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Q8UE16 (EFTU_AGRT5) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Elongation factor Tu
Short name=EF-Tu
Gene names
Name:tufA
Ordered Locus Names:Atu1948
ORF Names:AGR_C_3557
AND
Name:tufB
Ordered Locus Names:Atu1966
ORF Names:AGR_C_3583
OrganismAgrobacterium tumefaciens (strain C58 / ATCC 33970) [Reference proteome] [HAMAP]
Taxonomic identifier176299 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium › Agrobacterium tumefaciens complex ›

Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processGTP catabolic process

Inferred from electronic annotation. Source: GOC

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 391391Elongation factor Tu HAMAP-Rule MF_00118
PRO_0000091280

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding76 – 805GTP By similarity
Nucleotide binding131 – 1344GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8UE16 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 9118A52F0199D8FF

FASTA39142,626
        10         20         30         40         50         60 
MAKSKFERNK PHVNIGTIGH VDHGKTSLTA AITKYFGEFK AYDQIDAAPE EKARGITIST 

        70         80         90        100        110        120 
AHVEYETPAR HYAHVDCPGH ADYVKNMITG AAQMDGAILV CSAADGPMPQ TREHILLARQ 

       130        140        150        160        170        180 
VGVPAIVVFL NKVDQVDDAE LLELVELEVR ELLSSYDFPG DDIPIIKGSA LAALEDSDKK 

       190        200        210        220        230        240 
IGEDAIRELM AAVDAYIPTP ERPIDQPFLM PIEDVFSISG RGTVVTGRVE RGIVKVGEEV 

       250        260        270        280        290        300 
EIVGIRPTSK TTVTGVEMFR KLLDQGQAGD NIGALVRGVT RDGVERGQIL CKPGSVKPHK 

       310        320        330        340        350        360 
KFMAEAYILT KEEGGRHTPF FTNYRPQFYF RTTDVTGIVS LPEGTEMVMP GDNVTVEVEL 

       370        380        390 
IVPIAMEEKL RFAIREGGRT VGAGIVASIV E

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE007869 Genomic DNA. Translation: AAK87709.1.
AE007869 Genomic DNA. Translation: AAK87724.1.
PIRAB2816.
AC2818.
C97596.
D97594.
RefSeqNP_354924.1. NC_003062.2.
NP_354939.1. NC_003062.2.

3D structure databases

ProteinModelPortalQ8UE16.
SMRQ8UE16. Positions 2-390.
ModBaseSearch...

Protein-protein interaction databases

STRING176299.Atu1966.

Proteomic databases

PRIDEQ8UE16.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1133986.
1134004.
KEGGatu:Atu1948.
atu:Atu1966.
PATRIC20813671. VBIAgrTum91616_1960.

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMACEFVGYN.
ProtClustDBPRK12736.

Family and domain databases

HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
IPR009000. Transl_elong_init/rib_B-barrel.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50465. Elong_init_C. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF50447. Translat_factor. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_AGRT5
AccessionPrimary (citable) accession number: Q8UE16
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: June 1, 2002
Last modified: May 29, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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