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Protein

Protein-export membrane protein SecF

Gene

secF

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in protein export.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Protein family/group databases

TCDBi3.A.5.7.2. the general secretory pathway (sec) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-export membrane protein SecFUniRule annotation
Gene namesi
Name:secFUniRule annotation
Ordered Locus Names:PF0173
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000001013 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4321HelicalUniRule annotationAdd
BLAST
Transmembranei144 – 16421HelicalUniRule annotationAdd
BLAST
Transmembranei169 – 18921HelicalUniRule annotationAdd
BLAST
Transmembranei194 – 21421HelicalUniRule annotationAdd
BLAST
Transmembranei236 – 25621HelicalUniRule annotationAdd
BLAST
Transmembranei265 – 28521HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 296296Protein-export membrane protein SecFPRO_0000412711Add
BLAST

Proteomic databases

PRIDEiQ8U4B5.

Interactioni

Subunit structurei

Part of the protein translocation apparatus. Forms a complex with SecD.UniRule annotation

Protein-protein interaction databases

STRINGi186497.PF0173.

Structurei

3D structure databases

ProteinModelPortaliQ8U4B5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SecD/SecF family. SecF subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiarCOG03054. Archaea.
COG0341. LUCA.
HOGENOMiHOG000227503.
KOiK03074.
OMAiSTGFTMS.

Family and domain databases

HAMAPiMF_01464_A. SecF_A. 1 hit.
InterProiIPR022813. SecD/SecF_arch_bac.
IPR024921. SecF_arc.
[Graphical view]
PfamiPF02355. SecD_SecF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8U4B5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEVDNVIKE KLKLLVEMDP KKMIIYPLIV FGIAIIIIIA NYVMTGSFVK
60 70 80 90 100
EGIELRGGSV ITLQGVNVSP DEIAKSIKEK TGIDVTVEKF SGVGGSGVRV
110 120 130 140 150
YVSAGDDVNL VREALKEMFP DVEPQTVVIG PTFGEIVREQ GIKAIVYAFI
160 170 180 190 200
GMAIVVFLFF RVPVPSMTVV FSAFSDMIIA IALMNIFGIE LSQATIAALL
210 220 230 240 250
MLIGYSVDSN ILLTTRLLRR KEFTVEEAYY SSLKTGFTMS TTTLGALASL
260 270 280 290
WIFSTAQVID DIASVLIFGL LADFMNTWIL NAGVLRLYIA KREGKE
Length:296
Mass (Da):32,397
Last modified:June 1, 2002 - v1
Checksum:iE085185740790F68
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL80297.1.

Genome annotation databases

EnsemblBacteriaiAAL80297; AAL80297; PF0173.
KEGGipfu:PF0173.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL80297.1.

3D structure databases

ProteinModelPortaliQ8U4B5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi186497.PF0173.

Protein family/group databases

TCDBi3.A.5.7.2. the general secretory pathway (sec) family.

Proteomic databases

PRIDEiQ8U4B5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL80297; AAL80297; PF0173.
KEGGipfu:PF0173.

Phylogenomic databases

eggNOGiarCOG03054. Archaea.
COG0341. LUCA.
HOGENOMiHOG000227503.
KOiK03074.
OMAiSTGFTMS.

Family and domain databases

HAMAPiMF_01464_A. SecF_A. 1 hit.
InterProiIPR022813. SecD/SecF_arch_bac.
IPR024921. SecF_arc.
[Graphical view]
PfamiPF02355. SecD_SecF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSECF_PYRFU
AccessioniPrimary (citable) accession number: Q8U4B5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: June 1, 2002
Last modified: November 11, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.