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Q8U4M1 (Q8U4M1_PYRFU) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Ordered Locus Names:PF0060 EMBL AAL80184.1
OrganismPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) [Reference proteome] [HAMAP] EMBL AAL80184.1
Taxonomic identifier186497 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site3491S-adenosyl-L-methionine; via amide nitrogen PDB 3NMU PDB 3NVK

Sequences

Sequence LengthMass (Da)Tools
Q8U4M1 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 898FA9AA195CD911

FASTA40246,788
        10         20         30         40         50         60 
MKAFISENVR GIYAFDENGN LIEKRYFTDK PEKVLDQLLK GEITKDLEEL LNSLKEKGYD 

        70         80         90        100        110        120 
EFVFEHPELS RRAKELGFSA TTEFPNIAGE RLRSNPEEFL GENWFEEYYK VGVALTRMRI 

       130        140        150        160        170        180 
QEQSGARDKM VIQAIEALDD VDKVINLLVA RLREWYSLHF PELDELLPKH PQYVAFVKTV 

       190        200        210        220        230        240 
GHRDNINEEV LRELGLSEEK IKKILEAKEK TMGAWMDQTD IEVVRQLAEE IDRLYQLRKK 

       250        260        270        280        290        300 
LEDYIDRAMD DVAPNLKALV GAKLAARLIS LAGGLRELAM MPSSTIQVLG AEKALFRHLR 

       310        320        330        340        350        360 
TGAKPPKHGV IYQYPAINRS PWWQRGKIAR ALAGKLAIAA RVDYFSGEYI AEELKKELEA 

       370        380        390        400 
RIREIKEKYP KPPKRKREER KGKKPWKKDK KKKKKKEKPR RR 

« Hide

References

« Hide 'large scale' references
[1]"Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences."
Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T.
Genetics 152:1299-1305(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.
[2]"Alternative conformations of the archaeal Nop56/58-fibrillarin complex imply flexibility in box C/D RNPs."
Oruganti S., Zhang Y., Li H., Robinson H., Terns M.P., Terns R.M., Yang W., Li H.
J. Mol. Biol. 371:1141-1150(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 1-366.
[3]"Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle."
Xue S., Wang R., Yang F., Terns R.M., Terns M.P., Zhang X., Maxwell E.S., Li H.
Mol. Cell 39:939-949(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.71 ANGSTROMS) OF 1-369 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE.
[4]"The structure of the box C/D enzyme reveals regulation of RNA methylation."
Lapinaite A., Simon B., Skjaerven L., Rakwalska-Bange M., Gabel F., Carlomagno T.
Nature 502:519-523(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR OF 4-369.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE009950 Genomic DNA. Translation: AAL80184.1.
RefSeqNP_577789.1. NC_003413.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2NNWX-ray2.70A/C1-366[»]
3NMUX-ray2.73A/B1-369[»]
3NVIX-ray2.71A/C1-369[»]
3NVKX-ray3.21A/F1-363[»]
3NVMX-ray3.41A1-369[»]
4BY9NMR-C/F/I/L4-369[»]
ProteinModelPortalQ8U4M1.
SMRQ8U4M1. Positions 4-366.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-60605N.
STRING186497.PF0060.

Proteomic databases

PRIDEQ8U4M1.

Protocols and materials databases

DNASU1467889.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL80184; AAL80184; PF0060.
GeneID1467889.
KEGGpfu:PF0060.

Phylogenomic databases

eggNOGCOG1498.
HOGENOMHOG000227188.
KOK14564.
OMAWMDETDI.

Family and domain databases

InterProIPR002687. Nop_dom.
IPR012976. NOSIC.
[Graphical view]
PfamPF01798. Nop. 1 hit.
PF08060. NOSIC. 1 hit.
[Graphical view]
SMARTSM00931. NOSIC. 1 hit.
[Graphical view]
PROSITEPS51358. NOP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ8U4M1.

Entry information

Entry nameQ8U4M1_PYRFU
AccessionPrimary (citable) accession number: Q8U4M1
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: June 11, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)