Q8U4D2 (Q8U4D2_PYRFU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Oligosaccharyl transferase stt3 subunit related protein EMBL AAL80280.1

Gene names

Ordered Locus Names:

PF0156

Organism

Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

Taxonomic identifier

186497 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	967 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Calcium PDB 2ZAG PDB 2ZAI Metal-binding PDB 2ZAG PDB 2ZAI
Molecular function	Transferase EMBL AAL80280.1
Technical term	3D-structure PDB 2ZAG PDB 2ZAI Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	protein glycosylation Inferred from electronic annotation. Source: InterPro
Cellular component	membrane Inferred from electronic annotation. Source: InterPro
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW oligosaccharyl transferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	554	1	Calcium PDB 2ZAG PDB 2ZAI
	Metal binding	759	1	Calcium; via carbonyl oxygen PDB 2ZAG PDB 2ZAI
	Metal binding	793	1	Calcium; via carbonyl oxygen PDB 2ZAG PDB 2ZAI
	Metal binding	796	1	Calcium PDB 2ZAG PDB 2ZAI

Sequences

	Sequence		Length	Mass (Da)
	Q8U4D2 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 413F6559AF8699ED	FASTA	967	108,585
	10 20 30 40 50 60 MVKTQIKEKK KDEKVTIPLP GKIKTVLAFL VVLAFAAYGF YIRHLTAGKY FSDPDTFYHF 70 80 90 100 110 120 EIYKLVLKEG LPRYYPMADA PFGSLIGEPL GLYILPAIFY KIISIFGYNE LEAFLLWPPF 130 140 150 160 170 180 VGFLSVIGVY LLGRKVLNEW AGMWGAIILS VLTANFSRTF SGNARGDGPF MMLFTFSAVL 190 200 210 220 230 240 MLYYLTEENK NKKIIWGTLF VLLAGISTAA WNGSPFGLMV LLGFASFQTI ILFIFGKINE 250 260 270 280 290 300 LREFIKEYYP AYLGILAISY LLTIPGIGKI GGFVRFAFEV FLGLVFLAIV MLYGGKYLNY 310 320 330 340 350 360 SDKKHRFAVV AVIVIAGFAG AYIYVGPKLF TLMGGAYQST QVYETVQELA KTDWGDVKVY 370 380 390 400 410 420 YGVEKPNGIV FFLGLVGAMI VTARYLYKLF KDGRRPHEEL FAITFYVMSI YLLWTAARFL 430 440 450 460 470 480 FLASYAIALM SGVFAGYVLE TVEKMKESIP IKAALGGVIA IMLLLIPLTH GPLLAQSAKS 490 500 510 520 530 540 MRTTEIETSG WEDALKWLRE NTPEYSTATS WWDYGYWIES SLLGQRRASA DGGHARDRDH 550 560 570 580 590 600 ILALFLARDG NISEVDFESW ELNYFLVYLN DWAKFNAISY LGGAITRREY NGDESGRGAV 610 620 630 640 650 660 TTLLPLPRYG EKYVNLYAKV IVDVSNSSVK VTVGDRECDP LMVTFTPSGK TIKGTGTCSD 670 680 690 700 710 720 GNAFPYVLHL TPTIGVLAYY KVATANFIKL AFGVPASTIP GFSDKLFSNF EPVYESGNVI 730 740 750 760 770 780 VYRFTPFGIY KIEENINGTW KQVYNLTPGK HELKLYISAF GRDIENATLY IYAINNEKII 790 800 810 820 830 840 EKIKIAEISH MDYLNEYPIA VNVTLPNATS YRFVLVQKGP IGVLLDAPKV NGEIRSPTNI 850 860 870 880 890 900 LREGESGEIE LKVGVDKDYT ADLYLRATFI YLVRKSGKDN EDYDAAFEPQ MDVFFITKIG 910 920 930 940 950 960 ENIQLKEGEN TVKVRAELPE GVISSYKDEL QRKYGDKLII RGIRVEPVFI AEKEYLMLEV SASAPHH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structure-guided identification of a new catalytic motif of oligosaccharyltransferase." Igura M., Maita N., Kamishikiryo J., Yamada M., Obita T., Maenaka K., Kohda D. EMBO J. 27:234-243(2008) [PubMed: 18046457] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 471-967 IN COMPLEX WITH CALCIUM.
[2]	"Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences." Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T. Genetics 152:1299-1305(1999) [PubMed: 10430560] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE009950 Genomic DNA. Translation: AAL80280.1.

RefSeq

NP_577885.1. NC_003413.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2ZAG	X-ray	3.00	A/B/C/D	471-967	[»]
2ZAI	X-ray	2.70	A/B/C/D	471-967	[»]

ProteinModelPortal

Q8U4D2.

SMR

Q8U4D2. Positions 487-966.

ModBase

Search...

Protein family/group databases

CAZy

GT66. Glycosyltransferase Family 66.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBPYRT00000005029; EBPYRP00000004890; EBPYRG00000005028.

GeneID

1467988.

GenomeReviews

Gene locus PF0156 in contig AE009950_GR.

KEGG

pfu:PF0156.

NMPDR

fig|186497.1.peg.159.

Phylogenomic databases

GeneTree

EBGT00050000022885.

HOGENOM

HBG727102.

OMA

GYWIESS.

ProtClustDB

CLSK253212.

Family and domain databases

InterPro

IPR003674. Oligo_trans_STT3.
[Graphical view]

KO

K07151.

Pfam

PF02516. STT3. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q8U4D2_PYRFU

Accession

Primary (citable) accession number: Q8U4D2

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)