Q8U4M1 (Q8U4M1_PYRFU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
NOP5/NOP56 related protein EMBL AAL80184.1

Gene names

Ordered Locus Names:

PF0060

Organism

Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

Taxonomic identifier

186497 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	402 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	S-adenosyl-L-methionine PDB 3NMU
Technical term	3D-structure PDB 2NNW PDB 3NMU Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Binding site	349	1	S-adenosyl-L-methionine; via amide nitrogen PDB 3NMU

Sequences

	Sequence		Length	Mass (Da)
	Q8U4M1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 898FA9AA195CD911	FASTA	402	46,788
	10 20 30 40 50 60 MKAFISENVR GIYAFDENGN LIEKRYFTDK PEKVLDQLLK GEITKDLEEL LNSLKEKGYD 70 80 90 100 110 120 EFVFEHPELS RRAKELGFSA TTEFPNIAGE RLRSNPEEFL GENWFEEYYK VGVALTRMRI 130 140 150 160 170 180 QEQSGARDKM VIQAIEALDD VDKVINLLVA RLREWYSLHF PELDELLPKH PQYVAFVKTV 190 200 210 220 230 240 GHRDNINEEV LRELGLSEEK IKKILEAKEK TMGAWMDQTD IEVVRQLAEE IDRLYQLRKK 250 260 270 280 290 300 LEDYIDRAMD DVAPNLKALV GAKLAARLIS LAGGLRELAM MPSSTIQVLG AEKALFRHLR 310 320 330 340 350 360 TGAKPPKHGV IYQYPAINRS PWWQRGKIAR ALAGKLAIAA RVDYFSGEYI AEELKKELEA 370 380 390 400 RIREIKEKYP KPPKRKREER KGKKPWKKDK KKKKKKEKPR RR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Alternative conformations of the archaeal Nop56/58-fibrillarin complex imply flexibility in box C/D RNPs." Oruganti S., Zhang Y., Li H., Robinson H., Terns M.P., Terns R.M., Yang W., Li H. J. Mol. Biol. 371:1141-1150(2007) [PubMed: 17617422] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 1-366.
[2]	"Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences." Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T. Genetics 152:1299-1305(1999) [PubMed: 10430560] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.
[3]	"Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle." Xue S., Wang R., Yang F., Terns R.M., Terns M.P., Zhang X., Maxwell E.S., Li H. Mol. Cell 39:939-949(2010) [PubMed: 20864039] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.73 ANGSTROMS) OF 4-369 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE009950 Genomic DNA. Translation: AAL80184.1.

RefSeq

NP_577789.1. NC_003413.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2NNW	X-ray	2.70	A/C	1-366	[»]
3NMU	X-ray	2.73	A/B	4-369	[»]
3NVI	X-ray	2.71	A/C	1-369	[»]
3NVK	X-ray	3.21	A/F	1-363	[»]
3NVM	X-ray	3.41	A	1-369	[»]

ProteinModelPortal

Q8U4M1.

SMR

Q8U4M1. Positions 4-366.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBPYRT00000004376; EBPYRP00000004237; EBPYRG00000004376.

GeneID

1467889.

GenomeReviews

Gene locus PF0060 in contig AE009950_GR.

KEGG

pfu:PF0060.

NMPDR

fig|186497.1.peg.60.

Phylogenomic databases

GeneTree

EBGT00050000022777.

HOGENOM

HBG611715.

OMA

FLPASTI.

PhylomeDB

Q8U4M1.

ProtClustDB

PRK14552.

Family and domain databases

InterPro

IPR012976. NOSIC.
IPR002687. SnoRNA-bd_dom.
[Graphical view]

Pfam

PF01798. Nop. 1 hit.
PF08060. NOSIC. 1 hit.
[Graphical view]

SMART

SM00931. NOSIC. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q8U4M1_PYRFU

Accession

Primary (citable) accession number: Q8U4M1

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)