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Protein

Biofilm growth-associated repressor

Gene

bigR

Organism
Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Represses an operon that comprises at least itself and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi54 – 77H-T-H motifPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Biofilm growth-associated repressor
Gene namesi
Name:bigR
Ordered Locus Names:Atu3466
ORF Names:AGR_L_2725
OrganismiAgrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Taxonomic identifieri176299 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex
Proteomesi

Pathology & Biotechi

Disruption phenotypei

Cells show altered biofilm formation; on glass surfaces and on tobacco root surfaces, it exhibits a greater biofilm mass than the wild-type.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003053351 – 117Biofilm growth-associated repressorAdd BLAST117

Interactioni

Protein-protein interaction databases

STRINGi176299.Atu3466

Structurei

3D structure databases

ProteinModelPortaliQ8UAA8
SMRiQ8UAA8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 114HTH arsR-typePROSITE-ProRule annotationAdd BLAST95

Phylogenomic databases

eggNOGiENOG41080HT Bacteria
COG0640 LUCA
HOGENOMiHOG000144506
OMAiGREVMYR

Family and domain databases

CDDicd00090 HTH_ARSR, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011991 ArsR-like_HTH
IPR001845 HTH_ArsR_DNA-bd_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PRINTSiPR00778 HTHARSR
SMARTiView protein in SMART
SM00418 HTH_ARSR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50987 HTH_ARSR_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8UAA8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTETPLEKP LDIGEIPLPA MEKRATEVAI LLKTLAHPAR LMLACTLAQG
60 70 80 90 100
EFSVGELEAK LDIRQPTLSQ QLGVLREAGI VDTRREAKQI FYRLAEDKAA
110
RLIEALYAIF CAPEENL
Length:117
Mass (Da):12,986
Last modified:October 2, 2007 - v3
Checksum:iA8B313FCA39C191C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007870 Genomic DNA Translation: AAK89928.1
PIRiAI2982
F98300
RefSeqiNP_357143.1, NC_003063.2
WP_010973063.1, NC_003063.2

Genome annotation databases

EnsemblBacteriaiAAK89928; AAK89928; Atu3466
GeneIDi1135340
KEGGiatu:Atu3466
PATRICifig|176299.10.peg.3305

Entry informationi

Entry nameiBIGR_AGRFC
AccessioniPrimary (citable) accession number: Q8UAA8
Secondary accession number(s): Q7CSJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: October 2, 2007
Last modified: March 28, 2018
This is version 86 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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