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Q8U4M1

- Q8U4M1_PYRFU

UniProt

Q8U4M1 - Q8U4M1_PYRFU

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Protein
Submitted name:

NOP5/NOP56 related protein

Gene

PF0060

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi348 – 3481Iron-sulfur(4Fe-4S-S-AdoMet)Imported
Metal bindingi349 – 3491Iron-sulfur(4Fe-4S-S-AdoMet); via amide nitrogenImported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

Metal-bindingImported

Names & Taxonomyi

Protein namesi
Submitted name:
NOP5/NOP56 related proteinImported
Gene namesi
Ordered Locus Names:PF0060Imported
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)Imported
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000001013: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiQ8U4M1.

Interactioni

Protein-protein interaction databases

DIPiDIP-60605N.
STRINGi186497.PF0060.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2NNWX-ray2.70A/C1-366[»]
3NMUX-ray2.73A/B1-369[»]
3NVIX-ray2.71A/C1-369[»]
3NVKX-ray3.21A/F1-363[»]
3NVMX-ray3.41A1-369[»]
4BY9NMR-C/F/I/L4-369[»]
ProteinModelPortaliQ8U4M1.
SMRiQ8U4M1. Positions 4-366.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8U4M1.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1498.
HOGENOMiHOG000227188.
KOiK14564.
OMAiWMDETDI.

Family and domain databases

InterProiIPR002687. Nop_dom.
IPR012976. NOSIC.
[Graphical view]
PfamiPF01798. Nop. 1 hit.
PF08060. NOSIC. 1 hit.
[Graphical view]
SMARTiSM00931. NOSIC. 1 hit.
[Graphical view]
PROSITEiPS51358. NOP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8U4M1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKAFISENVR GIYAFDENGN LIEKRYFTDK PEKVLDQLLK GEITKDLEEL
60 70 80 90 100
LNSLKEKGYD EFVFEHPELS RRAKELGFSA TTEFPNIAGE RLRSNPEEFL
110 120 130 140 150
GENWFEEYYK VGVALTRMRI QEQSGARDKM VIQAIEALDD VDKVINLLVA
160 170 180 190 200
RLREWYSLHF PELDELLPKH PQYVAFVKTV GHRDNINEEV LRELGLSEEK
210 220 230 240 250
IKKILEAKEK TMGAWMDQTD IEVVRQLAEE IDRLYQLRKK LEDYIDRAMD
260 270 280 290 300
DVAPNLKALV GAKLAARLIS LAGGLRELAM MPSSTIQVLG AEKALFRHLR
310 320 330 340 350
TGAKPPKHGV IYQYPAINRS PWWQRGKIAR ALAGKLAIAA RVDYFSGEYI
360 370 380 390 400
AEELKKELEA RIREIKEKYP KPPKRKREER KGKKPWKKDK KKKKKKEKPR

RR
Length:402
Mass (Da):46,788
Last modified:June 1, 2002 - v1
Checksum:i898FA9AA195CD911
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL80184.1.
RefSeqiNP_577789.1. NC_003413.1.

Genome annotation databases

EnsemblBacteriaiAAL80184; AAL80184; PF0060.
GeneIDi1467889.
KEGGipfu:PF0060.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL80184.1 .
RefSeqi NP_577789.1. NC_003413.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2NNW X-ray 2.70 A/C 1-366 [» ]
3NMU X-ray 2.73 A/B 1-369 [» ]
3NVI X-ray 2.71 A/C 1-369 [» ]
3NVK X-ray 3.21 A/F 1-363 [» ]
3NVM X-ray 3.41 A 1-369 [» ]
4BY9 NMR - C/F/I/L 4-369 [» ]
ProteinModelPortali Q8U4M1.
SMRi Q8U4M1. Positions 4-366.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-60605N.
STRINGi 186497.PF0060.

Proteomic databases

PRIDEi Q8U4M1.

Protocols and materials databases

DNASUi 1467889.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL80184 ; AAL80184 ; PF0060 .
GeneIDi 1467889.
KEGGi pfu:PF0060.

Phylogenomic databases

eggNOGi COG1498.
HOGENOMi HOG000227188.
KOi K14564.
OMAi WMDETDI.

Miscellaneous databases

EvolutionaryTracei Q8U4M1.

Family and domain databases

InterProi IPR002687. Nop_dom.
IPR012976. NOSIC.
[Graphical view ]
Pfami PF01798. Nop. 1 hit.
PF08060. NOSIC. 1 hit.
[Graphical view ]
SMARTi SM00931. NOSIC. 1 hit.
[Graphical view ]
PROSITEi PS51358. NOP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences."
    Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T.
    Genetics 152:1299-1305(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1Imported.
  2. "Alternative conformations of the archaeal Nop56/58-fibrillarin complex imply flexibility in box C/D RNPs."
    Oruganti S., Zhang Y., Li H., Robinson H., Terns M.P., Terns R.M., Yang W., Li H.
    J. Mol. Biol. 371:1141-1150(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 1-366.
  3. "Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle."
    Xue S., Wang R., Yang F., Terns R.M., Terns M.P., Zhang X., Maxwell E.S., Li H.
    Mol. Cell 39:939-949(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.71 ANGSTROMS) OF 1-369 IN COMPLEX WITH IRON-SULFUR(4FE-4S-S-ADOMET).
  4. "The structure of the box C/D enzyme reveals regulation of RNA methylation."
    Lapinaite A., Simon B., Skjaerven L., Rakwalska-Bange M., Gabel F., Carlomagno T.
    Nature 502:519-523(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 4-369.

Entry informationi

Entry nameiQ8U4M1_PYRFU
AccessioniPrimary (citable) accession number: Q8U4M1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3