Q8U3Y3 (Q8U3Y3_PYRFU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Acylaminoacyl-peptidase-like protein EMBL AAL80442.1

Gene names

Ordered Locus Names:

PF0318

Organism

Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

Taxonomic identifier

186497 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	620 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 2GOP Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Molecular function	serine-type peptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8U3Y3 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 4D470A066A2B9CB0	FASTA	620	72,980
	10 20 30 40 50 60 MSSIEWNEKT FAKFAYLSDP RTKGELVAYV LTKANLKDNK YENTIVIENL KNNARRFIEN 70 80 90 100 110 120 ATMPRISPDG KKIAFMRANE EKKVSEIWVA DLETLSSKKI LEAKNIRSLE WNEDSRKLLI 130 140 150 160 170 180 VGFKRREDED FIFEDDVPAW FDDLGFFDGE KTTFWIFDTE SEEVIEEFEK PRFSSGIWHR 190 200 210 220 230 240 DKIVVNVPHR EIIPQYFKFW DIYIWEDGKE EKMFEKVSFY AVDSDGERIL LYGKPEKKYM 250 260 270 280 290 300 SEHNKLYIYD GKEVMGILDE VDRGVGQAKI KDGKVYFTLF EEGSVNLYIW DGEIKPIAKG 310 320 330 340 350 360 RHWIMGFDVD EIVVYLKETA TRLRELFTWD GEEKQLTDYN DPIFAKLKTF EPVHFRYKSL 370 380 390 400 410 420 DLEIDGWYMK PELKEGEKAP VIVFVHGGPK GMYGYYFKYE MQLMAAKGYY IVYVNPRGSN 430 440 450 460 470 480 GYSEDFALRV LTRTGLEDFQ DILNGIEEFL KLEPQADRER IGITGISYGG YMTNWALTQS 490 500 510 520 530 540 DLFKAGISEN GISYWLTSYA FSDIGLWFDK EVIGENPLEN ENFRRLSPLF YAKNVKAPIL 550 560 570 580 590 600 LIHSLEDYRC PLDQSLMFYH VLKDLGKEAY IAIFKRGAHG HSIRGQPRHR MKRYKLFVEF 610 620 FERKLKKYEE GFPIEKILKE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The beta-propeller domain of the trilobed protease from Pyrococcus furiosus reveals an open Velcro topology." Bosch J., Tamura T., Tamura N., Baumeister W., Essen L.O. Acta Crystallogr. D Biol. Crystallogr. 63:179-187(2007) [PubMed: 17242511] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 1-347.
[2]	"Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences." Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T. Genetics 152:1299-1305(1999) [PubMed: 10430560] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE009950 Genomic DNA. Translation: AAL80442.1.

RefSeq

NP_578047.1. NC_003413.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2GOP	X-ray	2.00	A/B	1-347	[»]

ProteinModelPortal

Q8U3Y3.

SMR

Q8U3Y3. Positions 10-347.

ModBase

Search...

Protein family/group databases

MEROPS

S09.071.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBPYRT00000005816; EBPYRP00000005677; EBPYRG00000005815.

GeneID

1468153.

GenomeReviews

Gene locus PF0318 in contig AE009950_GR.

KEGG

pfu:PF0318.

NMPDR

fig|186497.1.peg.324.

Phylogenomic databases

GeneTree

EBGT00050000022653.

HOGENOM

HBG645296.

OMA

YLYDGEL.

PhylomeDB

Q8U3Y3.

ProtClustDB

CLSK865315.

Family and domain databases

InterPro

IPR011042. 6-blade_b-propeller_TolB-like.
IPR011659. PD40.
IPR001375. Peptidase_S9.
[Graphical view]

Gene3D

G3DSA:2.120.10.30. 6-blade_b-propeller_TolB-like. 2 hits.

Pfam

PF07676. PD40. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q8U3Y3_PYRFU

Accession

Primary (citable) accession number: Q8U3Y3

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)