SubstrateUniRule annotation
    Binding sitei167 – 1671SubstrateUniRule annotation
    Binding sitei191 – 1911SubstrateUniRule annotation
    Binding sitei243 – 2431SubstrateUniRule annotation
    Binding sitei261 – 2611Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciAGRO:ATU1859-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:glsAUniRule annotation
    Ordered Locus Names:Atu1859
    ORF Names:AGR_C_3412
    OrganismiAgrobacterium tumefaciens (strain C58 / ATCC 33970)
    Taxonomic identifieri176299 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex
    ProteomesiUP000000813: Chromosome circular

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 309309GlutaminasePRO_0000110586Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi176299.Atu1859.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8UEA1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2066.
    HOGENOMiHOG000216890.
    KOiK01425.
    OMAiQRARRIN.
    OrthoDBiEOG6N94BK.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8UEA1-1 [UniParc]FASTAAdd to Basket

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    MQDIQGIVDS IYDSMLPRLG EGKVADYIPE LAKVDPNQFG IAITTVDGTT    50
    YTAGNALVPF SIQSISKVFM LTLALGKAGE TVWNRVGREP SGSSFNSIVQ 100
    LEHEHGIPRN PFVNAGAIVV TDIVLSGHQP REAIGELLRF VRYLADDDTI 150
    SIDDTVAKSE QATGFRNFAL ANFMRSFGNL HHPVEHTLGV YFHQCALSMT 200
    CAQLSRAGLF LANRGRNPLS GHTVVSDRRA RRINALMLTC GHYDGSGDFA 250
    YHVGLPGKSG VGGGIMAVAP GNASIAVWSP GLNKVGNSAL GSQALELLAT 300
    KTGWSVFGA 309
    Length:309
    Mass (Da):32,926
    Last modified:June 1, 2002 - v1
    Checksum:i65229FEFE6CC1135
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE007869 Genomic DNA. Translation: AAK87626.1.
    PIRiA97584.
    AI2804.
    RefSeqiNP_354841.1. NC_003062.2.

    Genome annotation databases

    EnsemblBacteriaiAAK87626; AAK87626; Atu1859.
    GeneIDi1133897.
    KEGGiatu:Atu1859.
    PATRICi20813495. VBIAgrTum91616_1872.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE007869 Genomic DNA. Translation: AAK87626.1 .
    PIRi A97584.
    AI2804.
    RefSeqi NP_354841.1. NC_003062.2.

    3D structure databases

    ProteinModelPortali Q8UEA1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 176299.Atu1859.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK87626 ; AAK87626 ; Atu1859 .
    GeneIDi 1133897.
    KEGGi atu:Atu1859.
    PATRICi 20813495. VBIAgrTum91616_1872.

    Phylogenomic databases

    eggNOGi COG2066.
    HOGENOMi HOG000216890.
    KOi K01425.
    OMAi QRARRIN.
    OrthoDBi EOG6N94BK.

    Enzyme and pathway databases

    BioCyci AGRO:ATU1859-MONOMER.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C58 / ATCC 33970.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C58 / ATCC 33970.

    Entry informationi

    Entry nameiGLSA_AGRT5
    AccessioniPrimary (citable) accession number: Q8UEA1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 24, 2004
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3