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Reviewed, UniProtKB/Swiss-Prot Q8UBZ7 (TRMD_AGRT5)

Last modified February 9, 2010. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    tRNA (guanine-N(1)-)-methyltransferase
    EC=2.1.1.31
Alternative name(s):
    M1G-methyltransferase
    tRNA [GM37] methyltransferase
Gene names
Name: trmD
Ordered Locus Names: Atu2701
ORF Names: AGR_C_4898
OrganismAgrobacterium tumefaciens (strain C58 / ATCC 33970) [Complete proteome] [HAMAP]
Taxonomic identifier176299 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacterium

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Specifically methylates guanosine-37 in various tRNAs By similarity. HAMAP MF_00605

Catalytic activity

S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N(1)-methylguanine. HAMAP MF_00605

Subunit structure

Homodimer By similarity. HAMAP MF_00605

Subcellular location

Cytoplasm Potential HAMAP MF_00605.

Sequence similarities

Belongs to the RNA methyltransferase trmD family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtRNA modification

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionRNA binding

Inferred from electronic annotation. Source: InterPro

tRNA (guanine-N1-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 232232tRNA (guanine-N(1)-)-methyltransferase HAMAP MF_00605
PRO_0000060314

Regions

Region133 – 1386S-adenosyl-L-methionine binding By similarity

Sites

Binding site1131S-adenosyl-L-methionine; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8UBZ7-1 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 1E4DF99272DB33DA

FASTA23225,340
        10         20         30         40         50         60 
MTFKATVLTL YPEMFPGHLQ YSLAGKALER GQWSLDPIQI REFATDRHRS VDDTPAGGGA 

        70         80         90        100        110        120 
GMVLKPDVLA AAIDHVSKGD TRPRLLMSPR GKPLSQNRVR ELAAGDGAII VCGRFEGVDQ 

       130        140        150        160        170        180 
RVIEARGLEE VSIGDYILSG GEPAALTLLD AVVRILPGVM GNDLSGVHES FEGGLLEHPH 

       190        200        210        220        230 
YTRPQLWEGR DIPAILTSGN HAAIDKWRHE QALALTKERR PDLLEKTQAE TK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE007869 Genomic DNA. Translation: AAK88421.1.
PIRAD2908.
D97683.
RefSeqNP_355636.1.

3D structure databases

SMRQ8UBZ7. Positions 4-228.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8UBZ7.

Genome annotation databases

GeneID1134739.
GenomeReviewsGene locus Atu2701 in contig AE007869_GR.
KEGGatc:AGR_C_4898.
atu:Atu2701.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0336.
HOGENOMHBG285805.
OMAHRSVDDT.
PhylomeDBQ8UBZ7.

Enzyme and pathway databases

BioCycATUM176299-1:ATU2701-MONOMER.

Family and domain databases

HAMAPMF_00605. TrmD.
[Tree]
InterProIPR016009. tRNA_m1G_MeTrfase.
IPR002649. tRNA_m1G_MeTrfase_bac.
[Graphical view]
PfamPF01746. tRNA_m1G_MT. 1 hit.
[Graphical view]
PIRSFPIRSF000386. tRNA_mtase. 1 hit.
TIGRFAMsTIGR00088. trmD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRMD_AGRT5
AccessionPrimary (citable) accession number: Q8UBZ7
Entry history
Integrated into UniProtKB/Swiss-Prot: December 6, 2002
Last sequence update: June 1, 2002
Last modified: February 9, 2010
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents