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Q8UE16

- EFTU_AGRT5

UniProt

Q8UE16 - EFTU_AGRT5

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Protein
Elongation factor Tu
Gene
tufA, Atu1948, AGR_C_3557
tufB, Atu1966, AGR_C_3583
Organism
Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarity
Nucleotide bindingi76 – 805GTP By similarity
Nucleotide bindingi131 – 1344GTP By similarity

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Elongation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciAGRO:ATU1948-MONOMER.
    AGRO:ATU1966-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor Tu
    Short name:
    EF-Tu
    Gene namesi
    Name:tufA
    Ordered Locus Names:Atu1948
    ORF Names:AGR_C_3557
    AND
    Name:tufB
    Ordered Locus Names:Atu1966
    ORF Names:AGR_C_3583
    OrganismiAgrobacterium tumefaciens (strain C58 / ATCC 33970)
    Taxonomic identifieri176299 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex
    ProteomesiUP000000813: Chromosome circular

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 391391Elongation factor TuUniRule annotation
    PRO_0000091280Add
    BLAST

    Proteomic databases

    PRIDEiQ8UE16.

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Protein-protein interaction databases

    STRINGi176299.Atu1966.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8UE16.
    SMRiQ8UE16. Positions 2-390.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 201192tr-type G
    Add
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni19 – 268G1 By similarity
    Regioni55 – 595G2 By similarity
    Regioni76 – 794G3 By similarity
    Regioni131 – 1344G4 By similarity
    Regioni169 – 1713G5 By similarity

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiISAPAAC.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8UE16-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKSKFERNK PHVNIGTIGH VDHGKTSLTA AITKYFGEFK AYDQIDAAPE    50
    EKARGITIST AHVEYETPAR HYAHVDCPGH ADYVKNMITG AAQMDGAILV 100
    CSAADGPMPQ TREHILLARQ VGVPAIVVFL NKVDQVDDAE LLELVELEVR 150
    ELLSSYDFPG DDIPIIKGSA LAALEDSDKK IGEDAIRELM AAVDAYIPTP 200
    ERPIDQPFLM PIEDVFSISG RGTVVTGRVE RGIVKVGEEV EIVGIRPTSK 250
    TTVTGVEMFR KLLDQGQAGD NIGALVRGVT RDGVERGQIL CKPGSVKPHK 300
    KFMAEAYILT KEEGGRHTPF FTNYRPQFYF RTTDVTGIVS LPEGTEMVMP 350
    GDNVTVEVEL IVPIAMEEKL RFAIREGGRT VGAGIVASIV E 391
    Length:391
    Mass (Da):42,626
    Last modified:June 1, 2002 - v1
    Checksum:i9118A52F0199D8FF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE007869 Genomic DNA. Translation: AAK87709.1.
    AE007869 Genomic DNA. Translation: AAK87724.1.
    PIRiAB2816.
    AC2818.
    C97596.
    D97594.
    RefSeqiNP_354924.1. NC_003062.2.
    NP_354939.1. NC_003062.2.

    Genome annotation databases

    EnsemblBacteriaiAAK87709; AAK87709; Atu1948.
    AAK87724; AAK87724; Atu1966.
    GeneIDi1133986.
    1134004.
    KEGGiatu:Atu1948.
    atu:Atu1966.
    PATRICi20813671. VBIAgrTum91616_1960.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE007869 Genomic DNA. Translation: AAK87709.1 .
    AE007869 Genomic DNA. Translation: AAK87724.1 .
    PIRi AB2816.
    AC2818.
    C97596.
    D97594.
    RefSeqi NP_354924.1. NC_003062.2.
    NP_354939.1. NC_003062.2.

    3D structure databases

    ProteinModelPortali Q8UE16.
    SMRi Q8UE16. Positions 2-390.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 176299.Atu1966.

    Proteomic databases

    PRIDEi Q8UE16.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK87709 ; AAK87709 ; Atu1948 .
    AAK87724 ; AAK87724 ; Atu1966 .
    GeneIDi 1133986.
    1134004.
    KEGGi atu:Atu1948.
    atu:Atu1966.
    PATRICi 20813671. VBIAgrTum91616_1960.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi ISAPAAC.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci AGRO:ATU1948-MONOMER.
    AGRO:ATU1966-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C58 / ATCC 33970.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C58 / ATCC 33970.

    Entry informationi

    Entry nameiEFTU_AGRT5
    AccessioniPrimary (citable) accession number: Q8UE16
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 19, 2002
    Last sequence update: June 1, 2002
    Last modified: September 3, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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