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Protein

V-type ATP synthase subunit F

Gene

atpF

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ATP synthesis, Hydrogen ion transport, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type ATP synthase subunit FUniRule annotation
Alternative name(s):
V-ATPase subunit FUniRule annotation
Gene namesi
Name:atpFUniRule annotation
Ordered Locus Names:PF0181
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000001013 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 103103V-type ATP synthase subunit FPRO_0000144822Add
BLAST

Proteomic databases

PRIDEiQ8U4A7.

Interactioni

Protein-protein interaction databases

STRINGi186497.PF0181.

Structurei

Secondary structure

1
103
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi2 – 76Combined sources
Helixi9 – 1810Combined sources
Beta strandi21 – 255Combined sources
Helixi30 – 4415Combined sources
Beta strandi49 – 557Combined sources
Helixi56 – 627Combined sources
Beta strandi69 – 768Combined sources
Helixi89 – 968Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2QAIX-ray2.40A/B1-103[»]
ProteinModelPortaliQ8U4A7.
SMRiQ8U4A7. Positions 1-97.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8U4A7.

Family & Domainsi

Sequence similaritiesi

Belongs to the V-ATPase F subunit family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04102. Archaea.
COG1436. LUCA.
HOGENOMiHOG000056544.
KOiK02122.
OMAiQIPDKFG.

Family and domain databases

Gene3Di3.40.50.10580. 1 hit.
HAMAPiMF_00312. ATP_synth_F_arch.
InterProiIPR008218. ATPase_V1-cplx_f_g_su.
IPR022944. ATPase_V1-cplx_fsu_bac/arc.
IPR005772. ATPase_V1-cplx_fsu_euk.
[Graphical view]
PANTHERiPTHR13861. PTHR13861. 1 hit.
PfamiPF01990. ATP-synt_F. 1 hit.
[Graphical view]
SUPFAMiSSF159468. SSF159468. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8U4A7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIVVMGDSD TVVGFRLAGV HEAYEYDESL ESVERARNKL RELLERDDVG
60 70 80 90 100
IILITERLAQ RIGSLPEVKF PIILQIPDKF GSIYGEDILR DVVRRAIGVE

LKR
Length:103
Mass (Da):11,740
Last modified:June 1, 2002 - v1
Checksum:i2BCA7C129AF1E02F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL80305.1.
RefSeqiWP_011011294.1. NC_003413.1.

Genome annotation databases

EnsemblBacteriaiAAL80305; AAL80305; PF0181.
GeneIDi1468013.
KEGGipfu:PF0181.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL80305.1.
RefSeqiWP_011011294.1. NC_003413.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2QAIX-ray2.40A/B1-103[»]
ProteinModelPortaliQ8U4A7.
SMRiQ8U4A7. Positions 1-97.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi186497.PF0181.

Proteomic databases

PRIDEiQ8U4A7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL80305; AAL80305; PF0181.
GeneIDi1468013.
KEGGipfu:PF0181.

Phylogenomic databases

eggNOGiarCOG04102. Archaea.
COG1436. LUCA.
HOGENOMiHOG000056544.
KOiK02122.
OMAiQIPDKFG.

Miscellaneous databases

EvolutionaryTraceiQ8U4A7.

Family and domain databases

Gene3Di3.40.50.10580. 1 hit.
HAMAPiMF_00312. ATP_synth_F_arch.
InterProiIPR008218. ATPase_V1-cplx_f_g_su.
IPR022944. ATPase_V1-cplx_fsu_bac/arc.
IPR005772. ATPase_V1-cplx_fsu_euk.
[Graphical view]
PANTHERiPTHR13861. PTHR13861. 1 hit.
PfamiPF01990. ATP-synt_F. 1 hit.
[Graphical view]
SUPFAMiSSF159468. SSF159468. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences."
    Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T.
    Genetics 152:1299-1305(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Entry informationi

Entry nameiVATF_PYRFU
AccessioniPrimary (citable) accession number: Q8U4A7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: June 1, 2002
Last modified: May 11, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.